HK1194922A1 - Inhibitors of poly(adp-ribose)polymerase (adp-) - Google Patents

Inhibitors of poly(adp-ribose)polymerase (adp-)

Info

Publication number
HK1194922A1
HK1194922A1 HK14108469.9A HK14108469A HK1194922A1 HK 1194922 A1 HK1194922 A1 HK 1194922A1 HK 14108469 A HK14108469 A HK 14108469A HK 1194922 A1 HK1194922 A1 HK 1194922A1
Authority
HK
Hong Kong
Prior art keywords
adp
ribose
polymerase
inhibitors
poly
Prior art date
Application number
HK14108469.9A
Other languages
English (en)
Chinese (zh)
Inventor
Viraj B Gandhi
Vincent L Giranda
Jianchun Gong
Thomas D Penning
Gui-Dong Zhu
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39584870&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1194922(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of HK1194922A1 publication Critical patent/HK1194922A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/58—1,2-Diazines; Hydrogenated 1,2-diazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Environmental Sciences (AREA)
  • Hematology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK14108469.9A 2006-12-28 2014-08-19 Inhibitors of poly(adp-ribose)polymerase (adp-) HK1194922A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88231706P 2006-12-28 2006-12-28

Publications (1)

Publication Number Publication Date
HK1194922A1 true HK1194922A1 (en) 2014-10-31

Family

ID=39584870

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14108469.9A HK1194922A1 (en) 2006-12-28 2014-08-19 Inhibitors of poly(adp-ribose)polymerase (adp-)

Country Status (31)

Country Link
US (1) US20080161280A1 (ru)
EP (2) EP2120579B1 (ru)
JP (2) JP5523837B2 (ru)
KR (2) KR101491998B1 (ru)
CN (2) CN101641014B (ru)
AU (1) AU2007340020B2 (ru)
BR (1) BRPI0722070A2 (ru)
CA (1) CA2672868C (ru)
CO (1) CO6220961A2 (ru)
CR (1) CR10901A (ru)
DK (2) DK2698062T3 (ru)
DO (1) DOP2009000159A (ru)
EC (1) ECSP099530A (ru)
ES (2) ES2442496T3 (ru)
GT (1) GT200900182A (ru)
HK (1) HK1194922A1 (ru)
HR (1) HRP20140115T1 (ru)
HU (1) HUE027641T2 (ru)
MX (2) MX347085B (ru)
MY (2) MY190838A (ru)
NO (1) NO20092698L (ru)
NZ (2) NZ598352A (ru)
PL (2) PL2120579T3 (ru)
PT (2) PT2698062E (ru)
RS (1) RS53196B (ru)
RU (1) RU2455286C2 (ru)
SG (2) SG2014013411A (ru)
SI (2) SI2698062T1 (ru)
TW (1) TWI429438B (ru)
UA (1) UA97506C2 (ru)
WO (1) WO2008083027A1 (ru)

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US8466150B2 (en) * 2006-12-28 2013-06-18 Abbott Laboratories Inhibitors of poly(ADP-ribose)polymerase
US20080280910A1 (en) * 2007-03-22 2008-11-13 Keith Allan Menear Phthalazinone derivatives
US8653262B2 (en) 2007-05-31 2014-02-18 Boehringer Ingelheim International Gmbh CCR2 receptor antagonists and uses thereof
US20090023727A1 (en) 2007-07-05 2009-01-22 Muhammad Hashim Javaid Phthalazinone derivatives
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Also Published As

Publication number Publication date
GT200900182A (es) 2010-02-19
PT2120579E (pt) 2014-02-17
KR101491998B1 (ko) 2015-02-10
ES2442496T3 (es) 2014-02-11
KR20140056395A (ko) 2014-05-09
AU2007340020A1 (en) 2008-07-10
EP2120579A1 (en) 2009-11-25
TW200840579A (en) 2008-10-16
UA97506C2 (en) 2012-02-27
SI2698062T1 (sl) 2015-12-31
RU2455286C2 (ru) 2012-07-10
ECSP099530A (es) 2009-08-28
EP2698062B1 (en) 2015-06-24
CR10901A (es) 2009-07-23
DOP2009000159A (es) 2015-11-30
WO2008083027A1 (en) 2008-07-10
RU2009128984A (ru) 2011-02-10
JP2014001209A (ja) 2014-01-09
EP2698062A1 (en) 2014-02-19
MX2009007051A (es) 2009-07-10
SG2014013411A (en) 2014-07-30
DK2698062T3 (en) 2015-09-14
KR20090094116A (ko) 2009-09-03
NZ577348A (en) 2012-04-27
BRPI0722070A2 (pt) 2014-04-08
ES2548353T3 (es) 2015-10-15
CN101641014B (zh) 2013-12-18
NO20092698L (no) 2009-09-28
RS53196B (en) 2014-06-30
EP2120579A4 (en) 2011-04-27
PT2698062E (pt) 2015-10-19
NZ598352A (en) 2013-08-30
EP2120579B1 (en) 2013-11-13
JP5523837B2 (ja) 2014-06-18
CA2672868A1 (en) 2008-07-10
HRP20140115T1 (hr) 2014-03-14
CA2672868C (en) 2015-11-24
US20080161280A1 (en) 2008-07-03
TWI429438B (zh) 2014-03-11
CN103690542A (zh) 2014-04-02
MX347085B (es) 2017-04-06
DK2120579T3 (da) 2014-02-03
MY165570A (en) 2018-04-05
PL2120579T3 (pl) 2014-04-30
CN103690542B (zh) 2015-11-18
KR101449436B1 (ko) 2014-10-14
SI2120579T1 (sl) 2014-03-31
CO6220961A2 (es) 2010-11-19
AU2007340020B2 (en) 2013-06-20
HUE027641T2 (en) 2016-11-28
JP2010514785A (ja) 2010-05-06
CN101641014A (zh) 2010-02-03
MY190838A (en) 2022-05-12
PL2698062T3 (pl) 2015-12-31
SG193664A1 (en) 2013-10-30

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