DE602007011661D1 - Verfahren zur messung der konzentration transienter proteolytischer aktivität in zellen enthaltenden zusammengesetzten biologischen medien - Google Patents

Verfahren zur messung der konzentration transienter proteolytischer aktivität in zellen enthaltenden zusammengesetzten biologischen medien

Info

Publication number
DE602007011661D1
DE602007011661D1 DE602007011661T DE602007011661T DE602007011661D1 DE 602007011661 D1 DE602007011661 D1 DE 602007011661D1 DE 602007011661 T DE602007011661 T DE 602007011661T DE 602007011661 T DE602007011661 T DE 602007011661T DE 602007011661 D1 DE602007011661 D1 DE 602007011661D1
Authority
DE
Germany
Prior art keywords
transienter
concentration
measuring
cells containing
proteolytic activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007011661T
Other languages
English (en)
Inventor
Peter L A Giesen
Kerry Tappenden
Wynne Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thrombinoscope BV
Original Assignee
Thrombinoscope BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thrombinoscope BV filed Critical Thrombinoscope BV
Publication of DE602007011661D1 publication Critical patent/DE602007011661D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602007011661T 2006-11-02 2007-11-02 Verfahren zur messung der konzentration transienter proteolytischer aktivität in zellen enthaltenden zusammengesetzten biologischen medien Active DE602007011661D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06022813 2006-11-02
PCT/EP2007/009528 WO2008052795A1 (en) 2006-11-02 2007-11-02 Method for measuring the concentration of transient proteolytic activity in composite biological media containing cells

Publications (1)

Publication Number Publication Date
DE602007011661D1 true DE602007011661D1 (de) 2011-02-10

Family

ID=37763889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007011661T Active DE602007011661D1 (de) 2006-11-02 2007-11-02 Verfahren zur messung der konzentration transienter proteolytischer aktivität in zellen enthaltenden zusammengesetzten biologischen medien

Country Status (10)

Country Link
US (1) US8343730B2 (de)
EP (1) EP2087131B1 (de)
JP (1) JP2010508036A (de)
KR (1) KR20090085666A (de)
CN (1) CN101548019A (de)
AT (1) ATE493505T1 (de)
AU (1) AU2007315210A1 (de)
CA (1) CA2668356A1 (de)
DE (1) DE602007011661D1 (de)
WO (1) WO2008052795A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5461175B2 (ja) * 2006-06-06 2014-04-02 トロームビノスコープ ベスローテン フェンノートシャップ 生体媒質中で酵素活性を決定する方法
CA2668356A1 (en) 2006-11-02 2008-05-08 Thrombinoscope B.V. Method for measuring the concentration of transient proteolytic activity in composite biological media containing cells
ATE516504T1 (de) * 2008-02-07 2011-07-15 Synapse Bv Um den einfluss von störfaktoren korrigierte messung des zeitlichen verlaufs einer enzymatischen aktivität bei der reaktion eines enzyms mit einem substrat
JP5385686B2 (ja) * 2009-06-05 2014-01-08 サントリーホールディングス株式会社 血小板凝集抑制剤
US8293493B2 (en) * 2010-01-27 2012-10-23 Adventist Health System/Sunbelt, Inc. Thrombin generation determination method
WO2015013495A1 (en) * 2013-07-26 2015-01-29 The University Of North Carolina At Chapel Hill Methods and compositions for detecting coagulation inhibitors
CN104965017B (zh) * 2015-06-17 2017-06-16 广西师范学院 水蛭素抗凝血酶活性的测定方法
WO2017130528A1 (ja) * 2016-01-29 2017-08-03 ソニー株式会社 血液凝固系解析装置、血液凝固系解析システム、血液凝固系解析方法及び血液凝固系解析装置用パラメーターの決定方法
EP4269605A1 (de) * 2020-12-28 2023-11-01 Fujimori Kogyo Co., Ltd. Blutgerinnungsinspektionsverfahren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1159448B1 (de) 1999-03-04 2004-04-14 Synapse B.V. Bestimmung von biologisch aktiven formen von proteolytischen enzymen
US6740096B2 (en) 2002-01-16 2004-05-25 Scimed Life Systems, Inc. Treatment and removal of objects in anatomical lumens
CN100350252C (zh) * 2002-05-01 2007-11-21 瑟纳普斯有限责任公司 实时测定凝血酶活性的方法及实施该方法的试剂盒
EP1717588A1 (de) * 2005-04-29 2006-11-02 Synapse B.V. Bestimmung der Thrombinaktivität in Vollblut
JP5461175B2 (ja) 2006-06-06 2014-04-02 トロームビノスコープ ベスローテン フェンノートシャップ 生体媒質中で酵素活性を決定する方法
CA2668356A1 (en) 2006-11-02 2008-05-08 Thrombinoscope B.V. Method for measuring the concentration of transient proteolytic activity in composite biological media containing cells

Also Published As

Publication number Publication date
EP2087131A1 (de) 2009-08-12
CN101548019A (zh) 2009-09-30
EP2087131B1 (de) 2010-12-29
US8343730B2 (en) 2013-01-01
CA2668356A1 (en) 2008-05-08
AU2007315210A1 (en) 2008-05-08
JP2010508036A (ja) 2010-03-18
US20100105091A1 (en) 2010-04-29
WO2008052795A1 (en) 2008-05-08
KR20090085666A (ko) 2009-08-07
ATE493505T1 (de) 2011-01-15

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