HK1210913A1 - Particles, methods and uses thereof - Google Patents

Particles, methods and uses thereof

Info

Publication number
HK1210913A1
HK1210913A1 HK15111637.9A HK15111637A HK1210913A1 HK 1210913 A1 HK1210913 A1 HK 1210913A1 HK 15111637 A HK15111637 A HK 15111637A HK 1210913 A1 HK1210913 A1 HK 1210913A1
Authority
HK
Hong Kong
Prior art keywords
particles
methods
Prior art date
Application number
HK15111637.9A
Other languages
English (en)
Chinese (zh)
Inventor
莫里茨.基爾舍
斯特凡.哈姆森
馬修.瓦爾
Original Assignee
Sloan Kettering Inst Cancer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan Kettering Inst Cancer filed Critical Sloan Kettering Inst Cancer
Publication of HK1210913A1 publication Critical patent/HK1210913A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0063Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1878Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles the nanoparticle having a magnetically inert core and a (super)(para)magnetic coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1878Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles the nanoparticle having a magnetically inert core and a (super)(para)magnetic coating
    • A61K49/1881Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles the nanoparticle having a magnetically inert core and a (super)(para)magnetic coating wherein the coating consists of chelates, i.e. chelating group complexing a (super)(para)magnetic ion, bound to the surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1244Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles
    • A61K51/1251Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins microparticles or nanoparticles, e.g. polymeric nanoparticles micro- or nanospheres, micro- or nanobeads, micro- or nanocapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Nuclear Medicine (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
HK15111637.9A 2012-08-31 2015-11-26 Particles, methods and uses thereof HK1210913A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261696122P 2012-08-31 2012-08-31
PCT/US2013/057636 WO2014036470A1 (en) 2012-08-31 2013-08-30 Particles, methods and uses thereof

Publications (1)

Publication Number Publication Date
HK1210913A1 true HK1210913A1 (en) 2016-05-13

Family

ID=50184445

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15111637.9A HK1210913A1 (en) 2012-08-31 2015-11-26 Particles, methods and uses thereof

Country Status (8)

Country Link
US (1) US10322194B2 (xx)
EP (1) EP2892352B1 (xx)
JP (2) JP6654897B2 (xx)
CN (1) CN104684398A (xx)
AU (1) AU2013308472B2 (xx)
CA (1) CA2882388C (xx)
HK (1) HK1210913A1 (xx)
WO (1) WO2014036470A1 (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2882388C (en) 2012-08-31 2020-10-20 Sloan-Kettering Institute For Cancer Research Particles, methods and uses thereof
US10105456B2 (en) 2012-12-19 2018-10-23 Sloan-Kettering Institute For Cancer Research Multimodal particles, methods and uses thereof
CA2900686A1 (en) 2013-02-20 2014-08-28 Sloan-Kettering Institute For Cancer Research Wide field raman imaging apparatus and associated methods
WO2015051465A1 (en) * 2013-10-11 2015-04-16 Héma-Québec Nanoparticular antibodies and uses thereof as contrast agents
US10912947B2 (en) 2014-03-04 2021-02-09 Memorial Sloan Kettering Cancer Center Systems and methods for treatment of disease via application of mechanical force by controlled rotation of nanoparticles inside cells
US10688202B2 (en) 2014-07-28 2020-06-23 Memorial Sloan-Kettering Cancer Center Metal(loid) chalcogen nanoparticles as universal binders for medical isotopes
US11504437B2 (en) * 2014-08-11 2022-11-22 William Marsh Rice University Multifunctional fluorescent and MRI-active nanostructure
US10919089B2 (en) 2015-07-01 2021-02-16 Memorial Sloan Kettering Cancer Center Anisotropic particles, methods and uses thereof
JP7042739B2 (ja) * 2015-08-20 2022-03-28 イプセン バイオファーム リミティド 癌処置のためのリポソーム型イリノテカン及びparp阻害薬を使用する併用療法
CN106556960B (zh) * 2015-09-29 2019-03-12 宁波舜宇光电信息有限公司 离焦转换系数验证方法
WO2017123742A1 (en) * 2016-01-12 2017-07-20 Rutgers, The State University Of New Jersey Multiplexed assays
WO2019014854A1 (zh) * 2017-07-18 2019-01-24 纳狮新材料股份有限公司 功能复合粒子及其制备方法
WO2019018707A1 (en) * 2017-07-21 2019-01-24 Memorial Sloan Kettering Cancer Center NANOPARTICLES, METHODS AND USES THEREOF
US20220362577A1 (en) * 2019-06-20 2022-11-17 University Of Vermont And State Agricultural College Methods for guiding direct delivery of drugs and/or energy to lesions using computational modeling
CN110238387A (zh) * 2019-06-25 2019-09-17 纳狮新材料(浙江)有限公司 功能复合粒子及其制备方法
CN110280778B (zh) * 2019-07-05 2021-12-10 中国计量大学 一种Ag@ZrO2核-壳纳米材料及其制备方法和应用
US20230133393A1 (en) * 2020-02-27 2023-05-04 University Of Houston System Diboride micropatterned surfaces for cell culture
CN115893867B (zh) * 2022-11-22 2023-11-21 上海韦地科技集团有限公司 一种耐辐照光学玻璃及其制备方法

Family Cites Families (168)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4127329A (en) 1976-12-21 1978-11-28 Northeast Utilities Service Company Raman scattering system and method for aerosol monitoring
JPS60137342A (ja) 1983-12-27 1985-07-20 オリンパス光学工業株式会社 電子スコ−プ
US4669467A (en) 1985-03-22 1987-06-02 Massachusetts Institute Of Technology Mode mixer for a laser catheter
US4938205A (en) 1988-05-27 1990-07-03 The University Of Connecticut Endoscope with traced raster and elemental photodetectors
JPH04501265A (ja) 1988-10-14 1992-03-05 マリンクロッド・インコーポレイテッド ラジオ標識粒状組成物
US5275594A (en) 1990-11-09 1994-01-04 C. R. Bard, Inc. Angioplasty system having means for identification of atherosclerotic plaque
US6006126A (en) 1991-01-28 1999-12-21 Cosman; Eric R. System and method for stereotactic registration of image scan data
US5300097A (en) 1991-02-13 1994-04-05 Lerner Ethan A Fiber optic psoriasis treatment device
US5293872A (en) 1991-04-03 1994-03-15 Alfano Robert R Method for distinguishing between calcified atherosclerotic tissue and fibrous atherosclerotic tissue or normal cardiovascular tissue using Raman spectroscopy
WO1993003672A1 (en) 1991-08-20 1993-03-04 Redd Douglas C B Optical histochemical analysis, in vivo detection and real-time guidance for ablation of abnormal tissues using a raman spectroscopic detection system
US5306403A (en) 1992-08-24 1994-04-26 Martin Marietta Energy Systems, Inc. Raman-based system for DNA sequencing-mapping and other separations
DE69416829D1 (de) 1993-04-07 1999-04-08 Ahern John M Endoskop mit einem an seiner spitze angeordneten ccd-farbsensor
US5491510A (en) 1993-12-03 1996-02-13 Texas Instruments Incorporated System and method for simultaneously viewing a scene and an obscured object
US5609907A (en) 1995-02-09 1997-03-11 The Penn State Research Foundation Self-assembled metal colloid monolayers
US6025202A (en) 1995-02-09 2000-02-15 The Penn State Research Foundation Self-assembled metal colloid monolayers and detection methods therewith
US5949388A (en) 1995-03-03 1999-09-07 Olympus Optical Co., Ltd. Head-mounted video display
JPH095666A (ja) 1995-06-15 1997-01-10 Olympus Optical Co Ltd 頭部装着型映像表示装置
GB9517955D0 (en) 1995-07-25 1995-11-08 Univ Strathclyde Nucleotide sequence detection and analysis
US5713364A (en) 1995-08-01 1998-02-03 Medispectra, Inc. Spectral volume microprobe analysis of materials
US5813987A (en) 1995-08-01 1998-09-29 Medispectra, Inc. Spectral volume microprobe for analysis of materials
US6174677B1 (en) 1995-10-13 2001-01-16 Ut-Battelle, Llc Advanced surface-enhanced Raman gene probe systems and methods thereof
US5814516A (en) 1995-10-13 1998-09-29 Lockheed Martin Energy Systems, Inc. Surface enhanced Raman gene probe and methods thereof
WO1998010289A1 (en) 1996-09-04 1998-03-12 The Penn State Research Foundation Self-assembled metal colloid monolayers
US6002471A (en) 1996-11-04 1999-12-14 California Institute Of Technology High resolution scanning raman microscope
DE19647855B4 (de) 1996-11-19 2007-09-27 Henke-Sass Wolf Gmbh Voll autoklavierbares elektronisches Endoskop
US6008889A (en) 1997-04-16 1999-12-28 Zeng; Haishan Spectrometer system for diagnosis of skin disease
US6251127B1 (en) 1997-08-25 2001-06-26 Advanced Photodynamic Technologies, Inc. Dye treatment solution and photodynamic therapy and method of using same
JPH1184307A (ja) 1997-09-01 1999-03-26 M R Syst Kenkyusho:Kk 頭部装着型の光学装置
US6174291B1 (en) 1998-03-09 2001-01-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
US20020163482A1 (en) 1998-04-20 2002-11-07 Alan Sullivan Multi-planar volumetric display system including optical elements made from liquid crystal having polymer stabilized cholesteric textures
US6219137B1 (en) 1998-12-03 2001-04-17 Lockheed Martin Energy Research Corporation Nanoprobe for surface-enhanced Raman spectroscopy in medical diagnostic and drug screening
US6228076B1 (en) 1999-01-09 2001-05-08 Intraluminal Therapeutics, Inc. System and method for controlling tissue ablation
JP4849755B2 (ja) 1999-07-02 2012-01-11 ハイパースペクトラル・イメージング・インコーポレイテツド イメージング装置および試料分析方法
US6254852B1 (en) 1999-07-16 2001-07-03 Dupont Pharmaceuticals Company Porous inorganic targeted ultrasound contrast agents
US6788860B1 (en) 1999-07-19 2004-09-07 Chemimage Corporation Chemical imaging fiberscope
US6579726B1 (en) 1999-07-30 2003-06-17 Surromed, Inc. Instruments, methods and reagents for surface plasmon resonance
US7192778B2 (en) 1999-10-06 2007-03-20 Natan Michael J Surface enhanced spectroscopy-active composite nanoparticles
AU8000400A (en) 1999-10-06 2001-05-10 Surromed, Inc. Surface enhanced spectroscopy-active composite nanoparticles
US8497131B2 (en) 1999-10-06 2013-07-30 Becton, Dickinson And Company Surface enhanced spectroscopy-active composite nanoparticles comprising Raman-active reporter molecules
AU1945901A (en) 1999-12-03 2001-06-12 Surromed, Inc. Hydroxylamine seeding of colloidal metal nanoparticles
WO2002079764A1 (en) 2001-01-26 2002-10-10 Nanoplex Technologies, Inc. Surface-enhanced spectroscopy-active sandwich nanoparticles
AU2001259435A1 (en) 2000-05-03 2001-11-12 Stephen T Flock Optical imaging of subsurface anatomical structures and biomolecules
US6748259B1 (en) 2000-06-15 2004-06-08 Spectros Corporation Optical imaging of induced signals in vivo under ambient light conditions
US20030158545A1 (en) 2000-09-28 2003-08-21 Arthrocare Corporation Methods and apparatus for treating back pain
US20020082498A1 (en) 2000-10-05 2002-06-27 Siemens Corporate Research, Inc. Intra-operative image-guided neurosurgery with augmented reality visualization
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
US6623513B2 (en) 2001-01-19 2003-09-23 Advanced Photodynamic Technologies, Inc. Apparatus and method of photodynamic eradication of organisms utilizing pyrrolnitrin
JP2005502618A (ja) 2001-06-04 2005-01-27 ザ・ジェネラル・ホスピタル・コーポレイション 光力学的化合物を用いて脆弱なプラークを検出および治療する方法
WO2002100285A1 (en) 2001-06-13 2002-12-19 Volume Interactions Pte Ltd A guide system and a probe therefor
US7076092B2 (en) 2001-06-14 2006-07-11 The United States Of America As Represented By The United States Department Of Energy High-throughput, dual probe biological assays based on single molecule detection
US7214428B2 (en) * 2001-09-17 2007-05-08 Invitrogen Corporation Highly luminescent functionalized semiconductor nanocrystals for biological and physical applications
US8808268B2 (en) 2002-02-14 2014-08-19 Gholam A. Peyman Method and composition for hyperthermally treating cells
US6959024B2 (en) 2002-02-28 2005-10-25 Picarro, Inc. Laser Tuning by spectrally dependent spatial filtering
US20040073120A1 (en) 2002-04-05 2004-04-15 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
US6711426B2 (en) 2002-04-09 2004-03-23 Spectros Corporation Spectroscopy illuminator with improved delivery efficiency for high optical density and reduced thermal load
US8697029B2 (en) 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
DE10249674B4 (de) 2002-10-24 2014-12-24 Carl Zeiss Meditec Ag Operationsinstrument zum Schneiden, Abtragen oder Absaugen von Material in einem Operationsgebiet
WO2004069040A2 (en) 2003-02-04 2004-08-19 Z-Kat, Inc. Method and apparatus for computer assistance with intramedullary nail procedure
US20040254419A1 (en) 2003-04-08 2004-12-16 Xingwu Wang Therapeutic assembly
US20040225222A1 (en) 2003-05-08 2004-11-11 Haishan Zeng Real-time contemporaneous multimodal imaging and spectroscopy uses thereof
US20050014851A1 (en) 2003-07-18 2005-01-20 Eastman Kodak Company Colloidal core-shell assemblies and methods of preparation
US6977143B1 (en) 2003-09-08 2005-12-20 Quest Diagnostics Investments Incorporated Determination of testosterone by mass spectrometry
US20050074779A1 (en) 2003-10-02 2005-04-07 Tuan Vo-Dinh SERS molecular probe for diagnostics and therapy
NZ546918A (en) 2003-10-03 2009-01-31 Amc Amsterdam System and method for imaging the reflectance of a substrate
AU2004279443A1 (en) 2003-10-08 2005-04-21 Nomir Medical Technologies, Inc. Use of secondary optical emission as a novel biofilm targeting technology
US20080118912A1 (en) 2004-03-10 2008-05-22 Robert Martin Dickson Raman-Enhancing, and Non-Linear Optically Active Nano-Sized Optical Labels and Uses Thereof
JP2005306827A (ja) 2004-04-17 2005-11-04 Isao Shimizu 生体高分子結晶迅速精製・計測の方法および装置
US8128908B2 (en) 2004-04-30 2012-03-06 University Of Florida Research Foundation, Inc. Nanoparticles and their use for multifunctional bioimaging
US7697576B2 (en) 2004-05-05 2010-04-13 Chem Image Corporation Cytological analysis by raman spectroscopic imaging
US20050251116A1 (en) 2004-05-05 2005-11-10 Minnow Medical, Llc Imaging and eccentric atherosclerotic material laser remodeling and/or ablation catheter
US20070238953A1 (en) 2004-06-17 2007-10-11 Koninklijke Philips Electronics, N.V. Combined ultrasonic imaging and spectroscopic molecular analysis
US20060098194A1 (en) 2004-11-08 2006-05-11 David Tuschel Method and apparatus for determining change in an attribute of a sample during nucleation, aggregation, or chemical interaction
US20080089839A1 (en) 2004-09-16 2008-04-17 Guo-Quan Lu Preparation of Stable High Concentration Coloidal Metal Particulate System
US7738096B2 (en) 2004-10-21 2010-06-15 University Of Georgia Research Foundation, Inc. Surface enhanced Raman spectroscopy (SERS) systems, substrates, fabrication thereof, and methods of use thereof
US7656525B2 (en) 2004-10-21 2010-02-02 University Of Georgia Research Foundation, Inc. Fiber optic SERS sensor systems and SERS probes
NZ561491A (en) * 2005-02-14 2009-10-30 Australian Nuclear Science Tec Layered nanoparticles
WO2006135344A1 (en) 2005-06-13 2006-12-21 National University Of Singapore A photosensitising composition and uses thereof
US8540965B2 (en) 2005-07-29 2013-09-24 Sloan-Kettering Institute For Cancer Research Single wall nanotube constructs and uses therefor
JP4749805B2 (ja) 2005-09-05 2011-08-17 オリンパスメディカルシステムズ株式会社 ラマン散乱光観測装置
WO2007040589A1 (en) 2005-09-16 2007-04-12 The Regents Of The University Of Michigan Method and system for measuring sub-surface composition of a sample
ES2301296B1 (es) 2005-09-16 2009-05-29 Consejo Superior Investig. Cientificas Manoparticula biosensora, procedimiento de elaboracion y sus aplicaciones.
WO2007036950A1 (en) 2005-09-29 2007-04-05 The Director General Defence Research & Development Organisation Single-source precursor for semiconductor nanocrystals
US20100322471A1 (en) 2005-10-07 2010-12-23 Chemimage Corporation Motion invariant generalized hyperspectral targeting and identification methodology and apparatus therefor
GB2431233A (en) 2005-10-14 2007-04-18 E2V Tech Molecular detector arrangement
EP1945794A2 (en) 2005-11-09 2008-07-23 Chemimage Corporation System and method for cytological analysis by raman spectroscopic imaging
WO2007084210A2 (en) 2005-11-10 2007-07-26 Chemimage Corporation System and method for a raman and/or fluorescence colposcope
US8320650B2 (en) 2005-11-30 2012-11-27 Lawrence Livermore National Security, Llc In vivo spectral micro-imaging of tissue
US8409863B2 (en) 2005-12-14 2013-04-02 Becton, Dickinson And Company Nanoparticulate chemical sensors using SERS
EP2659851A3 (en) 2006-02-01 2014-01-15 The General Hospital Corporation Apparatus for applying a plurality of electro-magnetic radiations to a sample
JP5266066B2 (ja) 2006-02-08 2013-08-21 ベクトン・ディキンソン・アンド・カンパニー Sersナノタグアッセイ
US7829140B1 (en) * 2006-03-29 2010-11-09 The Research Foundation Of The State University Of New York Method of forming iron oxide core metal shell nanoparticles
JP4675812B2 (ja) 2006-03-30 2011-04-27 株式会社東芝 磁気記録媒体、磁気記録装置および磁気記録媒体の製造方法
US20090263485A1 (en) 2008-03-01 2009-10-22 Chun Li Targeted hollow gold nanostructures and methods of use
CN101432044A (zh) 2006-04-28 2009-05-13 恩迪尼国际有限公司 光消毒装置和方法
US8057464B2 (en) 2006-05-03 2011-11-15 Light Sciences Oncology, Inc. Light transmission system for photoreactive therapy
US8774902B2 (en) 2006-06-01 2014-07-08 Passive Imaging Medical Systems Engineering Ltd. (Pims) Method of infrared thermography for earlier diagnosis of gastric colorectal and cervical cancer
US20080119832A1 (en) 2006-11-16 2008-05-22 Molten Labs, Inc. Multi-Modal Scanning Confocal Adaptive-Optic Macroscope System and Associated Methods
EP2092297A4 (en) 2006-11-21 2018-01-17 California Institute of Technology Second harmonic imaging nanoprobes and techniques for use thereof
EP2134642B1 (en) * 2007-04-02 2016-02-24 Emory University SERS nanoparticle tags and method for spectroscopic detection of tumors
US8376013B2 (en) 2008-03-11 2013-02-19 Duke University Plasmonic assisted systems and methods for interior energy-activation from an exterior source
WO2009020680A2 (en) 2007-05-04 2009-02-12 Stanford University Molecular imaging of living subjects using raman spectroscopy and labeled raman nanoparticles
WO2008144028A1 (en) 2007-05-14 2008-11-27 The Johns Hopkins University Methods for in vivo imaging of cells
US20080305045A1 (en) * 2007-06-07 2008-12-11 Prabhakaran Kuniyil Methods of synthesis of non-toxic multifunctional nanoparticles and applications
KR20090001013A (ko) 2007-06-29 2009-01-08 주식회사 웰스킨 인돌-3-알킬카복실산을 함유하는 여드름 치료제 및 피지분비 억제제, 및 이를 포함하는 광역학적 치료용 키트
JP5222497B2 (ja) 2007-07-04 2013-06-26 日本発條株式会社 オットマン装置
WO2009079056A2 (en) 2007-09-22 2009-06-25 Boise State University Fluorescent particles comprising nanoscale zno layer and exhibiting cell-specific toxicity
JP2009115546A (ja) 2007-11-05 2009-05-28 Fujifilm Corp 分析装置
US9302116B2 (en) * 2007-11-06 2016-04-05 Duke University Non-invasive energy upconversion methods and systems for in-situ photobiomodulation
US20090171330A1 (en) 2007-12-28 2009-07-02 Spectranetics Tunable nanoparticle tags to enhance tissue recognition
ES2689302T3 (es) 2008-02-13 2018-11-13 Andreas Rose Dispositivo de suministro de luz que proporciona un patrón radial de emisión de luz
US20100279272A1 (en) 2008-02-13 2010-11-04 Michael Craig Burrell Multiplexed analysis methods using sers-active nanoparticles
US7760352B2 (en) 2008-03-18 2010-07-20 Itt Manufacturing Enterprises, Inc. Dual pulse single event Raman spectroscopy
CN105288619A (zh) 2008-04-04 2016-02-03 免疫之光有限责任公司 用于原位光生物调节的非侵入性系统和方法
US20090281536A1 (en) 2008-05-09 2009-11-12 Hugh Beckman Medical Device For Diagnosing and Treating Anomalous Tissue and Method for Doing the Same
EP2307886A2 (en) 2008-06-26 2011-04-13 Dana-Farber Cancer Institute Inc. Signatures and determinants associated with metastasis and methods of use thereof
US8770203B2 (en) * 2008-07-14 2014-07-08 Immunolight, Llc. Advanced methods and systems for treating cell proliferation disorders
US8416405B2 (en) 2008-08-08 2013-04-09 Chemimage Corporation Raman chemical imaging of implantable drug delivery devices
US8780176B2 (en) 2008-08-15 2014-07-15 Technion Research & Development Foundation Limited Vessel imaging system and method
KR20100030195A (ko) 2008-09-09 2010-03-18 서울대학교산학협력단 방사성 표지된 형광 실리카 나노파티클 및 이를 이용한 pet 및 형광 복합영상 측정방법
WO2010057212A1 (en) 2008-11-17 2010-05-20 Oxonica Materials, Inc. Melamine assay methods and systems
JP5500875B2 (ja) 2009-01-30 2014-05-21 キヤノン株式会社 新規化合物、該新規化合物を用いたプローブ及び該新規化合物もしくは該プローブを用いた蛍光イメージング用造影剤
WO2010096828A1 (en) 2009-02-23 2010-08-26 The Regents Of The University Of California Multi-modality nanoparticles having optically responsive shape
WO2010111066A2 (en) 2009-03-23 2010-09-30 The General Hospital Corporation Innately multimodal nanoparticles
EP2470100B1 (en) 2009-08-27 2017-09-20 New Jersey Institute of Technology Integrated fiber optic raman spectroscopy and radio frequency ablation
EP3483610A1 (en) 2009-11-09 2019-05-15 University Of Washington Center For Commercialization Functionalized chromophoric polymer dots and bioconjugates thereof
FR2952368B1 (fr) 2009-11-10 2012-01-13 Commissariat Energie Atomique Particule de silice incorporant une molecule d'interet, son procede de preparation et ses utilisations.
US8862206B2 (en) 2009-11-12 2014-10-14 Virginia Tech Intellectual Properties, Inc. Extended interior methods and systems for spectral, optical, and photoacoustic imaging
CN102811943B (zh) 2009-12-11 2015-08-19 韩国化学研究院 以位于粒子间的结合部的拉曼活性分子标记的二聚体核壳纳米结构、其用途及制备方法
AU2010339972B2 (en) 2009-12-15 2015-04-30 Emory University System and method for providing real-time anatomical guidance in a diagnostic or therapeutic procedure
CN102740762A (zh) 2010-01-22 2012-10-17 不列颠哥伦比亚癌症分社 由拉曼光谱法表征肺组织的设备和方法
JP2011158334A (ja) 2010-01-29 2011-08-18 Beckman Coulter Inc 分析方法、分析装置および分析プログラム
US20110261351A1 (en) 2010-02-05 2011-10-27 Chemimage Corporation System and method for detecting explosives using swir and mwir hyperspectral imaging
JP2013521900A (ja) 2010-03-17 2013-06-13 ズオン、ハイシャン 高速マルチスペクトルイメージングの方法および装置と癌検出および局在診断への応用
US20110242533A1 (en) 2010-04-05 2011-10-06 Chemimage Corporation System and Method for Detecting Hazardous Agents Including Explosives
US8568878B2 (en) 2010-04-08 2013-10-29 The Board Of Trustees Of The Leland Stanford Junior University Directly fabricated nanoparticles for raman scattering
US9086533B1 (en) 2010-06-08 2015-07-21 Cirrex Systems, Llc Method and system for coupling light through challenging media
KR101207695B1 (ko) 2010-08-11 2012-12-03 서울대학교산학협력단 형광 및 라만 신호 표적에 대한 형광 및 라만 신호 동시검출방법 및 이를 이용한 표적 동시검출용 의학영상장치
US20130342683A1 (en) 2010-10-06 2013-12-26 Chemimage Corporation System and Method for Detecting Environmental Conditions Using Hyperspectral Imaging
US8873038B2 (en) 2010-10-27 2014-10-28 The Board Of Trustees Of The University Of Illinois Tailored raman spectrocopic probes for ultrasensitive and highly multiplexed assays
US9345389B2 (en) 2010-11-12 2016-05-24 Emory University Additional systems and methods for providing real-time anatomical guidance in a diagnostic or therapeutic procedure
EP2641079A2 (en) 2010-11-15 2013-09-25 Tissuevision, Inc. Systems and methods for imaging and processing tissue
KR101352342B1 (ko) 2010-11-24 2014-02-17 서울대학교산학협력단 코어 물질과 쉘 물질 사이에 나노갭이 형성된 단일 나노입자 및 이의 제조방법
CN102175655B (zh) 2010-12-24 2013-10-30 东南大学 一种双模式光学成像探针及其制备方法
US9833144B2 (en) 2011-01-07 2017-12-05 The Board Of Trustees Of The Leland Stanford Junior University Probes, methods of making probes, and methods of use
US20120251450A1 (en) 2011-04-04 2012-10-04 Alex Punnoose Nanoparticles that preferentially associate with and kill diseased cells for diagnostic and therapeutic applications
US20120302940A1 (en) 2011-05-26 2012-11-29 Jackson State University Popcorn Shape Gold Nanoparticle For Targeted Diagnosis, Photothermal Treatment and In-Situ Monitoring Therapy Response for Cancer and Multiple Drug Resistance Bacteria
JP6073295B2 (ja) 2011-05-27 2017-02-01 コナヴィ メディカル インコーポレーテッド 流体回転ジョイントを備える医療用プローブ
DE102011103950B4 (de) 2011-06-06 2015-02-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zum Erfassen und Entfernen von schädlichem Gewebe
CN102410994B (zh) 2011-07-27 2013-12-11 东南大学 一种磁性双模式光学探针及其制备方法
US20140316255A1 (en) 2011-09-02 2014-10-23 Ellis Garai Raman Imaging Devices and Methods of Molecular Imaging
US9585721B2 (en) 2011-10-28 2017-03-07 Navigate Surgical Technologies, Inc. System and method for real time tracking and modeling of surgical site
CN102559190B (zh) 2012-01-12 2013-09-04 东南大学 一种双模式光学编码探针及其制备方法
US9561292B1 (en) 2012-08-20 2017-02-07 Duke University Nanostars and nanoconstructs for detection, imaging, and therapy
CA2882388C (en) 2012-08-31 2020-10-20 Sloan-Kettering Institute For Cancer Research Particles, methods and uses thereof
US9824440B2 (en) 2012-11-20 2017-11-21 Vanderbilt University Methods and systems for three-dimensional real-time intraoperative surgical margin evaluation of tumor tissues
WO2014089247A2 (en) 2012-12-04 2014-06-12 Sloan-Kettering Institute For Cancer Research Modular polymer hydrogel nanoparticles and methods of their manufacture
US10105456B2 (en) 2012-12-19 2018-10-23 Sloan-Kettering Institute For Cancer Research Multimodal particles, methods and uses thereof
GB201302886D0 (en) 2013-02-19 2013-04-03 Univ Singapore Diagnostic instrument and method
CN105122065B (zh) 2013-02-20 2018-05-25 康奈尔大学 多层荧光纳米颗粒及其制备和使用方法
CA2900686A1 (en) 2013-02-20 2014-08-28 Sloan-Kettering Institute For Cancer Research Wide field raman imaging apparatus and associated methods
US20140350534A1 (en) 2013-02-20 2014-11-27 Sloan-Kettering Institute For Cancer Research Raman based ablation/resection systems and methods
US10182757B2 (en) 2013-07-22 2019-01-22 The Rockefeller University System and method for optical detection of skin disease
US20170138860A1 (en) 2014-07-02 2017-05-18 National University Of Singapore Raman spectroscopy system, apparatus, and method for analyzing, characterizing, and/or diagnosing a type or nature of a sample or a tissue such as an abnormal growth
EP3182917A1 (en) 2014-08-20 2017-06-28 Memorial Sloan Kettering Cancer Center Raman-triggered ablation/resection systems and methods
WO2016149378A1 (en) 2015-03-16 2016-09-22 Pdx Pharmaceuticals, Llc Cross-linked polymer modified nanoparticles
US11172823B2 (en) 2015-03-17 2021-11-16 Synaptive Medical Inc. Method, system and apparatus for tracking surgical imaging devices
AU2016257431B2 (en) 2015-05-04 2021-08-05 Cornell University Ultrasmall nanoparticles and methods of making and using same
WO2018213851A1 (en) 2017-05-19 2018-11-22 Cornell University Functionalized nanoparticles and methods of making and using same

Also Published As

Publication number Publication date
EP2892352B1 (en) 2020-12-09
JP2015526527A (ja) 2015-09-10
EP2892352A4 (en) 2016-05-18
CA2882388A1 (en) 2014-03-06
CA2882388C (en) 2020-10-20
EP2892352A1 (en) 2015-07-15
AU2013308472A1 (en) 2015-03-05
AU2013308472B2 (en) 2017-05-25
JP6654897B2 (ja) 2020-02-26
CN104684398A (zh) 2015-06-03
JP2018165278A (ja) 2018-10-25
WO2014036470A1 (en) 2014-03-06
US10322194B2 (en) 2019-06-18
US20150258218A1 (en) 2015-09-17

Similar Documents

Publication Publication Date Title
HK1210913A1 (en) Particles, methods and uses thereof
HK1202545A1 (en) New diazaspirocycloalkane and azaspirocycloalkane
HK1199023A1 (en) Substituted benzothienylpyrrolotriazines and uses thereof
HK1200822A1 (en) Substituted dipyridylamines and uses thereof
HRP20190358T1 (hr) Antitijela protiv asic1 i njihova primjena
EP2809597A4 (en) SORTING SYSTEMS AND CORRESPONDING METHODS
IL237068A (en) 1,3-dioxanomorphides and 1,3-dioxanocodides
HK1216143A1 (zh) 多模態粒子、其方法和用途
HK1210949A1 (en) Combinations and uses thereof
IL233781A0 (en) Antibodies against big-endothelin-1 and their uses
EP2920588A4 (en) TRACER PARTICLES AND METHOD FOR THE MANUFACTURE THEREOF
EP2837627A4 (en) AMIDOPYRIDINE DERIVATIVE AND USE THEREOF
GB201223330D0 (en) Products, methods and uses
HK1210809A1 (en) Beta-hexosyl-transferases and uses thereof
EP2867303A4 (en) PARTICLES OF THE SILSESQUIOXANE TYPE
EP2938415A4 (en) MATERIALS AND METHOD
IL237400B (en) Rhizobacteria and its uses
EP2900693A4 (en) ADCC-mediating antibodies, combinations and uses thereof
EP2925432A4 (en) SUPER-HYDROXYLATED ADSORBENTS AND USES THEREOF
GB201208372D0 (en) Antibodies and uses thereof