HK1202555A1 - Process for the manufacture of cyclic undecapeptides - Google Patents

Process for the manufacture of cyclic undecapeptides

Info

Publication number
HK1202555A1
HK1202555A1 HK15102858.0A HK15102858A HK1202555A1 HK 1202555 A1 HK1202555 A1 HK 1202555A1 HK 15102858 A HK15102858 A HK 15102858A HK 1202555 A1 HK1202555 A1 HK 1202555A1
Authority
HK
Hong Kong
Prior art keywords
manufacture
cyclic undecapeptides
undecapeptides
cyclic
Prior art date
Application number
HK15102858.0A
Other languages
English (en)
Chinese (zh)
Inventor
Fabrice Gallou
Bernard Riss
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48444372&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1202555(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1202555A1 publication Critical patent/HK1202555A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK15102858.0A 2012-05-09 2015-03-20 Process for the manufacture of cyclic undecapeptides HK1202555A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261644616P 2012-05-09 2012-05-09
PCT/EP2013/059672 WO2013167703A1 (en) 2012-05-09 2013-05-08 Process for the manufacture of cyclic undecapeptides

Publications (1)

Publication Number Publication Date
HK1202555A1 true HK1202555A1 (en) 2015-10-02

Family

ID=48444372

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15102858.0A HK1202555A1 (en) 2012-05-09 2015-03-20 Process for the manufacture of cyclic undecapeptides

Country Status (24)

Country Link
US (2) US20150087808A1 (xx)
EP (1) EP2847211A1 (xx)
JP (3) JP2015517481A (xx)
KR (1) KR20150006435A (xx)
CN (2) CN104284902A (xx)
AR (1) AR090964A1 (xx)
AU (2) AU2013257989A1 (xx)
BR (1) BR112014027648A2 (xx)
CA (1) CA2868940A1 (xx)
CL (1) CL2014003014A1 (xx)
CO (1) CO7141428A2 (xx)
EA (1) EA024903B1 (xx)
EC (1) ECSP14030537A (xx)
HK (1) HK1202555A1 (xx)
IL (1) IL235428A0 (xx)
IN (1) IN2014DN08483A (xx)
MA (1) MA20150231A1 (xx)
MX (1) MX2014013613A (xx)
PE (1) PE20142433A1 (xx)
PH (1) PH12014502499A1 (xx)
SG (1) SG11201406303XA (xx)
TN (1) TN2014000411A1 (xx)
TW (1) TW201350508A (xx)
WO (1) WO2013167703A1 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105693820A (zh) * 2014-11-27 2016-06-22 武汉药明康德新药开发有限公司 一种降解环孢菌素a的方法
CN110799523A (zh) 2017-05-12 2020-02-14 中外制药株式会社 用于制备环状有机化合物的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT401177B (de) 1993-10-22 1996-07-25 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3-cephem-4-carbonsäure-derivaten
CN1218958C (zh) * 1998-07-01 2005-09-14 德比奥药物股份有限公司 活性范围改善的环孢菌素
US6790935B1 (en) * 1999-02-05 2004-09-14 Debiopharm S.A. Cyclosporin derivatives and method for the production of said derivatives
RU2290196C2 (ru) * 2001-04-20 2006-12-27 Дебиофарм С.А. Модифицированный циклоспорин, который можно использовать в качестве пролекарства, и его применение
CA2461740C (en) * 2001-10-19 2013-02-12 Isotechnika Inc. Synthesis of cyclosporin analogs
TW200505946A (en) 2003-04-08 2005-02-16 Hoffmann La Roche Process for preparation of cyclosporin a analog
JP4892486B2 (ja) * 2004-10-01 2012-03-07 デビオファーム ソシエテ アノニム C型肝炎感染の治療のための[d−meala]3−[etval]4−シクロスポリンの使用、及び当該[d−meala]3−[etval]4−シクロスポリンを含む医薬組成物
TW200635954A (en) * 2004-12-17 2006-10-16 Isotechnika Inc Metabolites of cyclosporin analogs
EP2124992A2 (en) 2007-01-04 2009-12-02 Debiopharm S.A. Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy
NZ584356A (en) 2007-09-26 2011-10-28 Univ Oregon Health & Science Cyclic undecapeptides and derivatives as multiple sclerosis therapies
US7910378B2 (en) * 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
WO2009098533A1 (en) 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy
WO2010052559A1 (en) 2008-11-06 2010-05-14 Debio Recherche Pharmaceutique S.A. Cycloundecadepsipeptide compounds and use of said compounds as a medicament
US8536114B2 (en) * 2008-12-31 2013-09-17 Scynexis, Inc. Macrocycles
CA2751210C (en) * 2009-01-30 2015-04-21 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis c infection
WO2012021796A2 (en) * 2010-08-12 2012-02-16 S&T Global, Inc. Novel cyclosporin derivatives for the treatment and prevention of a viral infection

Also Published As

Publication number Publication date
AR090964A1 (es) 2014-12-17
US9840534B2 (en) 2017-12-12
SG11201406303XA (en) 2014-11-27
TW201350508A (zh) 2013-12-16
CL2014003014A1 (es) 2015-03-06
JP2015517481A (ja) 2015-06-22
AU2016222370B2 (en) 2017-10-05
US20150087808A1 (en) 2015-03-26
AU2016222370A1 (en) 2016-09-15
JP2018035154A (ja) 2018-03-08
TN2014000411A1 (en) 2015-12-21
ECSP14030537A (es) 2015-09-30
US20160304554A1 (en) 2016-10-20
AU2013257989A1 (en) 2014-10-23
EA024903B1 (ru) 2016-10-31
WO2013167703A9 (en) 2014-11-20
WO2013167703A1 (en) 2013-11-14
KR20150006435A (ko) 2015-01-16
CN104284902A (zh) 2015-01-14
MX2014013613A (es) 2015-02-12
CA2868940A1 (en) 2013-11-14
EA201492036A1 (ru) 2015-02-27
EP2847211A1 (en) 2015-03-18
PH12014502499A1 (en) 2014-12-22
BR112014027648A2 (pt) 2017-06-27
MA20150231A1 (fr) 2015-07-31
CO7141428A2 (es) 2014-12-12
JP2020033349A (ja) 2020-03-05
PE20142433A1 (es) 2015-02-02
IN2014DN08483A (xx) 2015-05-08
IL235428A0 (en) 2014-12-31
CN108715606A (zh) 2018-10-30

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