HK1206358A1 - 用於製備吡唑甲酸衍生物的方法 - Google Patents

用於製備吡唑甲酸衍生物的方法

Info

Publication number
HK1206358A1
HK1206358A1 HK15107082.7A HK15107082A HK1206358A1 HK 1206358 A1 HK1206358 A1 HK 1206358A1 HK 15107082 A HK15107082 A HK 15107082A HK 1206358 A1 HK1206358 A1 HK 1206358A1
Authority
HK
Hong Kong
Prior art keywords
preparation
carboxylic acid
acid derivatives
pyrazole carboxylic
pyrazole
Prior art date
Application number
HK15107082.7A
Other languages
English (en)
Inventor
比約恩.巴特爾斯
弗里茨.布利斯
卡特里.格勒布科茨賓登
馬蒂亞斯.克爾納
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1206358A1 publication Critical patent/HK1206358A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/02Compounds containing any of the groups, e.g. carbazates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/02Compounds containing any of the groups, e.g. carbazates
    • C07C281/04Compounds containing any of the groups, e.g. carbazates the other nitrogen atom being further doubly-bound to a carbon atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK15107082.7A 2012-08-17 2015-07-24 用於製備吡唑甲酸衍生物的方法 HK1206358A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12180802 2012-08-17
PCT/EP2013/066953 WO2014027009A1 (en) 2012-08-17 2013-08-14 Process for the preparation of pyrazole carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
HK1206358A1 true HK1206358A1 (zh) 2016-01-08

Family

ID=46851296

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15107082.7A HK1206358A1 (zh) 2012-08-17 2015-07-24 用於製備吡唑甲酸衍生物的方法

Country Status (12)

Country Link
US (1) US9346763B2 (zh)
EP (1) EP2885276B1 (zh)
JP (1) JP6122118B2 (zh)
KR (1) KR20150042847A (zh)
CN (1) CN104540807B (zh)
BR (1) BR112015002779A2 (zh)
CA (1) CA2880846A1 (zh)
ES (1) ES2588056T3 (zh)
HK (1) HK1206358A1 (zh)
MX (1) MX348635B (zh)
RU (1) RU2638112C2 (zh)
WO (1) WO2014027009A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015164783A1 (en) 2014-04-25 2015-10-29 Bayer Medical Care Inc. Syringe with rolling diaphragm
ES2566228B1 (es) * 2014-09-11 2017-02-08 Consejo Superior De Investigaciones Cientificas Uso de ésteres derivados de pirazol protón-ionizables y sus correspondientes sales para el tratamiento de la enfermedad de Chagas y la leishmaniasis
CN104529899A (zh) * 2014-12-19 2015-04-22 浙江泰达作物科技有限公司 高区域选择性制备1-烷基-3-卤代烷基吡唑衍生物的方法
RU2718291C2 (ru) 2015-04-24 2020-04-01 БАЙЕР ХелсКер ЛЛСи Шприц с подворачивающейся мембраной
CA3036818C (en) 2016-09-16 2024-01-09 Bayer Healthcare Llc Pressure jacket having syringe retaining element
EP3525840B1 (en) 2016-10-17 2023-11-01 Bayer Healthcare LLC Fluid injector with syringe engagement mechanism
WO2018075386A1 (en) 2016-10-17 2018-04-26 Bayer Healthcare Llc Fluid injector with syringe engagement mechanism
CA3075481A1 (en) 2017-09-13 2019-03-21 Bayer Healthcare Llc Sliding syringe cap for separate filling and delivery
CN112912119A (zh) 2018-09-11 2021-06-04 拜耳医药保健有限责任公司 流体注入器系统的注射器固定特征
AU2020345829A1 (en) 2019-09-10 2022-03-17 Bayer Healthcare Llc Pressure jackets and syringe retention features for angiography fluid injectors
IL295316B1 (en) 2020-02-21 2024-08-01 Bayer Healthcare Llc Fluid path connectors for administering medical fluids
MX2022010694A (es) 2020-02-28 2022-09-26 Bayer Healthcare Llc Juego de mezcla de fluidos.
IL299062A (en) 2020-06-18 2023-02-01 Bayer Healthcare Llc Built-in air bubble suspension device for angiography syringe fluid paths
IL300292A (en) 2020-08-11 2023-04-01 Bayer Healthcare Llc Features for angiography syringe
WO2022119837A2 (en) 2020-12-01 2022-06-09 Bayer Healthcare Llc Cassette for retention of fluid path components for fluid injector system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2263999A4 (en) * 2008-03-18 2012-11-07 Mitsui Chemicals Agro Inc METHOD FOR PRODUCING A FLUOROUS ACYL ACIDIC ACID DERIVATIVE, METHOD FOR THE PRODUCTION OF A FLUOROUS PYRAZOL CARBOXYLIC ACID DERIVATIVE AND METHOD FOR PRODUCING A FLUOROUS PYRAZOL CARBOXYLENE DERIVATIVE
US8410117B2 (en) * 2010-03-26 2013-04-02 Hoffmann-La Roche Inc. Imidazopyrimidine derivatives

Also Published As

Publication number Publication date
EP2885276A1 (en) 2015-06-24
WO2014027009A1 (en) 2014-02-20
CN104540807B (zh) 2016-09-14
MX348635B (es) 2017-06-22
RU2638112C2 (ru) 2017-12-15
EP2885276B1 (en) 2016-06-01
JP2015530371A (ja) 2015-10-15
RU2015106856A (ru) 2016-10-10
JP6122118B2 (ja) 2017-04-26
US9346763B2 (en) 2016-05-24
CN104540807A (zh) 2015-04-22
BR112015002779A8 (pt) 2017-12-19
CA2880846A1 (en) 2014-02-20
US20150158818A1 (en) 2015-06-11
MX2015001023A (es) 2015-04-08
ES2588056T3 (es) 2016-10-28
BR112015002779A2 (pt) 2019-10-15
KR20150042847A (ko) 2015-04-21

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