ATE516504T1 - Um den einfluss von störfaktoren korrigierte messung des zeitlichen verlaufs einer enzymatischen aktivität bei der reaktion eines enzyms mit einem substrat - Google Patents
Um den einfluss von störfaktoren korrigierte messung des zeitlichen verlaufs einer enzymatischen aktivität bei der reaktion eines enzyms mit einem substratInfo
- Publication number
- ATE516504T1 ATE516504T1 AT08151181T AT08151181T ATE516504T1 AT E516504 T1 ATE516504 T1 AT E516504T1 AT 08151181 T AT08151181 T AT 08151181T AT 08151181 T AT08151181 T AT 08151181T AT E516504 T1 ATE516504 T1 AT E516504T1
- Authority
- AT
- Austria
- Prior art keywords
- enzyme
- substrate
- signal
- activity
- measurement
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/974—Thrombin
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08151181A EP2088435B1 (de) | 2008-02-07 | 2008-02-07 | Um den Einfluss von Störfaktoren korrigierte Messung des zeitlichen Verlaufs einer enzymatischen Aktivität bei der Reaktion eines Enzyms mit einem Substrat |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE516504T1 true ATE516504T1 (de) | 2011-07-15 |
Family
ID=39203204
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08151181T ATE516504T1 (de) | 2008-02-07 | 2008-02-07 | Um den einfluss von störfaktoren korrigierte messung des zeitlichen verlaufs einer enzymatischen aktivität bei der reaktion eines enzyms mit einem substrat |
Country Status (4)
Country | Link |
---|---|
US (1) | US8551722B2 (de) |
EP (1) | EP2088435B1 (de) |
AT (1) | ATE516504T1 (de) |
WO (1) | WO2009098313A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8293493B2 (en) * | 2010-01-27 | 2012-10-23 | Adventist Health System/Sunbelt, Inc. | Thrombin generation determination method |
RU2518247C2 (ru) * | 2011-07-26 | 2014-06-10 | Общество с ограниченной ответственностью "ГемаКор Лабс" (ООО "ГемаКор Лабс") | Способ определения пространственно-временного распределения активности протеолитического фермента в гетерогенной системе, устройство для реализации указанного способа и способ диагностики нарушений системы гемостаза по изменению пространственно-временного распределения активности протеолитического фермента в гетерогенной системе |
EP2677037B1 (de) | 2012-06-21 | 2016-04-13 | Synapse B.V. | Gleichzeitige Messung der Thrombinerzeugung und Gerinnselfestigkeit in Plasma und im gesamten Blut |
JP7009998B2 (ja) | 2016-01-29 | 2022-01-26 | ソニーグループ株式会社 | 血液凝固系解析装置、血液凝固系解析システム、血液凝固系解析方法及び血液凝固系解析装置用パラメーターの決定方法 |
EP3363912B1 (de) | 2017-02-17 | 2020-10-28 | Synapse B.V. | Selbstkalibrierter assay zur bestimmung der erzeugung von proteolytischem enzym, dedizierte mittel und verwendungen davon |
CN116793976B (zh) * | 2023-06-29 | 2024-05-10 | 徐詹程 | 一种酶促反应分析底物浓度拟合标准曲线的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4287180A (en) * | 1980-01-28 | 1981-09-01 | Baxter Travenol Laboratories, Inc. | Method for treating blood clotting factor inhibitors |
DE69530043T2 (de) | 1994-11-08 | 2003-10-16 | Tosoh Corp., Shinnanyo | Verfahren zur Bestimmung einer fluoreszierenden Substanz, sowie Verfahren zur Enzym-Aktivität-Bestimmung |
US8802386B2 (en) * | 2002-05-01 | 2014-08-12 | Synapse B.V. | Diagnostic test for determining the concentration of transient proteolytic activity in composite biological media |
EP1717588A1 (de) | 2005-04-29 | 2006-11-02 | Synapse B.V. | Bestimmung der Thrombinaktivität in Vollblut |
AU2007256357A1 (en) | 2006-06-06 | 2007-12-13 | Thrombinoscope B.V. | Method of determining enzymatic activity in biological media |
JP2010508036A (ja) * | 2006-11-02 | 2010-03-18 | トロームビノスコープ ベスローテン フェンノートシャップ | 細胞を含む複合性の生物学的媒体において一過性のプロテイン分解活性の濃度を測定するための方法 |
-
2008
- 2008-02-07 EP EP08151181A patent/EP2088435B1/de not_active Not-in-force
- 2008-02-07 AT AT08151181T patent/ATE516504T1/de not_active IP Right Cessation
-
2009
- 2009-02-06 WO PCT/EP2009/051413 patent/WO2009098313A1/en active Application Filing
- 2009-02-06 US US12/866,777 patent/US8551722B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP2088435A1 (de) | 2009-08-12 |
EP2088435B1 (de) | 2011-07-13 |
WO2009098313A1 (en) | 2009-08-13 |
US20110045512A1 (en) | 2011-02-24 |
US8551722B2 (en) | 2013-10-08 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |