HK1178526A1 - Tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof 8--7- - Google Patents

Tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof 8--7-

Info

Publication number
HK1178526A1
HK1178526A1 HK13105408.0A HK13105408A HK1178526A1 HK 1178526 A1 HK1178526 A1 HK 1178526A1 HK 13105408 A HK13105408 A HK 13105408A HK 1178526 A1 HK1178526 A1 HK 1178526A1
Authority
HK
Hong Kong
Prior art keywords
hydroxyquinoline
tertiary
carboxamide derivatives
carboxamide
derivatives
Prior art date
Application number
HK13105408.0A
Other languages
English (en)
Chinese (zh)
Inventor
Stefania Gagliardi
Sordo Simone Del
Federico Mailland
Michela Legora
Original Assignee
Polichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42026678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1178526(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem Sa filed Critical Polichem Sa
Publication of HK1178526A1 publication Critical patent/HK1178526A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/113Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK13105408.0A 2009-12-29 2013-05-06 Tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof 8--7- HK1178526A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09180902A EP2345643A1 (en) 2009-12-29 2009-12-29 New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof
PCT/EP2010/070790 WO2011080264A1 (en) 2009-12-29 2010-12-28 New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof

Publications (1)

Publication Number Publication Date
HK1178526A1 true HK1178526A1 (en) 2013-09-13

Family

ID=42026678

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13105408.0A HK1178526A1 (en) 2009-12-29 2013-05-06 Tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof 8--7-

Country Status (37)

Country Link
US (1) US8729098B2 (es)
EP (2) EP2345643A1 (es)
JP (1) JP5808754B2 (es)
KR (1) KR101666505B1 (es)
CN (2) CN102686566A (es)
AU (1) AU2010338267B2 (es)
BR (1) BR112012015728A2 (es)
CA (1) CA2783213C (es)
CL (1) CL2012001757A1 (es)
CY (1) CY1116493T1 (es)
DK (1) DK2519505T3 (es)
DO (1) DOP2012000186A (es)
EA (1) EA025563B1 (es)
EC (1) ECSP12012007A (es)
ES (1) ES2540327T3 (es)
GE (1) GEP20156244B (es)
GT (1) GT201200216A (es)
HK (1) HK1178526A1 (es)
HR (1) HRP20150749T1 (es)
HU (1) HUE027220T2 (es)
IL (1) IL220427A (es)
MA (1) MA33829B1 (es)
MX (1) MX2012007748A (es)
MY (1) MY161869A (es)
NI (1) NI201200114A (es)
NZ (1) NZ600788A (es)
PE (1) PE20130179A1 (es)
PL (1) PL2519505T3 (es)
PT (1) PT2519505E (es)
RS (1) RS54096B1 (es)
SG (1) SG181586A1 (es)
SI (1) SI2519505T1 (es)
SM (1) SMT201500182B (es)
TN (1) TN2012000320A1 (es)
UA (1) UA107949C2 (es)
WO (1) WO2011080264A1 (es)
ZA (1) ZA201204347B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2345641A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. New secondary 8-hydroxyquinoline-7-carboxamide derivatives
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents
EP2817291A1 (en) * 2012-02-24 2014-12-31 F. Hoffmann-La Roche AG Antiviral compounds
US9751838B2 (en) 2012-10-02 2017-09-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Tetrahydroquinoline derivatives and their use as Epac inhibitors
US8697753B1 (en) 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis
USD976093S1 (en) 2020-09-22 2023-01-24 Milwaukee Electric Tool Corporation Staple collation
CN220302508U (zh) 2020-09-22 2024-01-05 米沃奇电动工具公司 动力式紧固件驱动器及钉排

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US326328A (en) 1885-09-15 Broiler
US326330A (en) 1885-09-15 Harness-support
DE540842C (de) 1930-08-06 1931-12-28 Chinosol Fabrik Akt Ges Verfahren zur Darstellung der 8-Acetyloxychinolin-7-carbonsaeure
BR9604823A (pt) 1995-04-08 1999-01-05 Basf Ag Processo para controlar funggs nocivos e pragas fúngicas mistura sinérgica adequada para controlar pragas fúngicas e uso de compostos
WO1997017973A1 (en) * 1995-11-13 1997-05-22 Smithkline Beecham Corporation Hemoregulatory compounds
US6310211B1 (en) 1996-09-10 2001-10-30 Pharmacia & Upjohn Company 8-hydroxy-7-substituted quinolines as anti-viral agents
BR9815377A (pt) * 1997-09-30 2001-01-16 Daiichi Pharmaceutical Co Ltda Derivados de sulfonil
JP2001294572A (ja) * 2000-02-09 2001-10-23 Dai Ichi Seiyaku Co Ltd 新規スルホニル誘導体
AU1152702A (en) 2000-10-12 2002-04-22 Merck & Co Inc Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
US6919351B2 (en) 2000-10-12 2005-07-19 Merck & Co., Inc. Aza-and polyaza-naphthalenyl-carboxamides useful as HIV integrase inhibitors
ATE411292T1 (de) 2001-03-01 2008-10-15 Shionogi & Co Stickstoffhaltige heteroarylverbindungen mit hiv- integrase inhibierender wirkung
US7358249B2 (en) 2002-08-13 2008-04-15 Shionogi & Co., Ltd. Heterocyclic compounds having inhibitory activity against HIV integrase
WO2005033079A1 (ja) * 2003-09-30 2005-04-14 Eisai Co., Ltd. ヘテロ環化合物を含有する新規な抗真菌剤
FR2889192A1 (fr) * 2005-07-27 2007-02-02 Cytomics Systems Sa Composes antifongiques, compositions contenant ces composes et leurs utilisations
AU2007276804A1 (en) * 2006-07-26 2008-01-31 Novartis Ag Inhibitors of undecaprenyl pyrophosphate synthase
WO2009140215A2 (en) * 2008-05-11 2009-11-19 Geraghty, Erin Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds
JP5114610B1 (ja) * 2009-11-10 2013-01-09 ファイザー・インク N1−ピラゾロスピロケトンアセチル−CoAカルボキシラーゼ阻害薬
AR079529A1 (es) * 2009-12-18 2012-02-01 Incyte Corp Derivados arilo y heteroarilo sustituidos y fundidos como inhibidores de la pi3k
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents
EP2345641A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. New secondary 8-hydroxyquinoline-7-carboxamide derivatives

Also Published As

Publication number Publication date
AU2010338267A2 (en) 2012-07-26
KR20120101563A (ko) 2012-09-13
IL220427A (en) 2015-04-30
NZ600788A (en) 2013-08-30
JP5808754B2 (ja) 2015-11-10
NI201200114A (es) 2013-04-22
DOP2012000186A (es) 2013-01-15
ZA201204347B (en) 2013-09-25
EA025563B1 (ru) 2017-01-30
SG181586A1 (en) 2012-07-30
RS54096B1 (en) 2015-10-30
CN105384685A (zh) 2016-03-09
TN2012000320A1 (en) 2013-12-12
GEP20156244B (en) 2015-02-10
ECSP12012007A (es) 2012-08-31
BR112012015728A2 (pt) 2019-09-24
JP2013515755A (ja) 2013-05-09
DK2519505T3 (en) 2015-06-29
US8729098B2 (en) 2014-05-20
US20120309751A1 (en) 2012-12-06
MX2012007748A (es) 2012-08-03
AU2010338267A1 (en) 2012-07-19
CY1116493T1 (el) 2017-03-15
MA33829B1 (fr) 2012-12-03
AU2010338267B2 (en) 2014-03-27
HUE027220T2 (hu) 2016-10-28
SMT201500182B (it) 2015-09-07
PL2519505T3 (pl) 2015-11-30
MY161869A (en) 2017-05-15
EA201270670A1 (ru) 2013-03-29
CN102686566A (zh) 2012-09-19
ES2540327T3 (es) 2015-07-09
HRP20150749T1 (hr) 2015-08-14
EP2345643A1 (en) 2011-07-20
SI2519505T1 (sl) 2015-08-31
UA107949C2 (en) 2015-03-10
GT201200216A (es) 2014-12-26
EP2519505A1 (en) 2012-11-07
WO2011080264A1 (en) 2011-07-07
CA2783213A1 (en) 2011-07-07
KR101666505B1 (ko) 2016-10-14
EP2519505B1 (en) 2015-05-27
PE20130179A1 (es) 2013-02-24
CA2783213C (en) 2017-09-12
CL2012001757A1 (es) 2013-03-22
PT2519505E (pt) 2015-09-03

Similar Documents

Publication Publication Date Title
HRP20181493T1 (hr) Konjugati epsilon-polilizin i njihova primjena
ZA201109034B (en) Aminopyrrolidinone derivatives and uses thereof
HK1168099A1 (zh) 糖苷衍生物及其用途
PL3222617T3 (pl) Związki do kierunkowania w psma i ich zastosowania
IL213974A0 (en) Isoxazole-isoxazole and isoxazole-isothiazole derivatives
IL211042A0 (en) Imidazopyridin-2-one derivatives and uses thereof
ZA201103635B (en) Azaquinolinone derivatives and uses thereof
GB0914644D0 (en) Novel agents and uses thereof
ZA201106702B (en) Sceletium extract and uses thereof
GB0921001D0 (en) Products and uses
HK1178526A1 (en) Tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof 8--7-
GB0912744D0 (en) Methods and uses
GB0909768D0 (en) Novel compounds and uses thereof
EP2408808A4 (en) TERMINAL-FUNCTIONALIZED CONJUGATES AND THEIR USE
IL206951A0 (en) 3-alkyl-piperazine derivatives and uses thereof
EP2274294A4 (en) 5-DIMETHOXY FUMAGILLOL AND ITS DERIVATIVES
GB0905525D0 (en) Compounds and uses
GB0909792D0 (en) Composition and uses thereof
GB0920904D0 (en) Uses and methods
GB0903145D0 (en) Medicaments uses and methods
GB0908087D0 (en) Novel compounds and uses thereof
IL206950A0 (en) Aminopiperidinyl derivatives and uses thereof
GB0910620D0 (en) Agents and uses thereof
AU2009903870A0 (en) Flow-Aerator and Wave-Mixer
PL387177A1 (pl) Związki enaminokarbonylowe i ich zastosowanie

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181225