HK1181697A1 - Microfluidic device and method for fluid clotting time determination - Google Patents

Microfluidic device and method for fluid clotting time determination

Info

Publication number
HK1181697A1
HK1181697A1 HK13108976.6A HK13108976A HK1181697A1 HK 1181697 A1 HK1181697 A1 HK 1181697A1 HK 13108976 A HK13108976 A HK 13108976A HK 1181697 A1 HK1181697 A1 HK 1181697A1
Authority
HK
Hong Kong
Prior art keywords
clotting time
microfluidic device
time determination
fluid
fluid clotting
Prior art date
Application number
HK13108976.6A
Other languages
English (en)
Chinese (zh)
Inventor
艾納其．薩達巴查姆皮蒂爾德瑞比斯
胡安．安東尼奧．配昂埃奎厄恩
Original Assignee
艾萊恩微觀系統有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 艾萊恩微觀系統有限公司 filed Critical 艾萊恩微觀系統有限公司
Publication of HK1181697A1 publication Critical patent/HK1181697A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1002—Methods of surface bonding and/or assembly therefor with permanent bending or reshaping or surface deformation of self sustaining lamina
    • Y10T156/1039—Surface deformation only of sandwich or lamina [e.g., embossed panels]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Quality & Reliability (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Reciprocating Pumps (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK13108976.6A 2007-09-20 2013-08-01 Microfluidic device and method for fluid clotting time determination HK1181697A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07380258A EP2040073A1 (en) 2007-09-20 2007-09-20 Microfluidic device and method for fluid clotting time determination

Publications (1)

Publication Number Publication Date
HK1181697A1 true HK1181697A1 (en) 2013-11-15

Family

ID=39135160

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13108976.6A HK1181697A1 (en) 2007-09-20 2013-08-01 Microfluidic device and method for fluid clotting time determination

Country Status (23)

Country Link
US (2) US8961903B2 (ru)
EP (3) EP2040073A1 (ru)
JP (2) JP5579607B2 (ru)
KR (2) KR101439404B1 (ru)
CN (2) CN103143405B (ru)
AT (1) ATE504832T1 (ru)
AU (1) AU2008300501B2 (ru)
BR (2) BR122013004885B8 (ru)
CA (2) CA2803927C (ru)
DE (1) DE602008006108D1 (ru)
DK (1) DK2201365T3 (ru)
ES (1) ES2364568T3 (ru)
HK (1) HK1181697A1 (ru)
HR (1) HRP20110399T1 (ru)
IL (2) IL204571A (ru)
MX (1) MX2010003037A (ru)
NZ (2) NZ584208A (ru)
PL (1) PL2201365T3 (ru)
PT (1) PT2201365E (ru)
RU (2) RU2477480C2 (ru)
SI (1) SI2201365T1 (ru)
WO (1) WO2009037361A1 (ru)
ZA (2) ZA201001950B (ru)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2040073A1 (en) 2007-09-20 2009-03-25 Iline Microsystems, S.L. Microfluidic device and method for fluid clotting time determination
WO2009149257A1 (en) 2008-06-04 2009-12-10 The University Of Chicago The chemistrode: a plug-based microfluidic device and method for stimulation and sampling with high temporal, spatial, and chemical resolution
CA2730000A1 (en) * 2008-08-06 2010-02-11 F. Hoffmann La-Roche Ag Medical system comprising a compact barcode reader for consumable items
EP2414685A1 (en) * 2009-03-30 2012-02-08 Trustees of Boston University Reservoir-buffered mixers and remote valve switching for microfluidic devices
WO2010120786A1 (en) * 2009-04-13 2010-10-21 Micronics, Inc. Microfluidic clinical analyzer
WO2010122158A1 (en) * 2009-04-23 2010-10-28 Dublin City University A lateral flow assay device for coagulation monitoring and method thereof
BRPI1106097A2 (pt) * 2010-01-24 2017-06-27 Inst Chemy Fizycznej Polskiej Akademi Nauk sistema e método para produção e manipulação automazitada de misturas liquidas
WO2011094577A2 (en) 2010-01-29 2011-08-04 Micronics, Inc. Sample-to-answer microfluidic cartridge
EP3002591B1 (en) * 2010-03-30 2020-05-06 C A Casyso AG Composition for the determination of coagulation characteristics of a test liquid
JP5592144B2 (ja) * 2010-04-27 2014-09-17 日本電信電話株式会社 凝固活性測定装置および測定方法
EP2596347B1 (en) 2010-07-22 2017-09-06 Hach Company Alkalinity analysis using a lab-on-a-chip
EP2490020A1 (en) * 2011-02-18 2012-08-22 Koninklijke Philips Electronics N.V. Measurement chip, microfluidic device and method of measurement chip manufacture
DE102011004805A1 (de) * 2011-02-28 2012-08-30 Siemens Aktiengesellschaft Miniaturisierte magnetische Durchflusszytometrie
GB201109203D0 (en) * 2011-06-01 2011-07-13 Carclo Technical Plastics Ltd Fluid flow control
FI124169B (fi) * 2011-06-14 2014-04-15 Sandvik Mining & Constr Oy Menetelmä poraussuunnitelman laatimiseksi
CN103562716B (zh) * 2011-07-28 2016-06-01 京瓷株式会社 生物传感器
KR101193566B1 (ko) 2011-08-10 2012-10-22 고려대학교 산학협력단 마이크로칩 기반 혈소판 복합기능 검사 장치
GB201113992D0 (en) * 2011-08-12 2011-09-28 Molecular Vision Ltd Device
JP5592324B2 (ja) * 2011-09-05 2014-09-17 日本電信電話株式会社 凝固活性測定装置および測定方法
JP5607593B2 (ja) * 2011-09-05 2014-10-15 日本電信電話株式会社 凝固活性測定装置、測定チップおよび測定方法
US9429563B2 (en) * 2011-12-06 2016-08-30 Medtronic, Inc. Multi-zone falling washer blood clot detection
WO2013109549A2 (en) 2012-01-16 2013-07-25 Abram Scientific, Inc. Methods, devices, and systems for measuring physical properties of fluid
US9914120B2 (en) 2012-03-12 2018-03-13 Biosurfit S.A. Blood cell counting device and method
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
US9709579B2 (en) * 2012-06-27 2017-07-18 Colorado School Of Mines Microfluidic flow assay and methods of use
US9291612B2 (en) * 2012-07-16 2016-03-22 Micropoint Bioscience, Inc. Determining blood coagulation characteristics using residual accumulative conductive energy
CN104704357A (zh) * 2012-07-30 2015-06-10 加利福尼亚大学董事会 生物分子检测的测试条设计
EA021562B1 (ru) * 2012-08-15 2015-07-30 Общество С Ограниченной Ответственностью "Гематологическая Корпорация" Устройство мониторинга пространственного свертывания крови и ее компонентов
JP6010434B2 (ja) * 2012-11-15 2016-10-19 株式会社オーイーエムシステム 体液成分分析装置および体液成分分析方法
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument
HU1200732D0 (hu) * 2012-12-14 2014-06-30 Haemoglobal Ltd Egyszer használatos IVD eszköz a véralvadást jellemzõ INR érték otthoni ellenõrzõ méréséhez
CN104919035B (zh) 2012-12-21 2017-08-11 精密公司 便携式荧光检测系统和微测定盒
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
US9297816B1 (en) 2012-12-21 2016-03-29 University Of South Florida Devices and methods for measuring blood coagulation
JP6935167B2 (ja) 2012-12-21 2021-09-15 ペルキネルマー ヘルス サイエンシーズ， インコーポレイテッド マイクロ流体使用のための低弾性フィルム
JP6429794B2 (ja) 2013-01-03 2018-11-28 ブリガム・アンド・ウイミンズ・ホスピタル・インコーポレイテッド バイオミメティック流体プロセスの系および方法
JP6093950B2 (ja) * 2013-04-26 2017-03-15 東洋インキＳｃホールディングス株式会社 液体分析部材用粘着シートおよび液体分析部材
JP6484222B2 (ja) 2013-05-07 2019-03-13 マイクロニクス， インコーポレイテッド 核酸の調製および分析のためのデバイス
WO2014182831A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
US9651567B2 (en) 2013-05-14 2017-05-16 Cgt Enterprises, Llc Test strips for determining coagulation factor activities
JP6034238B2 (ja) * 2013-05-17 2016-11-30 日本電信電話株式会社 血液凝固検査方法
US10114032B2 (en) 2013-05-23 2018-10-30 Nippon Telegraph And Telephone Corporation Blood coagulation test method
US9562914B2 (en) * 2013-10-16 2017-02-07 President And Fellows Of Harvard College Microfluidic device for real-time clinical monitoring and quantitative assessment of whole blood coagulation
US10590373B2 (en) 2014-03-31 2020-03-17 Brigham And Women's Hospital, Inc. Systems and methods for biomimetic fluid processing
WO2015156322A1 (ja) * 2014-04-08 2015-10-15 藤森工業株式会社 血液性状検査用マイクロチップおよび血液性状検査用装置
WO2015173916A1 (ja) * 2014-05-14 2015-11-19 株式会社オーイーエムシステム 体液成分分析装置および体液成分分析方法
EP3154691B1 (en) * 2014-06-16 2022-06-29 Siemens Healthineers Nederland B.V. Cartridge for fast sample intake
CN107076733B (zh) 2014-09-09 2021-04-30 佩罗斯芬尔技术有限公司 基于微流控芯片的通用凝血测定
WO2016043903A1 (en) * 2014-09-15 2016-03-24 The University Of North Carolina At Chapel Hill Method for the assembly of functional thermoplastic nanofluidic devices
AU2015380619B2 (en) * 2015-01-30 2020-05-21 Hewlett-Packard Development Company, L.P. Microfluidic chip for coagulation sensing
EP3279310B1 (en) 2015-04-03 2021-05-05 National Institute of Advanced Industrial Science and Technology Cell culture apparatus and cell culture method
US9891209B2 (en) 2015-05-29 2018-02-13 C A Casyso Gmbh Electrode assembly for measurement of platelet function in whole blood
KR20190057444A (ko) 2015-08-10 2019-05-28 에센릭스 코프. 단계 간단화, 소량 샘플, 속도 가속화, 사용이 용이한 생물화학 측정장치 및 방법
KR101712429B1 (ko) * 2015-09-24 2017-03-08 대한민국(관리부서 질병관리본부장) 표면-증강 라만 산란 기반의 탄저균 검출용 미세유체칩 및 이를 이용한 탄저균 검출 방법
KR101787407B1 (ko) 2015-09-30 2017-10-18 명지대학교 산학협력단 미립화된 수용액 방울의 증발냉각을 이용한 미소유체 냉각장치
JP2017078664A (ja) * 2015-10-21 2017-04-27 東洋製罐グループホールディングス株式会社 免疫学的測定デバイス
WO2017079507A1 (en) 2015-11-06 2017-05-11 Regents Of The University Of Michigan Droplet-based microfluidic rheometer system
EP3384275A2 (en) 2015-12-02 2018-10-10 Maastricht University Method for determining haemostasis under shear
US11112400B2 (en) 2016-01-16 2021-09-07 Hewlett-Packard Development Company, L.P. Blood characteristic measurement
CN105842432B (zh) * 2016-04-29 2019-01-22 诺泰科生物科技（苏州）有限公司 一种血栓弹力仪
CA3029905C (en) 2016-07-12 2021-11-30 EMULATE, Inc. Uses of microfluidic devices comprising additive channels
EP3582893B1 (en) 2017-04-20 2021-03-31 Hewlett-Packard Development Company, L.P. Microfluidic reaction system
WO2018194648A1 (en) 2017-04-21 2018-10-25 Hewlett-Packard Development Company Coplanar microfluidic manipulation
US11364496B2 (en) 2017-04-21 2022-06-21 Hewlett-Packard Development Company, L.P. Coplanar fluidic interconnect
EP3582894A4 (en) 2017-04-21 2020-03-04 Hewlett-Packard Development Company, L.P. MICROFLUIDIC CHIP
JP7021253B2 (ja) * 2017-04-21 2022-02-16 ヒューレット－パッカード デベロップメント カンパニー エル．ピー． チップ対チップの流体相互接続
JP6339274B1 (ja) * 2017-06-19 2018-06-06 積水化学工業株式会社 マイクロ流体デバイス
JP7214712B2 (ja) * 2017-07-28 2023-01-30 マサチューセッツ インスティテュート オブ テクノロジー 血漿および全血中の抗凝固薬の検出のための方法ならびにデバイス
CN114414790A (zh) * 2017-11-28 2022-04-29 北京碧澄生物科技有限公司 检测液体相变的装置和方法
CN108855256B (zh) * 2018-04-25 2020-06-02 南开大学 一种检测红细胞变形性的微流控芯片及其方法
WO2020068628A1 (en) 2018-09-27 2020-04-02 Siemens Healthcare Diagnostics Inc. Multi-channel device for calculating coagulation characteristics of a patient's liquid test sample and methods of use related thereto
US11389799B2 (en) 2019-01-17 2022-07-19 The Regents Of The University Of Michigan Microfluidic device for size and deformability measurements and applications thereof
BR102019004230A2 (pt) * 2019-02-28 2020-09-08 Univ Do Vale Do Rio Dos Sinos Unisinos dispositivo analítico, processo de obtenção e uso do mesmo
CN110057890B (zh) * 2019-03-26 2021-07-30 中国科学院苏州生物医学工程技术研究所 一种凝血检测芯片和电化学传感器
KR102372875B1 (ko) * 2019-05-10 2022-03-10 포항공과대학교 산학협력단 폴리이미드계 필름 기반 합성-모듈, 이의 제조방법 및 이를 이용한 유기포스페이트계 화합물의 대량 생산방법
US11465143B2 (en) * 2019-06-07 2022-10-11 Nippon Sheet Glass Company, Limited Reaction processing vessel
KR102229025B1 (ko) * 2019-07-19 2021-03-17 전북대학교산학협력단 소형 혈액점도측정 키트 및 그 카트리지
USD993443S1 (en) * 2020-02-04 2023-07-25 Ut-Battelle, Llc Microfluidic glass chip interface bracket
USD989342S1 (en) * 2020-02-04 2023-06-13 Ut-Battelle, Llc Microfluidic polymer chip interface bracket
KR20210118295A (ko) * 2020-03-20 2021-09-30 주식회사 제우스 이중관구조 플로우셀 장치
CN116547538A (zh) * 2020-11-27 2023-08-04 藤森工业株式会社 凝血检测用微芯片的制造方法
EP4112736A1 (en) * 2021-07-02 2023-01-04 Vital Signs Solutions Limited Device for testing blood plasma
CN113702649B (zh) * 2021-08-25 2022-09-02 常州工程职业技术学院 一种用于测定血液凝结时间的微流体生物芯片

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110727A (en) 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
DK15788D0 (da) * 1988-01-14 1988-01-14 Nordisk Gentofte Fremgangsmaade og apparat til maaling af fuldblods koagulation
JPH0726965B2 (ja) 1988-01-14 1995-03-29 ノボ‐ノルディスク アクティーゼルスカブ 血液試料の凝固時間の測定装置
US5039617A (en) 1989-04-20 1991-08-13 Biotrack, Inc. Capillary flow device and method for measuring activated partial thromboplastin time
JPH03189194A (ja) 1989-12-20 1991-08-19 Dainippon Printing Co Ltd 熱転写シート
US5154082A (en) 1991-05-20 1992-10-13 International Technidyne Corporation Microprocessor-controlled apparatus and method for detecting the coagulation of blood
AU663343B2 (en) 1991-10-04 1995-10-05 Dade Behring Inc. Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids
US5447440A (en) 1993-10-28 1995-09-05 I-Stat Corporation Apparatus for assaying viscosity changes in fluid samples and method of conducting same
ES2160708T3 (es) 1994-04-28 2001-11-16 Dade Behring Inc Calibrador para ensayos de tiempo de protrombina (tp).
US5418141A (en) 1994-05-06 1995-05-23 Avocet Medical, Inc. Test articles for performing dry reagent prothrombin time assays
US5504011A (en) 1994-10-21 1996-04-02 International Technidyne Corporation Portable test apparatus and associated method of performing a blood coagulation test
WO1998052691A1 (en) * 1997-05-16 1998-11-26 Alberta Research Council Microfluidic system and methods of use
AU754536B2 (en) * 1998-03-19 2002-11-21 Orgenics Biosensors Ltd. Device for the determination of blood clotting by capacitance or resistance
FR2779827B1 (fr) * 1998-06-10 2000-08-11 Junior Instruments Appareil d'analyse automatique utilisable pour la determination du temps de coagulation du sang
US6830934B1 (en) * 1999-06-15 2004-12-14 Lifescan, Inc. Microdroplet dispensing for a medical diagnostic device
WO2000006761A1 (en) 1998-07-29 2000-02-10 Hemosense, Inc. Method and device for measuring blood coagulation or lysis by viscosity changes
CN1309770A (zh) * 1998-07-31 2001-08-22 华莱士·E·卡罗尔 确定抗凝治疗因子的设备和方法
FI106366B (fi) 1999-02-17 2001-01-31 Tamfelt Oyj Abp Suodatinkangas
US6733985B1 (en) 1999-05-19 2004-05-11 International Technidyne Corporation Preparation of stable liquid and dried synthetic prothrombin time reagents
CA2382143C (en) 1999-09-03 2005-10-18 Roche Diagnostics Corporation Method, reagent and test cartridge for determining clotting time
US6750053B1 (en) 1999-11-15 2004-06-15 I-Stat Corporation Apparatus and method for assaying coagulation in fluid samples
US6908593B1 (en) * 2000-03-31 2005-06-21 Lifescan, Inc. Capillary flow control in a fluidic diagnostic device
US6620310B1 (en) 2000-12-13 2003-09-16 Lifescan, Inc. Electrochemical coagulation assay and device
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
JP2003004752A (ja) * 2001-06-15 2003-01-08 Minolta Co Ltd マイクロチップおよび該マイクロチップを用いる検査装置
US6844149B2 (en) * 2001-06-29 2005-01-18 International Business Machines Corporation Method, system, and apparatus for measurement and recording of blood chemistry and other physiological measurements
WO2003079149A2 (en) * 2002-03-11 2003-09-25 The University Of Vermont And State Agriculture College Blood clotting predictor
US7901939B2 (en) * 2002-05-09 2011-03-08 University Of Chicago Method for performing crystallization and reactions in pressure-driven fluid plugs
WO2004044560A1 (en) * 2002-11-12 2004-05-27 Inverness Medical Switzerland Gmbh Photometric determination of coagulation time in undiluted whole blood
US7291310B2 (en) 2002-12-17 2007-11-06 The Regents Of The University Of Michigan Microsystem for determining clotting time of blood and low-cost, single-use device for use therein
US7419638B2 (en) * 2003-01-14 2008-09-02 Micronics, Inc. Microfluidic devices for fluid manipulation and analysis
US7854897B2 (en) * 2003-05-12 2010-12-21 Yokogawa Electric Corporation Chemical reaction cartridge, its fabrication method, and a chemical reaction cartridge drive system
US7235377B2 (en) 2003-06-09 2007-06-26 The University Of Vermont And State Agriculture College Global test of the hemostatic system
US7148067B2 (en) 2004-08-31 2006-12-12 The Board Of Trustees Of The University Of Illinois Thromboplastin reagents
CA2615278A1 (en) * 2005-08-31 2007-03-08 Egomedical Technologies Ag Coagulation test system
AU2006305163B2 (en) 2005-10-18 2012-09-27 Fujimori Kogyo Co., Ltd. Apparatus for monitoring thrombus formation and method of monitoring thrombus formation
US20070122849A1 (en) 2005-11-29 2007-05-31 Peekhaus Norbert T Rhesus monkey P2X7 purinergic receptor and uses thereof
FR2896589B1 (fr) * 2006-01-25 2008-04-25 Biocode Hycel France Sa Sa Cuvette d'analyse polyvalente
JP2007222072A (ja) * 2006-02-23 2007-09-06 Tokyo Metropolitan Univ 化学物質の並行微量分析法
WO2007099736A1 (ja) * 2006-03-03 2007-09-07 Konica Minolta Medical & Graphic, Inc. マイクロ検査チップ、光学的検出装置およびマイクロ総合分析システム
US7674616B2 (en) 2006-09-14 2010-03-09 Hemosense, Inc. Device and method for measuring properties of a sample
EP2101917A1 (en) * 2007-01-10 2009-09-23 Scandinavian Micro Biodevices A/S A microfluidic device and a microfluidic system and a method of performing a test
JP4829828B2 (ja) 2007-03-28 2011-12-07 シスメックス株式会社 血液凝固測定用試薬及び組織因子安定化方法
EP2040073A1 (en) 2007-09-20 2009-03-25 Iline Microsystems, S.L. Microfluidic device and method for fluid clotting time determination
DE102007062323A1 (de) 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Langzeitstabiles Thromboplastin-Reagenz
JP2009162650A (ja) * 2008-01-08 2009-07-23 Sony Corp 光学的測定装置
EP2313767B1 (en) * 2008-07-16 2014-02-26 International Technidyne Corporation Cuvette-based apparatus for blood coagulation measurement and testing

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