HK1210029A1 - Hydrochloride of 4-[[4-[[4-(2-cyanoethenyl)-2,6- dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile 4-[[4-[[4-(2-)-26-]]-2-]] - Google Patents

Hydrochloride of 4-[[4-[[4-(2-cyanoethenyl)-2,6- dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile 4-[[4-[[4-(2-)-26-]]-2-]]

Info

Publication number
HK1210029A1
HK1210029A1 HK15110805.7A HK15110805A HK1210029A1 HK 1210029 A1 HK1210029 A1 HK 1210029A1 HK 15110805 A HK15110805 A HK 15110805A HK 1210029 A1 HK1210029 A1 HK 1210029A1
Authority
HK
Hong Kong
Prior art keywords
amino
cyanoethenyl
benzonitrile
dimethylphenyl
pyrimidinyl
Prior art date
Application number
HK15110805.7A
Other languages
English (en)
Chinese (zh)
Inventor
Paul Theodoor Agnes Stevens
Jozef Peeters
Roger Petrus Gerebern Vandecruys
Alfred Elisabeth Stappers
Alex Herman Copmans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38091637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1210029(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from MYPI20043578A external-priority patent/MY169670A/en
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1210029A1 publication Critical patent/HK1210029A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Hybrid Cells (AREA)
HK15110805.7A 2004-09-02 2015-11-03 Hydrochloride of 4-[[4-[[4-(2-cyanoethenyl)-2,6- dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile 4-[[4-[[4-(2-)-26-]]-2-]] HK1210029A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
MYPI20043578A MY169670A (en) 2003-09-03 2004-09-02 Combinations of a pyrimidine containing nnrti with rt inhibitors
PCT/EP2004/052028 WO2005021001A1 (en) 2003-09-03 2004-09-03 Combinations of a pyrimidine containing nnrti with rt inhibitors
EP05101467 2005-02-25

Publications (1)

Publication Number Publication Date
HK1210029A1 true HK1210029A1 (en) 2016-04-15

Family

ID=38091637

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110805.7A HK1210029A1 (en) 2004-09-02 2015-11-03 Hydrochloride of 4-[[4-[[4-(2-cyanoethenyl)-2,6- dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile 4-[[4-[[4-(2-)-26-]]-2-]]

Country Status (21)

Country Link
EP (1) EP1632232B3 (sr)
JP (1) JP4912309B2 (sr)
CN (1) CN104586850A (sr)
AT (1) ATE508748T1 (sr)
BR (1) BRPI0514871A (sr)
CY (3) CY1112249T1 (sr)
DK (1) DK1632232T6 (sr)
EA (1) EA013686B1 (sr)
ES (1) ES2371442T7 (sr)
FR (2) FR16C1023I1 (sr)
HK (1) HK1210029A1 (sr)
HU (2) HUS1600061I1 (sr)
IL (1) IL181650A (sr)
LT (2) LTPA2016043I1 (sr)
ME (1) ME01246B (sr)
MX (1) MX2007002595A (sr)
NI (1) NI200700068A (sr)
NO (3) NO340654B1 (sr)
PT (1) PT1632232E (sr)
RS (1) RS51923B2 (sr)
SI (1) SI1632232T1 (sr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
SG170073A1 (en) * 2006-01-20 2011-04-29 Tibotec Pharm Ltd Long term treatment of hiv infection
TWI494133B (zh) 2007-03-14 2015-08-01 Tibotec Pharm Ltd 重組用粉末
UA114075C2 (xx) * 2010-11-19 2017-04-25 БАГАТОШАРОВА ТАБЛЕТКА, ЩО МІСТИТЬ РИЛПІВІРИН HCl, ЕМТРИЦИТАБІН І ТЕНОФОВІРУ ДИЗОПРОКСИЛФУМАРАТ
KR101879468B1 (ko) * 2011-04-15 2018-07-17 엠큐어 파마슈티컬즈 리미티드 릴피비린 중간체의 제조를 위한 공정
EP2628732A1 (en) * 2012-02-20 2013-08-21 Sandoz AG Novel crystalline form of rilpivirine hydrochloride
WO2013087794A1 (en) 2011-12-14 2013-06-20 Sandoz Ag Polymorph of rilpivirine hydrochloride and its use as antiviral
EP2604593A1 (en) 2011-12-14 2013-06-19 Sandoz AG Polymorph of Rilpivirine hydrochloride and its use as antiviral
WO2013153162A1 (en) * 2012-04-11 2013-10-17 Sandoz Ag Polymorph of rilpivirine hydrochloride
WO2013153161A2 (en) * 2012-04-11 2013-10-17 Sandoz Ag Novel polymorph of rilpivirine hydrochloride
CN103570688B (zh) * 2012-07-19 2016-06-08 中国科学院上海药物研究所 2，5-二氨甲基吡嗪类化合物、其药物组合物、制备方法和用途
GR1008965B (el) * 2015-12-02 2017-02-28 Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων Φαρμακευτικο σκευασμα που περιλαμβανει δαρουναβιρη και μεθοδος παρασκευης αυτου
RU2616267C1 (ru) * 2016-01-25 2017-04-13 Закрытое Акционерное Общество "БИОКОМ" Твердая лекарственная форма индинавира немедленного высвобождения и способ ее получения
SI3528791T1 (sl) * 2016-10-24 2024-04-30 Janssen Sciences Ireland Unlimited Company Disperzibilne sestave
CN114392241B (zh) * 2022-01-10 2023-07-25 安徽贝克生物制药有限公司 一种利匹韦林片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307543B1 (en) * 1998-09-10 2001-10-23 Silicon Image, Inc. Bi-directional data transfer using two pair of differential lines as a single additional differential pair
MY169670A (en) * 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
JP4822707B2 (ja) * 2002-08-09 2011-11-24 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ４−［［４−［［４−（２−シアノエテニル）−２，６−ジメチルフェニル］アミノ］−２−ピリミジニル］アミノ］ベンゾニトリルの製造方法
WO2004050068A1 (en) * 2002-11-29 2004-06-17 Janssen Pharmaceutica N.V. Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
AP2065A (en) * 2003-02-07 2009-11-26 Janssen Pharmaceutica Nv Pyrimidine derivatives for the prevention of HIV infection

Also Published As

Publication number Publication date
BRPI0514871A (pt) 2008-06-24
NO340654B1 (no) 2017-05-22
CY2016051I1 (el) 2017-07-12
LTPA2016042I1 (lt) 2017-01-10
NO20071745L (no) 2007-04-02
EP1632232A1 (en) 2006-03-08
LTPA2016043I1 (lt) 2017-01-10
HUS1600061I1 (hu) 2017-01-30
DK1632232T6 (da) 2022-04-19
EA013686B1 (ru) 2010-06-30
NI200700068A (es) 2016-09-29
NO2017063I1 (no) 2017-11-21
JP2008511592A (ja) 2008-04-17
IL181650A (en) 2012-08-30
ATE508748T1 (de) 2011-05-15
SI1632232T1 (sl) 2011-09-30
RS51923B (sr) 2012-02-29
FR16C1025I1 (fr) 2017-02-03
EA200700536A1 (ru) 2007-08-31
MX2007002595A (es) 2007-04-25
NO2017065I1 (no) 2017-11-21
CY2016050I1 (el) 2017-07-12
PT1632232E (pt) 2011-08-02
RS51923B2 (sr) 2022-05-31
FR16C1023I1 (fr) 2017-02-03
EP1632232B1 (en) 2011-05-11
HUS1600060I1 (hu) 2017-01-30
DK1632232T3 (da) 2011-08-22
CN104586850A (zh) 2015-05-06
CY1112249T1 (el) 2015-12-09
ME01246B (me) 2013-06-20
ES2371442T7 (es) 2022-05-12
EP1632232B3 (en) 2022-03-30
IL181650A0 (en) 2007-07-04
ES2371442T3 (es) 2012-01-02
JP4912309B2 (ja) 2012-04-11

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Publication Publication Date Title
HK1210029A1 (en) Hydrochloride of 4-[[4-[[4-(2-cyanoethenyl)-2,6- dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile 4-[[4-[[4-(2-)-26-]]-2-]]
HK1174922A1 (en) Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6- dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile 4-[[4-[[4-(2-)-2,6-]]-2-]]
NO2014031I1 (no) (E)-4-[[4-[[4-(2-cyanoetenyl)-2,6-dimetylfenyl]amino-2-pyrimidinyl]-amino]-benzonitril (Rilpivirie) samt enhver terapeutisk ekvivalent form derav som er beskyttet av det aktuelle patentet så som farmasøytisk akseptable salter av Rilpiverine innbefattende hydrokloridsaltet av Rilpivirine, og Temofovir disproksil (spesielt Tenofovir disproksil fumaratsalt).
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