MX2009013093A - Metodos y aparatos para medir coagulacion de la sangre. - Google Patents

Metodos y aparatos para medir coagulacion de la sangre.

Info

Publication number
MX2009013093A
MX2009013093A MX2009013093A MX2009013093A MX2009013093A MX 2009013093 A MX2009013093 A MX 2009013093A MX 2009013093 A MX2009013093 A MX 2009013093A MX 2009013093 A MX2009013093 A MX 2009013093A MX 2009013093 A MX2009013093 A MX 2009013093A
Authority
MX
Mexico
Prior art keywords
reaction chambers
sample
blood
clotting
time
Prior art date
Application number
MX2009013093A
Other languages
English (en)
Inventor
Emmanuel C Mpock
Wilma Mangan
Original Assignee
Mec Dynamics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mec Dynamics Corp filed Critical Mec Dynamics Corp
Publication of MX2009013093A publication Critical patent/MX2009013093A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención proporciona aparatos y métodos para realizar ensayos para determinar el tiempo requerido para que coagule una muestra de sangre. El aparato comprende cámaras de reacción revestidas con uno o más agentes de coagulación Una gota de sangre o equivalente se coloca en la compuerta para aplicación de la muestra, se diluye y se pone' en contacto con los agentes de coagulación en las cámaras de reacción La muestra de sangre diluida puede moverse en ambos sentidos a través de las cámaras de reacción hasta que coagule la sangre El proceso de coagulación de la sangre forma estancamientos de fibrina que evitan el flujo de la muestra de sangre en las cámaras de reacción El tiempo de coagulación es el tiempo total desde que la muestra entra a las cámaras de reacción al tiempo en el cual cambia la forma de onda en las cámaras de reacción, o el movimiento o flujo de la muestra cesa, y puede medirse por turbidez.
MX2009013093A 2007-06-20 2008-06-20 Metodos y aparatos para medir coagulacion de la sangre. MX2009013093A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94529007P 2007-06-20 2007-06-20
PCT/US2008/067750 WO2008157795A1 (en) 2007-06-20 2008-06-20 Methods and apparatus for measuring blood coagulation

Publications (1)

Publication Number Publication Date
MX2009013093A true MX2009013093A (es) 2010-05-17

Family

ID=40136883

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013093A MX2009013093A (es) 2007-06-20 2008-06-20 Metodos y aparatos para medir coagulacion de la sangre.

Country Status (10)

Country Link
US (2) US20080318260A1 (es)
EP (1) EP2156172B1 (es)
JP (1) JP2010530979A (es)
CN (1) CN101720432A (es)
AU (1) AU2008265604A1 (es)
BR (1) BRPI0812391A2 (es)
CA (1) CA2689170A1 (es)
MX (1) MX2009013093A (es)
RU (1) RU2010101672A (es)
WO (1) WO2008157795A1 (es)

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JP6052267B2 (ja) * 2009-01-08 2016-12-27 ソニー株式会社 血液凝固系解析装置、血液凝固系解析方法及びプログラム
WO2010122158A1 (en) * 2009-04-23 2010-10-28 Dublin City University A lateral flow assay device for coagulation monitoring and method thereof
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Also Published As

Publication number Publication date
EP2156172A4 (en) 2010-06-09
CN101720432A (zh) 2010-06-02
US20120142114A1 (en) 2012-06-07
US20080318260A1 (en) 2008-12-25
CA2689170A1 (en) 2008-12-24
WO2008157795A1 (en) 2008-12-24
BRPI0812391A2 (pt) 2015-11-24
RU2010101672A (ru) 2011-07-27
EP2156172B1 (en) 2013-02-20
AU2008265604A1 (en) 2008-12-24
JP2010530979A (ja) 2010-09-16
EP2156172A1 (en) 2010-02-24

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