HK1202555A1 - Process for the manufacture of cyclic undecapeptides - Google Patents

Process for the manufacture of cyclic undecapeptides

Info

Publication number
HK1202555A1
HK1202555A1 HK15102858.0A HK15102858A HK1202555A1 HK 1202555 A1 HK1202555 A1 HK 1202555A1 HK 15102858 A HK15102858 A HK 15102858A HK 1202555 A1 HK1202555 A1 HK 1202555A1
Authority
HK
Hong Kong
Prior art keywords
manufacture
cyclic undecapeptides
undecapeptides
cyclic
Prior art date
Application number
HK15102858.0A
Other languages
English (en)
Chinese (zh)
Inventor
Fabrice Gallou
Bernard Riss
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48444372&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1202555(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1202555A1 publication Critical patent/HK1202555A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15102858.0A 2012-05-09 2015-03-20 Process for the manufacture of cyclic undecapeptides HK1202555A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261644616P 2012-05-09 2012-05-09
PCT/EP2013/059672 WO2013167703A1 (en) 2012-05-09 2013-05-08 Process for the manufacture of cyclic undecapeptides

Publications (1)

Publication Number Publication Date
HK1202555A1 true HK1202555A1 (en) 2015-10-02

Family

ID=48444372

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102858.0A HK1202555A1 (en) 2012-05-09 2015-03-20 Process for the manufacture of cyclic undecapeptides

Country Status (24)

Country Link
US (2) US20150087808A1 (es)
EP (1) EP2847211A1 (es)
JP (3) JP2015517481A (es)
KR (1) KR20150006435A (es)
CN (2) CN108715606A (es)
AR (1) AR090964A1 (es)
AU (2) AU2013257989A1 (es)
BR (1) BR112014027648A2 (es)
CA (1) CA2868940A1 (es)
CL (1) CL2014003014A1 (es)
CO (1) CO7141428A2 (es)
EA (1) EA024903B1 (es)
EC (1) ECSP14030537A (es)
HK (1) HK1202555A1 (es)
IL (1) IL235428A0 (es)
IN (1) IN2014DN08483A (es)
MA (1) MA20150231A1 (es)
MX (1) MX2014013613A (es)
PE (1) PE20142433A1 (es)
PH (1) PH12014502499A1 (es)
SG (1) SG11201406303XA (es)
TN (1) TN2014000411A1 (es)
TW (1) TW201350508A (es)
WO (1) WO2013167703A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105693820A (zh) * 2014-11-27 2016-06-22 武汉药明康德新药开发有限公司 一种降解环孢菌素a的方法
TWI780152B (zh) 2017-05-12 2022-10-11 日商中外製藥股份有限公司 環狀有機化合物的製造方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT401177B (de) 1993-10-22 1996-07-25 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3-cephem-4-carbonsäure-derivaten
JP4350898B2 (ja) * 1998-07-01 2009-10-21 デビオファーム・ソシエテ・アノニム 活性の特徴が改善された新規のシクロスポリン
ES2267492T3 (es) * 1999-02-05 2007-03-16 Debiopharm S.A. Derivados de ciclosporina y procedimiento de preparacion de dichos derivados.
US6995139B2 (en) * 2001-04-20 2006-02-07 Debiopharm S.A. Cyclic undecapeptide pro-drugs and uses thereof
NZ531944A (en) * 2001-10-19 2006-03-31 Isotechnika Inc Synthesis of cyclosporin analogs
TW200505946A (en) 2003-04-08 2005-02-16 Hoffmann La Roche Process for preparation of cyclosporin a analog
EP1793844B1 (en) * 2004-10-01 2010-12-08 Debiopharm S.A. Use of [d-meala]3-[etval]4-cyclosporin for the treatment of hepatitis c infection
WO2006063470A1 (en) * 2004-12-17 2006-06-22 Isotechnika Inc. Metabolites of cyclosporin analogs
JP5801534B2 (ja) 2007-01-04 2015-10-28 デビオファーム インターナショナル ソシエテ アノニム ウールリッヒ型先天筋ジストロフィーの処置のための、非免疫抑制性シクロスポリン
NZ584356A (en) 2007-09-26 2011-10-28 Univ Oregon Health & Science Cyclic undecapeptides and derivatives as multiple sclerosis therapies
US7910378B2 (en) * 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
WO2009098533A1 (en) 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy
AU2009312535B2 (en) 2008-11-06 2015-03-26 Debio Recherche Pharmaceutique S.A. Cycloundecadepsipeptide compounds and use of said compounds as a medicament
EP2376524B1 (en) * 2008-12-31 2017-03-15 Cypralis Limited Derivatives of cyclosporin a
NZ594755A (en) * 2009-01-30 2013-12-20 Enanta Pharm Inc Cyclosporin analogues for preventing or treating hepatitis c infection
WO2012021796A2 (en) * 2010-08-12 2012-02-16 S&T Global, Inc. Novel cyclosporin derivatives for the treatment and prevention of a viral infection

Also Published As

Publication number Publication date
EP2847211A1 (en) 2015-03-18
BR112014027648A2 (pt) 2017-06-27
WO2013167703A1 (en) 2013-11-14
CA2868940A1 (en) 2013-11-14
US20160304554A1 (en) 2016-10-20
US20150087808A1 (en) 2015-03-26
WO2013167703A9 (en) 2014-11-20
TW201350508A (zh) 2013-12-16
AR090964A1 (es) 2014-12-17
JP2015517481A (ja) 2015-06-22
US9840534B2 (en) 2017-12-12
SG11201406303XA (en) 2014-11-27
JP2018035154A (ja) 2018-03-08
EA201492036A1 (ru) 2015-02-27
PE20142433A1 (es) 2015-02-02
CN104284902A (zh) 2015-01-14
AU2016222370B2 (en) 2017-10-05
EA024903B1 (ru) 2016-10-31
MX2014013613A (es) 2015-02-12
CO7141428A2 (es) 2014-12-12
AU2013257989A1 (en) 2014-10-23
ECSP14030537A (es) 2015-09-30
CN108715606A (zh) 2018-10-30
AU2016222370A1 (en) 2016-09-15
PH12014502499A1 (en) 2014-12-22
KR20150006435A (ko) 2015-01-16
JP2020033349A (ja) 2020-03-05
IN2014DN08483A (es) 2015-05-08
TN2014000411A1 (en) 2015-12-21
MA20150231A1 (fr) 2015-07-31
CL2014003014A1 (es) 2015-03-06
IL235428A0 (en) 2014-12-31

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