HK1205939A1 - Parenteral formulations for administering macrolide antibiotics - Google Patents

Parenteral formulations for administering macrolide antibiotics

Info

Publication number
HK1205939A1
HK1205939A1 HK15106527.2A HK15106527A HK1205939A1 HK 1205939 A1 HK1205939 A1 HK 1205939A1 HK 15106527 A HK15106527 A HK 15106527A HK 1205939 A1 HK1205939 A1 HK 1205939A1
Authority
HK
Hong Kong
Prior art keywords
parenteral formulations
macrolide antibiotics
administering
administering macrolide
antibiotics
Prior art date
Application number
HK15106527.2A
Other languages
English (en)
Chinese (zh)
Inventor
David E Pereira
Sara Wu
Prabhavathi Fernandes
Original Assignee
Cempra Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cempra Pharmaceuticals Inc filed Critical Cempra Pharmaceuticals Inc
Publication of HK1205939A1 publication Critical patent/HK1205939A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
HK15106527.2A 2012-03-27 2015-07-08 Parenteral formulations for administering macrolide antibiotics HK1205939A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261616196P 2012-03-27 2012-03-27
US201361783026P 2013-03-14 2013-03-14
PCT/US2013/034179 WO2013148891A1 (fr) 2012-03-27 2013-03-27 Formulations parentérales pour l'administration d'antibiotiques macrolides

Publications (1)

Publication Number Publication Date
HK1205939A1 true HK1205939A1 (en) 2015-12-31

Family

ID=49261221

Family Applications (2)

Application Number Title Priority Date Filing Date
HK15106527.2A HK1205939A1 (en) 2012-03-27 2015-07-08 Parenteral formulations for administering macrolide antibiotics
HK15109278.7A HK1208622A1 (en) 2012-03-27 2015-09-22 Parenteral formulations for administering macrolide antibiotics

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK15109278.7A HK1208622A1 (en) 2012-03-27 2015-09-22 Parenteral formulations for administering macrolide antibiotics

Country Status (15)

Country Link
US (2) US10188674B2 (fr)
EP (1) EP2830632A4 (fr)
JP (2) JP6208742B2 (fr)
KR (1) KR20140139083A (fr)
CN (1) CN104470527B (fr)
AU (1) AU2013239696C1 (fr)
CA (1) CA2868262A1 (fr)
HK (2) HK1205939A1 (fr)
IL (2) IL234769A (fr)
IN (1) IN2014DN08939A (fr)
MX (1) MX2014011537A (fr)
NZ (1) NZ700182A (fr)
RU (1) RU2658050C2 (fr)
SG (1) SG11201405895UA (fr)
WO (1) WO2013148891A1 (fr)

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WO2004080391A2 (fr) 2003-03-10 2004-09-23 Optimer Pharmaceuticals, Inc. Nouveaux agents antibacteriens
US9453042B2 (en) 2007-10-25 2016-09-27 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
WO2010048600A1 (fr) 2008-10-24 2010-04-29 Cempra Pharmaceuticals, Inc. Procédés de traitement de maladies résistantes en utilisant des macrolides contenant du triazole
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
WO2011032052A1 (fr) 2009-09-10 2011-03-17 Cempra Pharmaceuticals, Inc. Méthodes de traitement du paludisme, de la tuberculose et des maladies à complexe mycobacterium avium (mac)
EP2571506B1 (fr) 2010-05-20 2017-05-10 Cempra Pharmaceuticals, Inc. Procédés de préparation de macrolides et de kétolides et d'intermédiaires de ceux-ci
WO2012034058A1 (fr) 2010-09-10 2012-03-15 Cempra Pharmaceuticals, Inc. Fluorocétolides formant des liaisons hydrogène pour traiter les maladies
RU2658050C2 (ru) 2012-03-27 2018-06-19 Семпра Фармасьютикалз, Инк. Парентеральные составы для введения макролидных антибиотиков
AU2014239959A1 (en) 2013-03-14 2015-10-01 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CA2908575C (fr) 2013-04-04 2021-11-16 President And Fellows Of Harvard College Macrolides et leurs procedes de preparation et d'utilisation
CN106998685A (zh) 2014-10-08 2017-08-01 哈佛大学的校长及成员们 14‑元酮内酯及其制备和使用方法
JP2018509452A (ja) 2015-03-25 2018-04-05 プレジデント アンド フェローズ オブ ハーバード カレッジ 修飾デソサミン糖をもつマクロライドおよびその使用
EP3582615A1 (fr) * 2017-02-17 2019-12-25 Cempra Pharmaceuticals, Inc. Macrolides contenant un triazole et utilisations ophtalmiques de ceux-ci
CN109394200B (zh) * 2018-12-16 2021-10-19 冯兴怀 用于液体治疗、容量管理的微循环脉冲血流监测系统和方法

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CA2868262A1 (fr) 2013-10-03
CN104470527A (zh) 2015-03-25
IN2014DN08939A (fr) 2015-05-22
IL254005A0 (en) 2017-10-31
KR20140139083A (ko) 2014-12-04
US20150342977A1 (en) 2015-12-03
EP2830632A4 (fr) 2015-10-21
CN104470527B (zh) 2019-05-28
WO2013148891A1 (fr) 2013-10-03
JP6208742B2 (ja) 2017-10-04
MX2014011537A (es) 2015-02-10
EP2830632A1 (fr) 2015-02-04
SG11201405895UA (en) 2014-10-30
US20190328759A1 (en) 2019-10-31
RU2014139169A (ru) 2016-05-20
HK1208622A1 (en) 2016-03-11
AU2013239696B2 (en) 2017-12-14
JP6378408B2 (ja) 2018-08-22
RU2658050C2 (ru) 2018-06-19
IL234769A (en) 2017-08-31
AU2013239696C1 (en) 2018-11-29
JP2015512413A (ja) 2015-04-27
AU2013239696A1 (en) 2014-10-09
IL254005B (en) 2019-09-26
US10188674B2 (en) 2019-01-29
NZ700182A (en) 2017-02-24

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