HK1213485A1 - 促生長素抑制素-多巴胺嵌合類似物 - Google Patents

促生長素抑制素-多巴胺嵌合類似物

Info

Publication number
HK1213485A1
HK1213485A1 HK16101501.2A HK16101501A HK1213485A1 HK 1213485 A1 HK1213485 A1 HK 1213485A1 HK 16101501 A HK16101501 A HK 16101501A HK 1213485 A1 HK1213485 A1 HK 1213485A1
Authority
HK
Hong Kong
Prior art keywords
somatostatin
dopamine chimeric
chimeric analogs
analogs
dopamine
Prior art date
Application number
HK16101501.2A
Other languages
English (en)
Inventor
Zheng Xin Dong
Yeelana Shen
Sun Hyuk Kim
Original Assignee
Ipsen Pharma Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Pharma Sas filed Critical Ipsen Pharma Sas
Publication of HK1213485A1 publication Critical patent/HK1213485A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
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    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/52—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

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  • Veterinary Medicine (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
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  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
HK16101501.2A 2012-11-01 2016-02-11 促生長素抑制素-多巴胺嵌合類似物 HK1213485A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261721372P 2012-11-01 2012-11-01
PCT/US2013/067661 WO2014070971A2 (en) 2012-11-01 2013-10-31 Somatostatin-dopamine chimeric analogs

Publications (1)

Publication Number Publication Date
HK1213485A1 true HK1213485A1 (zh) 2016-07-08

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ID=50547875

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16101501.2A HK1213485A1 (zh) 2012-11-01 2016-02-11 促生長素抑制素-多巴胺嵌合類似物

Country Status (18)

Country Link
US (3) US8952128B2 (zh)
EP (1) EP2914280B1 (zh)
JP (2) JP5908184B2 (zh)
KR (1) KR101770231B1 (zh)
CN (1) CN104768570B (zh)
AR (1) AR093327A1 (zh)
AU (1) AU2013337851A1 (zh)
BR (1) BR112015009602A2 (zh)
CA (1) CA2888765A1 (zh)
EA (1) EA038157B1 (zh)
ES (1) ES2663956T3 (zh)
HK (1) HK1213485A1 (zh)
IL (1) IL238080A0 (zh)
MX (1) MX2015005531A (zh)
SA (1) SA515360377B1 (zh)
SG (1) SG11201502486RA (zh)
TW (1) TWI523863B (zh)
WO (1) WO2014070971A2 (zh)

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Publication number Priority date Publication date Assignee Title
TWI523863B (zh) * 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物
US9777039B2 (en) 2012-11-01 2017-10-03 Ipsen Pharma S.A.S. Somatostatin analogs and dimers thereof
CN105820215A (zh) * 2016-05-09 2016-08-03 中国人民解放军第二军医大学 一种高效合成Stylissatin A天然环七肽的制备方法
CN112739222A (zh) * 2018-09-14 2021-04-30 田中惠 抗衰老剂以及抗衰老方法

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US20150290330A1 (en) 2015-10-15
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US20150148522A1 (en) 2015-05-28
WO2014070971A2 (en) 2014-05-08
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US9731027B2 (en) 2017-08-15
EP2914280A2 (en) 2015-09-09
KR20150076195A (ko) 2015-07-06
EP2914280A4 (en) 2016-04-27
US9603942B2 (en) 2017-03-28
IL238080A0 (en) 2015-05-31
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TW201422636A (zh) 2014-06-16
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EA201590841A1 (ru) 2015-12-30
TWI523863B (zh) 2016-03-01
WO2014070971A3 (en) 2014-07-03
AR093327A1 (es) 2015-06-03
US8952128B2 (en) 2015-02-10
JP5908184B2 (ja) 2016-04-26
CA2888765A1 (en) 2014-05-08
SA515360377B1 (ar) 2016-10-10
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US20140121354A1 (en) 2014-05-01
CN104768570B (zh) 2017-12-15

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