HK1174026A1 - Tricyclic antibiotics - Google Patents

Tricyclic antibiotics

Info

Publication number
HK1174026A1
HK1174026A1 HK13100956.7A HK13100956A HK1174026A1 HK 1174026 A1 HK1174026 A1 HK 1174026A1 HK 13100956 A HK13100956 A HK 13100956A HK 1174026 A1 HK1174026 A1 HK 1174026A1
Authority
HK
Hong Kong
Prior art keywords
tricyclic
antibiotics
tricyclic antibiotics
Prior art date
Application number
HK13100956.7A
Other languages
English (en)
Chinese (zh)
Inventor
Brangre Gaucher
Franck Hubert Danel
Xiaohu Tang
Tong Xie
Lin Xu
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of HK1174026A1 publication Critical patent/HK1174026A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • C07D491/147Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK13100956.7A 2009-12-18 2013-01-22 Tricyclic antibiotics HK1174026A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09179956 2009-12-18
PCT/EP2010/070043 WO2011073378A1 (en) 2009-12-18 2010-12-17 Tricyclic antibiotics

Publications (1)

Publication Number Publication Date
HK1174026A1 true HK1174026A1 (en) 2013-05-31

Family

ID=41716611

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13100956.7A HK1174026A1 (en) 2009-12-18 2013-01-22 Tricyclic antibiotics

Country Status (20)

Country Link
US (2) US8927541B2 (es)
EP (1) EP2513115B1 (es)
JP (1) JP5697685B2 (es)
KR (1) KR101891834B1 (es)
CN (1) CN102666548B (es)
AU (1) AU2010332767B2 (es)
BR (1) BR112012014519A8 (es)
CA (1) CA2780006A1 (es)
CY (1) CY1114802T1 (es)
DK (1) DK2513115T3 (es)
ES (1) ES2441348T3 (es)
HK (1) HK1174026A1 (es)
HR (1) HRP20140005T1 (es)
MX (1) MX2012006094A (es)
PL (1) PL2513115T3 (es)
PT (1) PT2513115E (es)
SI (1) SI2513115T1 (es)
TW (1) TWI487709B (es)
WO (1) WO2011073378A1 (es)
ZA (1) ZA201203540B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2721034B1 (en) * 2011-06-17 2016-07-20 Basilea Pharmaceutica AG N-heterotricyclic antibiotics
AR090880A1 (es) * 2012-04-30 2014-12-10 Janssen R & D Ireland Derivados de pirimidina
GB201406486D0 (en) 2014-04-10 2014-05-28 Redx Pharma Ltd Antibacterial compounds
WO2016105468A1 (en) * 2014-12-23 2016-06-30 Proteostasis Therapeutics, Inc. Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
CN110177796B (zh) * 2017-01-06 2022-04-08 阿斯克里斯有限公司 喹啉酮衍生物及其用于预防或治疗变应性疾病的药物组合物
AU2023235233A1 (en) 2022-03-14 2024-09-12 Slap Pharmaceuticals Llc Multicyclic compounds

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430148A (en) 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
US6939871B2 (en) 2000-10-26 2005-09-06 Smithkline Beecham P.L.C. Benzoxazinone derivatives, their preparation and use
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR042486A1 (es) 2002-12-18 2005-06-22 Glaxo Group Ltd Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion .
US7037909B2 (en) 2003-07-02 2006-05-02 Sugen, Inc. Tetracyclic compounds as c-Met inhibitors
JP2007513082A (ja) 2003-11-10 2007-05-24 シエーリング アクチエンゲゼルシャフト Ccr−5アンタゴニストとして有用なベンジルエーテルアミン化合物
GB0403038D0 (en) 2004-02-11 2004-03-17 Novartis Ag Organic compounds
EP1773831A1 (en) * 2004-07-08 2007-04-18 Glaxo Group Limited Antibacterial agents
DE102004041163A1 (de) 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
WO2006038734A1 (en) 2004-10-08 2006-04-13 Astellas Pharma Inc. Pyridazinone derivatives cytokines inhibitors
TW200615273A (en) * 2004-11-10 2006-05-16 Nicholas Piramal India Ltd Fused tricyclic compounds as inhibitors of tumor necrosis factor-alpha
JP5023054B2 (ja) 2005-03-31 2012-09-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗バクテリア剤としての二環式ピラゾール化合物
WO2007052843A1 (ja) 2005-11-04 2007-05-10 Takeda Pharmaceutical Company Limited 複素環アミド化合物およびその用途
EP1996563B1 (en) 2006-02-13 2012-03-21 F. Hoffmann-La Roche AG Heterobicyclic sulfonamide derivatives for the treatment of diabetes
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
GB0707708D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
WO2009012647A1 (fr) 2007-07-20 2009-01-29 Shanghai Hengrui Pharmaceutical Co., Ltd. Procédés de préparation de dérivés de quinazoline et leurs utilisations pharmaceutiques
WO2009125809A1 (ja) 2008-04-11 2009-10-15 第一三共株式会社 ピペリジン誘導体
WO2009125808A1 (ja) * 2008-04-11 2009-10-15 第一三共株式会社 アミノシクロヘキシル誘導体
TW200944529A (en) * 2008-04-15 2009-11-01 Actelion Pharmaceuticals Ltd Tricyclic antibiotics
DE102008028996B4 (de) 2008-06-20 2011-06-09 Technische Universität Braunschweig Verfahren zur Nachbehandlung einer Schweißverbindung
RU2011108008A (ru) 2008-08-04 2012-09-10 Актелион Фармасьютиклз Лтд (Ch) Производные трициклического алкиламинометилоксазолидинона

Also Published As

Publication number Publication date
AU2010332767A1 (en) 2012-05-24
TW201132645A (en) 2011-10-01
ZA201203540B (en) 2013-01-30
CY1114802T1 (el) 2016-12-14
TWI487709B (zh) 2015-06-11
HRP20140005T1 (hr) 2014-01-31
KR101891834B1 (ko) 2018-09-28
PL2513115T3 (pl) 2014-04-30
BR112012014519A8 (pt) 2017-12-26
WO2011073378A1 (en) 2011-06-23
BR112012014519A2 (pt) 2016-08-16
CN102666548A (zh) 2012-09-12
SI2513115T1 (sl) 2014-02-28
DK2513115T3 (da) 2014-01-13
US20120245345A1 (en) 2012-09-27
CA2780006A1 (en) 2011-06-23
US8927541B2 (en) 2015-01-06
JP5697685B2 (ja) 2015-04-08
KR20120101711A (ko) 2012-09-14
EP2513115A1 (en) 2012-10-24
EP2513115B1 (en) 2013-10-09
JP2013514331A (ja) 2013-04-25
PT2513115E (pt) 2013-12-19
AU2010332767B2 (en) 2014-04-24
ES2441348T3 (es) 2014-02-04
US9120822B2 (en) 2015-09-01
CN102666548B (zh) 2015-07-15
MX2012006094A (es) 2012-06-19
US20150072975A1 (en) 2015-03-12

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20191215