HK1214756A1 - 用於通過調整 來調節鐵穩態的方法和組合物 - Google Patents
用於通過調整 來調節鐵穩態的方法和組合物Info
- Publication number
- HK1214756A1 HK1214756A1 HK16102699.2A HK16102699A HK1214756A1 HK 1214756 A1 HK1214756 A1 HK 1214756A1 HK 16102699 A HK16102699 A HK 16102699A HK 1214756 A1 HK1214756 A1 HK 1214756A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- bmp
- modulation
- compositions
- methods
- iron homeostasis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11429008P | 2008-11-13 | 2008-11-13 | |
US14115508P | 2008-12-29 | 2008-12-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1214756A1 true HK1214756A1 (zh) | 2016-08-05 |
Family
ID=42170727
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16102699.2A HK1214756A1 (zh) | 2008-11-13 | 2016-03-09 | 用於通過調整 來調節鐵穩態的方法和組合物 |
Country Status (9)
Country | Link |
---|---|
US (2) | US8318167B2 (zh) |
EP (2) | EP3693014A1 (zh) |
JP (2) | JP6018753B2 (zh) |
CN (2) | CN104922669A (zh) |
AU (1) | AU2009313902B9 (zh) |
CA (2) | CA3019967A1 (zh) |
ES (1) | ES2766257T3 (zh) |
HK (1) | HK1214756A1 (zh) |
WO (1) | WO2010056981A2 (zh) |
Families Citing this family (22)
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US20110070242A1 (en) * | 2009-09-01 | 2011-03-24 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for Diagnosing and Treating Iron Dysregulation |
BR112012017106A2 (pt) | 2010-01-11 | 2018-05-29 | Inotek Pharmaceuticals Corp | combinação, kit e método de redução de pressão intraocular. |
SG184221A1 (en) | 2010-03-26 | 2012-10-30 | Inotek Pharmaceuticals Corp | Method of reducing intraocular pressure in humans using n6 -cyclopentyladenosine (cpa), cpa derivatives or prodrugs thereof |
CN103649126B (zh) * | 2011-01-19 | 2016-11-09 | 菲卢马克斯制药公司 | 用于调节铁稳态的组合物及其使用方法 |
EP3450568A3 (en) | 2011-03-04 | 2019-04-24 | Intrexon Corporation | Vectors conditionally expressing protein |
MX356933B (es) * | 2011-12-14 | 2018-06-20 | Abbvie Deutschland | Composicion y metodo para el diagnostico y tratamiento de trastornos relacionados con hierro. |
CA2855840C (en) | 2011-12-14 | 2023-08-29 | AbbVie Deutschland GmbH & Co. KG | Composition and method for the diagnosis and treatment of iron-related disorders |
MX2014009086A (es) | 2012-01-26 | 2015-06-05 | Inotek Pharmaceuticals Corp | Polimorfos anhidros de nitrato de [ (2r,3s,4r,5r) -5- (6- (ciclopentilamino) -9h-purin-9-il) -3,4-dihidroxitetra-hidrofuran- 2-il) ] metilo y procesos para su preparación. |
AR093620A1 (es) | 2012-12-17 | 2015-06-10 | Lilly Co Eli | Anticuerpos bmp-6 |
CN103255143A (zh) * | 2013-01-24 | 2013-08-21 | 新疆维吾尔自治区畜牧科学院中国-澳大利亚绵羊育种研究中心 | 一个抑制BMPR-lB基因表达合成的shRNA分子 |
NZ630759A (en) | 2013-03-15 | 2017-07-28 | Inotek Pharmaceuticals Corp | Ophthalmic formulations comprising an a1 agonist |
JP6463331B2 (ja) | 2013-03-15 | 2019-01-30 | イントリンシック ライフサイエンシズ リミテッド ライアビリティ カンパニー | 抗ヘプシジン抗体およびその使用 |
US9139648B1 (en) | 2014-07-15 | 2015-09-22 | Kymab Limited | Precision medicine by targeting human NAV1.9 variants for treatment of pain |
EP3197915A4 (en) | 2014-09-22 | 2018-12-19 | Intrinsic Lifesciences LLC | Humanized anti-hepcidin antibodies and uses thereof |
WO2016071701A1 (en) * | 2014-11-07 | 2016-05-12 | Kymab Limited | Treatment of disease using ligand binding to targets of interest |
UY36449A (es) * | 2014-12-19 | 2016-07-29 | Novartis Ag | Composiciones y métodos para anticuerpos dirigidos a bmp6 |
EA039579B1 (ru) * | 2014-12-19 | 2022-02-14 | Новартис Аг | Способы и композиции антител, направленных против bmp6 |
GB2550114A (en) | 2016-05-03 | 2017-11-15 | Kymab Ltd | Methods, regimens, combinations & antagonists |
WO2017216724A1 (en) | 2016-06-15 | 2017-12-21 | Novartis Ag | Methods for treating disease using inhibitors of bone morphogenetic protein 6 (bmp6) |
EP3415527A1 (de) | 2017-06-14 | 2018-12-19 | Technische Universität Dresden | Verwendung der extrazellulären domäne des transferrinrezeptor 2 zur diagnostik und behandlung von primär und sekundär sklerosierenden erkrankungen |
RU2020117439A (ru) * | 2017-11-02 | 2021-12-02 | Байер Акциенгезельшафт | БИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА, СВЯЗЫВАЮЩИЕ ALK-1 и BMPR-2 |
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-
2009
- 2009-11-13 EP EP19204622.5A patent/EP3693014A1/en not_active Withdrawn
- 2009-11-13 CA CA3019967A patent/CA3019967A1/en not_active Abandoned
- 2009-11-13 AU AU2009313902A patent/AU2009313902B9/en not_active Ceased
- 2009-11-13 WO PCT/US2009/064369 patent/WO2010056981A2/en active Application Filing
- 2009-11-13 US US12/618,319 patent/US8318167B2/en active Active
- 2009-11-13 EP EP09826827.9A patent/EP2349332B1/en not_active Revoked
- 2009-11-13 CA CA2742871A patent/CA2742871C/en not_active Expired - Fee Related
- 2009-11-13 JP JP2011536510A patent/JP6018753B2/ja active Active
- 2009-11-13 CN CN201510184557.XA patent/CN104922669A/zh active Pending
- 2009-11-13 CN CN200980145449.4A patent/CN102215869B/zh active Active
- 2009-11-13 ES ES09826827T patent/ES2766257T3/es active Active
-
2015
- 2015-01-30 JP JP2015017776A patent/JP6104295B2/ja active Active
-
2016
- 2016-03-09 HK HK16102699.2A patent/HK1214756A1/zh unknown
-
2017
- 2017-05-18 US US15/599,420 patent/US20170362311A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2766257T3 (es) | 2020-06-12 |
CA2742871C (en) | 2018-10-23 |
JP2012508764A (ja) | 2012-04-12 |
EP2349332A4 (en) | 2013-09-04 |
EP2349332B1 (en) | 2019-10-23 |
CN102215869A (zh) | 2011-10-12 |
CN104922669A (zh) | 2015-09-23 |
CN102215869B (zh) | 2015-05-13 |
US20170362311A1 (en) | 2017-12-21 |
US8318167B2 (en) | 2012-11-27 |
EP3693014A1 (en) | 2020-08-12 |
CA3019967A1 (en) | 2010-05-20 |
AU2009313902B9 (en) | 2014-03-27 |
JP6104295B2 (ja) | 2017-03-29 |
WO2010056981A2 (en) | 2010-05-20 |
AU2009313902A1 (en) | 2011-06-30 |
EP2349332A2 (en) | 2011-08-03 |
CA2742871A1 (en) | 2010-05-20 |
US20100136015A1 (en) | 2010-06-03 |
WO2010056981A3 (en) | 2010-09-16 |
JP6018753B2 (ja) | 2016-11-02 |
JP2015129141A (ja) | 2015-07-16 |
AU2009313902B2 (en) | 2014-03-06 |
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