HK1198691A1 - Drug delivery from embolic agents - Google Patents

Drug delivery from embolic agents

Info

Publication number
HK1198691A1
HK1198691A1 HK14112213.0A HK14112213A HK1198691A1 HK 1198691 A1 HK1198691 A1 HK 1198691A1 HK 14112213 A HK14112213 A HK 14112213A HK 1198691 A1 HK1198691 A1 HK 1198691A1
Authority
HK
Hong Kong
Prior art keywords
drug delivery
anionic
ethylenically unsaturated
polyvinylalcohol
crosslinked
Prior art date
Application number
HK14112213.0A
Other languages
English (en)
Chinese (zh)
Inventor
Andrew Lennard Lewis
Peter William Stratford
Maria Victoria Gonzalez-Fajardo
Yiqing Tang
Original Assignee
Biocompatibles Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocompatibles Uk Ltd filed Critical Biocompatibles Uk Ltd
Publication of HK1198691A1 publication Critical patent/HK1198691A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A61L2300/434—Inhibitors, antagonists of enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622—Microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
HK14112213.0A 2004-09-07 2014-12-04 Drug delivery from embolic agents HK1198691A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04255411 2004-09-07

Publications (1)

Publication Number Publication Date
HK1198691A1 true HK1198691A1 (en) 2015-05-29

Family

ID=34930630

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14112213.0A HK1198691A1 (en) 2004-09-07 2014-12-04 Drug delivery from embolic agents

Country Status (11)

Country Link
US (3) US20070275991A1 (ko)
EP (3) EP3085361A1 (ko)
JP (4) JP5221134B2 (ko)
CN (2) CN101052378A (ko)
AT (1) ATE505185T1 (ko)
AU (1) AU2005281483B2 (ko)
CA (1) CA2579533C (ko)
DE (1) DE602005027477D1 (ko)
ES (1) ES2361919T3 (ko)
HK (1) HK1198691A1 (ko)
WO (1) WO2006027567A2 (ko)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE01918975T1 (de) 2000-03-24 2006-04-13 Biosphere Medical, Inc., Rockland Mikrokügelchen zur aktiven Embolisierung
WO2006013376A2 (en) * 2004-08-04 2006-02-09 Biocompatibles Uk Limited Drug delivery of a cox inhibitor from embolic agents
EP1879554B2 (en) 2005-05-09 2018-03-07 Biosphere Medical, S.A. Compositions and methods using microspheres and non-ionic contrast agents
PT2034951E (pt) * 2006-06-22 2013-04-18 Biocompatibles Uk Ltd Produto farmacêutico reidratável
EP1985286A1 (en) 2007-04-24 2008-10-29 Biocompatibles UK Limited Microspheres for treatment of brain tumours
EP2190409B9 (en) * 2007-08-16 2019-03-06 Biocompatibles UK Limited Delivery of drug combinations
WO2010063630A2 (en) * 2008-12-02 2010-06-10 Biocompatibles Uk Limited Pancreatic tumour treatment
JP6038801B2 (ja) * 2010-11-29 2016-12-07 セントレ ホスピタリエ ユニヴェルシテール ヴォードワ 抗血管新生薬を含む化学塞栓療法組成物
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
CN102336904B (zh) * 2011-09-29 2013-03-27 成都一平医药科技发展有限公司 一种喜树碱及其衍生物的多价peg修饰物及其用途
CN102397593B (zh) * 2011-11-11 2013-12-18 北京大学 X线下可显影的栓塞微粒及其制备方法和应用
PT2921166T (pt) * 2012-11-15 2017-09-19 Utah-Inha Dds & Advanced Therapeutics Res Center Micropérolas biodegradáveis com capacidade de adsorção de fármacos anticancro melhorada, contendo albumina e sulfato de dextrano, e seu processo de preparação
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
JP6049901B2 (ja) 2012-11-27 2016-12-21 ユタ−イナ ディーディーエス アンド アドバンスト セラピューティクス リサーチ センター 陰イオン性高分子を含む抗癌剤吸着能力の向上された生分解性マイクロビーズ及びその製造方法
BR112016005770B1 (pt) 2013-09-19 2021-07-27 Terumo Corporation Partículas de polímero
CA2923741C (en) 2013-09-19 2022-06-07 Microvention, Inc. Polymer films
KR102287781B1 (ko) 2013-11-08 2021-08-06 테루모 가부시키가이샤 중합체 입자
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
JP2016124818A (ja) * 2014-12-26 2016-07-11 日本化薬株式会社 転移性肝癌治療薬及び転移性肝癌の治療方法
US9907880B2 (en) 2015-03-26 2018-03-06 Microvention, Inc. Particles
WO2016203337A2 (en) * 2015-06-14 2016-12-22 Mohan M Alapati Compositions and methods for the treatment of cancer
WO2016203352A2 (en) * 2015-06-14 2016-12-22 Mohan M Alapati Compositions and methods for the treatment of cancer
GB201515602D0 (en) 2015-09-03 2015-10-21 Biocompatibles Uk Ltd Polymers and microspheres
CA3038642C (en) 2016-09-28 2021-11-02 Terumo Corporation Polymer particles comprising polymerizable pharmaceutical agents
US11712418B2 (en) 2017-05-26 2023-08-01 Bruin Biosciences, Inc. Chemoembolization agents
CN107812232A (zh) * 2017-11-08 2018-03-20 华威（深圳）医疗器械有限责任公司 可显影羧基改性聚乙烯醇微球栓塞剂及其制备工艺
JP7198529B2 (ja) * 2018-11-30 2023-01-04 ネクストバイオメディカル カンパニー リミテッド 生分解性高分子を含む化学塞栓用水和ゲル粒子
JP7275694B2 (ja) 2019-03-18 2023-05-18 株式会社リコー 感熱記録媒体、及び物品
GB201918300D0 (en) * 2019-12-12 2020-01-29 Extruded Pharmaceuticals Ltd Chemotherapeutic drug implant

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4032561A (en) * 1975-05-27 1977-06-28 The Upjohn Company 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF1.sub.α compounds
US4224427A (en) 1978-06-01 1980-09-23 Ciba-Geigy Corporation Process for preparing hydrogels as spherical beads of large size
JPS6019790A (ja) 1983-07-14 1985-01-31 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
US4978713A (en) 1987-12-16 1990-12-18 Ciba-Geigy Corporation Polyvinyl alcohol derivatives containing pendant vinylic monomer reaction product units bound through ether groups and hydrogel contact lenses made therefrom
GB9023498D0 (en) 1990-10-29 1990-12-12 Biocompatibles Ltd Soft contact lens material
US5559235A (en) * 1991-10-29 1996-09-24 Glaxo Wellcome Inc. Water soluble camptothecin derivatives
GB9301701D0 (en) 1993-01-28 1993-03-17 Biocompatibles Ltd New zwitterionic materials
GB9301702D0 (en) 1993-01-28 1993-03-17 Biocompatibles Ltd New materials
TW272976B (ko) 1993-08-06 1996-03-21 Ciba Geigy Ag
GB9415926D0 (en) 1994-08-04 1994-09-28 Biocompatibles Ltd New materials
CA2192725C (en) * 1995-12-28 2004-04-20 Kenji Tsujihara Camptothecin derivatives
WO2000029481A1 (en) 1998-11-13 2000-05-25 Biocompatibles Limited Anionic-cationic polyion complexes comprising zwitterionic monomer component
US6958212B1 (en) * 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
DE19905639A1 (de) * 1999-02-11 2000-08-17 Clariant Gmbh Wasserlösliche oder wasserquellbare Polymerisate
FR2793684B1 (fr) 1999-05-17 2001-08-10 Ethypharm Lab Prod Ethiques Utilisation de microspheres biodegradables liberant un agent anticancereux pour le traitement du glioblastome, procede de preparation de ces microspheres et suspension les contenant
US6191119B1 (en) * 1999-10-15 2001-02-20 Supergen, Inc. Combination therapy including 9-nitro-20(S)-camptothecin
JP2002154963A (ja) * 2000-11-14 2002-05-28 Yakult Honsha Co Ltd 徐放性抗腫瘍剤
US7838699B2 (en) * 2002-05-08 2010-11-23 Biosphere Medical Embolization using degradable crosslinked hydrogels
DE10230991A1 (de) 2002-07-10 2004-02-12 Robert Bosch Gmbh Werkzeugaufnahme für eine Werkzeugmaschine
US20040076582A1 (en) * 2002-08-30 2004-04-22 Dimatteo Kristian Agent delivery particle
KR101157260B1 (ko) * 2003-02-12 2012-06-15 바이오컴페터블즈 유케이 리미티드 고형 종양의 화학색전술용 조성물
US20040161466A1 (en) * 2003-02-14 2004-08-19 Biocompatibles Uk Limited Chemoembolisation

Also Published As

Publication number Publication date
JP2008512370A (ja) 2008-04-24
JP5792691B2 (ja) 2015-10-14
ATE505185T1 (de) 2011-04-15
AU2005281483B2 (en) 2008-11-27
EP1796644A2 (en) 2007-06-20
ES2361919T3 (es) 2011-06-24
JP5221134B2 (ja) 2013-06-26
EP2269580A2 (en) 2011-01-05
EP3085361A1 (en) 2016-10-26
CA2579533C (en) 2013-05-21
WO2006027567A3 (en) 2006-05-18
US20120276151A1 (en) 2012-11-01
JP2015180625A (ja) 2015-10-15
US20120201867A1 (en) 2012-08-09
AU2005281483A1 (en) 2006-03-16
JP2017025071A (ja) 2017-02-02
US20070275991A1 (en) 2007-11-29
WO2006027567A2 (en) 2006-03-16
EP2269580A3 (en) 2011-11-09
CN101052378A (zh) 2007-10-10
CA2579533A1 (en) 2006-03-16
JP2012236840A (ja) 2012-12-06
EP1796644B1 (en) 2011-04-13
CN103860479A (zh) 2014-06-18
DE602005027477D1 (de) 2011-05-26

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