HK1175781A1 - Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carbox-amides 5-(2---4-)-2--1h--3- - Google Patents
Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carbox-amides 5-(2---4-)-2--1h--3-Info
- Publication number
- HK1175781A1 HK1175781A1 HK13103041.8A HK13103041A HK1175781A1 HK 1175781 A1 HK1175781 A1 HK 1175781A1 HK 13103041 A HK13103041 A HK 13103041A HK 1175781 A1 HK1175781 A1 HK 1175781A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- carbox
- pyrimidin
- pyrrole
- amides
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09175063 | 2009-11-04 | ||
| PCT/EP2010/066241 WO2011054714A1 (en) | 2009-11-04 | 2010-10-27 | Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h-pyrrole-3-carboxamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1175781A1 true HK1175781A1 (en) | 2013-07-12 |
Family
ID=43431011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK13103041.8A HK1175781A1 (en) | 2009-11-04 | 2013-03-12 | Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1h- pyrrole-3-carbox-amides 5-(2---4-)-2--1h--3- |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8592583B2 (es) |
| EP (1) | EP2496570B1 (es) |
| JP (1) | JP5715146B2 (es) |
| CN (1) | CN102666527B (es) |
| AR (1) | AR078883A1 (es) |
| AU (1) | AU2010314204B2 (es) |
| BR (1) | BR112012010445B1 (es) |
| CA (1) | CA2779785C (es) |
| CL (1) | CL2012001140A1 (es) |
| EA (1) | EA021299B1 (es) |
| ES (1) | ES2593630T3 (es) |
| HK (1) | HK1175781A1 (es) |
| MX (1) | MX339634B (es) |
| TW (1) | TWI478914B (es) |
| WO (1) | WO2011054714A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2699564B1 (en) * | 2011-04-19 | 2016-12-14 | Nerviano Medical Sciences S.r.l. | Substituted pyrimidinyl-pyrroles active as kinase inhibitors |
| CN107915720B (zh) * | 2016-10-08 | 2020-09-11 | 常州市第四制药厂有限公司 | 沃诺拉赞的新制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09295967A (ja) * | 1996-05-02 | 1997-11-18 | Sumitomo Metal Ind Ltd | 新規ピロールアルカン酸誘導体 |
| SE0202463D0 (sv) * | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel compounds |
| JP2007519754A (ja) * | 2004-01-30 | 2007-07-19 | スミスクライン ビーチャム コーポレーション | 化合物 |
| CA2620818A1 (en) * | 2005-09-02 | 2007-03-08 | Astellas Pharma Inc. | Amide derivatives as rock inhibitors |
| TWI394749B (zh) * | 2006-03-27 | 2013-05-01 | 內維亞諾醫學公司 | 具有激酶抑制劑活性之雜戊環 |
| TWI426074B (zh) * | 2008-04-30 | 2014-02-11 | Nerviano Medical Sciences Srl | ５－（２－胺基－嘧啶－４－基）－２－芳基－１ｈ－吡咯－３－羧醯胺之製造方法 |
-
2010
- 2010-10-27 CN CN201080049620.4A patent/CN102666527B/zh active Active
- 2010-10-27 CA CA2779785A patent/CA2779785C/en active Active
- 2010-10-27 JP JP2012537345A patent/JP5715146B2/ja active Active
- 2010-10-27 AU AU2010314204A patent/AU2010314204B2/en not_active Ceased
- 2010-10-27 BR BR112012010445-4A patent/BR112012010445B1/pt active IP Right Grant
- 2010-10-27 WO PCT/EP2010/066241 patent/WO2011054714A1/en active Application Filing
- 2010-10-27 US US13/505,357 patent/US8592583B2/en active Active
- 2010-10-27 MX MX2012004844A patent/MX339634B/es active IP Right Grant
- 2010-10-27 EP EP10774186.0A patent/EP2496570B1/en active Active
- 2010-10-27 EA EA201290276A patent/EA021299B1/ru not_active IP Right Cessation
- 2010-10-27 ES ES10774186.0T patent/ES2593630T3/es active Active
- 2010-11-01 TW TW099137433A patent/TWI478914B/zh active
- 2010-11-03 AR ARP100104064A patent/AR078883A1/es active IP Right Grant
-
2012
- 2012-04-30 CL CL2012001140A patent/CL2012001140A1/es unknown
-
2013
- 2013-03-12 HK HK13103041.8A patent/HK1175781A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP5715146B2 (ja) | 2015-05-07 |
| CN102666527A (zh) | 2012-09-12 |
| JP2013510110A (ja) | 2013-03-21 |
| TW201121954A (en) | 2011-07-01 |
| MX339634B (es) | 2016-06-02 |
| CL2012001140A1 (es) | 2012-08-31 |
| CA2779785A1 (en) | 2011-05-12 |
| CN102666527B (zh) | 2014-10-01 |
| AU2010314204B2 (en) | 2015-03-26 |
| TWI478914B (zh) | 2015-04-01 |
| US8592583B2 (en) | 2013-11-26 |
| BR112012010445A2 (pt) | 2015-09-29 |
| EA021299B1 (ru) | 2015-05-29 |
| BR112012010445B1 (pt) | 2021-09-21 |
| AR078883A1 (es) | 2011-12-07 |
| EA201290276A1 (ru) | 2012-12-28 |
| EP2496570A1 (en) | 2012-09-12 |
| EP2496570B1 (en) | 2016-06-29 |
| AU2010314204A1 (en) | 2012-06-21 |
| ES2593630T3 (es) | 2016-12-12 |
| MX2012004844A (es) | 2012-06-12 |
| WO2011054714A1 (en) | 2011-05-12 |
| US20120220771A1 (en) | 2012-08-30 |
| CA2779785C (en) | 2017-09-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20231029 |