HK1173724A1 - -吡唑並螺酮乙酰輔酶 羧化酶抑制劑 - Google Patents

-吡唑並螺酮乙酰輔酶 羧化酶抑制劑

Info

Publication number
HK1173724A1
HK1173724A1 HK13100478.6A HK13100478A HK1173724A1 HK 1173724 A1 HK1173724 A1 HK 1173724A1 HK 13100478 A HK13100478 A HK 13100478A HK 1173724 A1 HK1173724 A1 HK 1173724A1
Authority
HK
Hong Kong
Prior art keywords
coa carboxylase
carboxylase inhibitors
pyrazolospiroketone
acetyl
pyrazolospiroketone acetyl
Prior art date
Application number
HK13100478.6A
Other languages
English (en)
Inventor
．巴格利
．格裡菲斯
．孔
Original Assignee
輝瑞大藥廠
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 輝瑞大藥廠 filed Critical 輝瑞大藥廠
Publication of HK1173724A1 publication Critical patent/HK1173724A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
HK13100478.6A 2009-11-10 2013-01-11 -吡唑並螺酮乙酰輔酶 羧化酶抑制劑 HK1173724A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25982309P 2009-11-10 2009-11-10
PCT/IB2010/054908 WO2011058474A1 (en) 2009-11-10 2010-10-29 N1-pyrazolospiroketone acetyl-coa carboxylase inhibitors

Publications (1)

Publication Number Publication Date
HK1173724A1 true HK1173724A1 (zh) 2013-05-24

Family

ID=43357094

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13100478.6A HK1173724A1 (zh) 2009-11-10 2013-01-11 -吡唑並螺酮乙酰輔酶 羧化酶抑制劑

Country Status (39)

Country Link
US (4) US8288405B2 (zh)
EP (3) EP2947082A1 (zh)
JP (1) JP5114610B1 (zh)
KR (2) KR101478517B1 (zh)
CN (1) CN102695708B (zh)
AP (1) AP3283A (zh)
AR (1) AR078944A1 (zh)
AU (1) AU2010317501B2 (zh)
BR (1) BR112012011072A2 (zh)
CA (1) CA2778886C (zh)
CL (1) CL2012000999A1 (zh)
CO (1) CO6541569A2 (zh)
CR (1) CR20120190A (zh)
CU (1) CU24077B1 (zh)
DK (1) DK2499139T3 (zh)
DO (1) DOP2012000128A (zh)
EA (1) EA020153B1 (zh)
EC (1) ECSP12011880A (zh)
ES (1) ES2444543T3 (zh)
GE (1) GEP20146169B (zh)
HK (1) HK1173724A1 (zh)
HN (1) HN2012000973A (zh)
HR (1) HRP20140025T1 (zh)
IL (1) IL219373A (zh)
MA (1) MA33734B1 (zh)
MX (1) MX2012005429A (zh)
NI (1) NI201200089A (zh)
NZ (1) NZ599815A (zh)
PE (1) PE20121469A1 (zh)
PL (1) PL2499139T3 (zh)
PT (1) PT2499139E (zh)
RS (1) RS53156B (zh)
SI (1) SI2499139T1 (zh)
TN (1) TN2012000192A1 (zh)
TW (1) TWI394756B (zh)
UA (1) UA102336C2 (zh)
UY (1) UY33020A (zh)
WO (1) WO2011058474A1 (zh)
ZA (1) ZA201204231B (zh)

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Also Published As

Publication number Publication date
EA020153B1 (ru) 2014-09-30
RS53156B (en) 2014-06-30
CR20120190A (es) 2012-05-24
IL219373A0 (en) 2012-06-28
KR20140034919A (ko) 2014-03-20
US9139587B2 (en) 2015-09-22
DOP2012000128A (es) 2012-08-31
EP2947082A1 (en) 2015-11-25
TWI394756B (zh) 2013-05-01
US8507681B2 (en) 2013-08-13
KR20120099460A (ko) 2012-09-10
HRP20140025T1 (hr) 2014-02-14
ZA201204231B (en) 2013-02-27
MA33734B1 (fr) 2012-11-01
ES2444543T3 (es) 2014-02-25
KR101478517B1 (ko) 2015-01-02
DK2499139T3 (da) 2014-01-27
NI201200089A (es) 2012-08-20
CU24077B1 (es) 2015-03-30
SI2499139T1 (sl) 2014-01-31
AR078944A1 (es) 2011-12-14
UY33020A (es) 2011-06-30
EP2499139B1 (en) 2013-12-11
CO6541569A2 (es) 2012-10-16
AU2010317501B2 (en) 2013-06-06
BR112012011072A2 (pt) 2017-06-20
WO2011058474A1 (en) 2011-05-19
CU20120071A7 (es) 2013-05-31
PT2499139E (pt) 2014-02-10
IL219373A (en) 2014-04-30
US20110111046A1 (en) 2011-05-12
UA102336C2 (uk) 2013-06-25
EP2676958B1 (en) 2015-07-01
EP2499139A1 (en) 2012-09-19
US20130030181A1 (en) 2013-01-31
AU2010317501A1 (en) 2012-05-17
KR101550557B1 (ko) 2015-09-04
CN102695708A (zh) 2012-09-26
MX2012005429A (es) 2012-06-19
WO2011058474A8 (en) 2012-04-26
PE20121469A1 (es) 2012-11-01
JP2013510192A (ja) 2013-03-21
TW201127838A (en) 2011-08-16
CN102695708B (zh) 2014-10-15
US8288405B2 (en) 2012-10-16
US20140288111A1 (en) 2014-09-25
US20130296319A1 (en) 2013-11-07
HN2012000973A (es) 2015-03-02
AP2012006269A0 (en) 2012-06-30
NZ599815A (en) 2013-04-26
AP3283A (en) 2015-05-31
EP2676958A1 (en) 2013-12-25
CL2012000999A1 (es) 2012-07-20
PL2499139T3 (pl) 2014-04-30
GEP20146169B (en) 2014-09-25
CA2778886C (en) 2014-01-07
ECSP12011880A (es) 2012-07-31
EA201290191A1 (ru) 2012-12-28
CA2778886A1 (en) 2011-05-19
JP5114610B1 (ja) 2013-01-09
TN2012000192A1 (fr) 2013-12-12
US8802690B2 (en) 2014-08-12

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20181031