HK1161898A1 - Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof - Google Patents

Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof

Info

Publication number
HK1161898A1
HK1161898A1 HK12102415.9A HK12102415A HK1161898A1 HK 1161898 A1 HK1161898 A1 HK 1161898A1 HK 12102415 A HK12102415 A HK 12102415A HK 1161898 A1 HK1161898 A1 HK 1161898A1
Authority
HK
Hong Kong
Prior art keywords
expression vector
animal cells
large quantity
foreign gene
protein derived
Prior art date
Application number
HK12102415.9A
Other languages
English (en)
Chinese (zh)
Inventor
Hiroshi Tahara
Yusuke Suzuki
Keiichi Yamamoto
Yuzuru Kitahara
Yasuhiko Suzuki
Original Assignee
Univ Hokkaido Nat Univ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Hokkaido Nat Univ Corp filed Critical Univ Hokkaido Nat Univ Corp
Publication of HK1161898A1 publication Critical patent/HK1161898A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HK12102415.9A 2008-12-22 2012-03-09 Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof HK1161898A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008325690 2008-12-22
PCT/JP2009/071326 WO2010074080A1 (ja) 2008-12-22 2009-12-22 動物細胞を用いて外来遺伝子由来タンパク質を大量に生産するための発現ベクター、およびその利用

Publications (1)

Publication Number Publication Date
HK1161898A1 true HK1161898A1 (en) 2012-08-10

Family

ID=42287688

Family Applications (3)

Application Number Title Priority Date Filing Date
HK12102415.9A HK1161898A1 (en) 2008-12-22 2012-03-09 Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof
HK12104176.4A HK1163739A1 (en) 2008-12-22 2012-04-27 Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof
HK15105079.6A HK1204651A1 (en) 2008-12-22 2015-05-28 Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
HK12104176.4A HK1163739A1 (en) 2008-12-22 2012-04-27 Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof
HK15105079.6A HK1204651A1 (en) 2008-12-22 2015-05-28 Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof

Country Status (12)

Country Link
US (1) US9096878B2 (xx)
EP (1) EP2385115B1 (xx)
JP (1) JP5704753B2 (xx)
KR (1) KR101655492B1 (xx)
CN (2) CN104342454A (xx)
AU (1) AU2009331326B2 (xx)
CA (1) CA2748011C (xx)
DK (1) DK2385115T3 (xx)
ES (1) ES2552325T3 (xx)
HK (3) HK1161898A1 (xx)
PT (1) PT2385115E (xx)
WO (1) WO2010074080A1 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2719108T3 (es) 2011-11-30 2019-07-08 Abbvie Biotechnology Ltd Vectores y células hospedadoras que comprenden un promotor de SV40 modificado para la expresión de proteínas
CN107338267A (zh) * 2016-05-03 2017-11-10 中国科学院深圳先进技术研究院 双顺反子表达载体及其构建方法与应用
BR112019019077A2 (pt) 2017-03-27 2020-04-22 Fuso Pharmaceutical Ind anticorpo anti-pd-l1 para detecção de pd-l1
EP3805396A4 (en) * 2018-05-24 2022-03-23 National University Corporation Hokkaido University NOVEL VECTOR AND USE OF THEM
CN111466337B (zh) * 2020-05-19 2022-04-19 山东大学齐鲁医院 一种腹主动脉瘤动物模型及其构建方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
AU572108B2 (en) 1983-01-19 1988-05-05 Genentech Inc. Human tpa production using vectors coding for dhfr protein
NZ210501A (en) 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
JP2648860B2 (ja) 1986-05-08 1997-09-03 イエダ リサーチ アンド デベロップメント コンパニー リミテッド ヒトインターフエロン−β２Ａ及びヒトインターフエロン−β２Ｂ、該インターフエロンをコードする遺伝子を含むベクター、該インターフエロンを産生するセルライン及び該インターフエロンの医薬品としての用途
ATE199023T1 (de) * 1991-03-29 2001-02-15 Genentech Inc Methoden zur selektion von rekombinanten wirtszellen welche hohe mengen von einem gewünschten protein exprimieren
DE4142077A1 (de) 1991-12-19 1993-06-24 Boehringer Mannheim Gmbh Verfahren zur expression rekombinanter antikoerper
JPH0630788A (ja) 1992-07-16 1994-02-08 Otsuka Pharmaceut Co Ltd ヒトインターロイキン−１に対する組換え抗体
US5648267A (en) 1992-11-13 1997-07-15 Idec Pharmaceuticals Corporation Impaired dominant selectable marker sequence and intronic insertion strategies for enhancement of expression of gene product and expression vector systems comprising same
JP3919830B2 (ja) 1992-11-28 2007-05-30 財団法人化学及血清療法研究所 抗ネコヘルペスウイルス−１組換え抗体および該抗体をコードする遺伝子断片
US5627033A (en) 1995-03-28 1997-05-06 Research & Diagnostics Systems, Inc. Mammalian expression vectors
JP3582965B2 (ja) 1996-08-23 2004-10-27 株式会社イムノ・ジャパン 哺乳動物細胞用発現ベクター
EP2278022A3 (en) * 1999-11-01 2011-05-18 Novartis Vaccines and Diagnostics, Inc. Expression vectors, transfection systems, and method of use thereof
AU2003258388C1 (en) * 2002-09-13 2010-03-18 The University Of Queensland Gene expression system based on codon translation efficiency
KR101149777B1 (ko) * 2002-11-29 2012-06-11 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 신규한 네오마이신 포스포트랜스퍼라제 유전자 및 고생산성 재조합 세포의 선별 방법
CN1771324A (zh) * 2003-02-03 2006-05-10 日本免疫股份有限公司 动物细胞用高表达载体
MX2007004595A (es) * 2004-11-08 2007-08-15 Chromagenics Bv Seleccion de celulas hospederas que expresan proteinas en altas concentraciones.
EP2390326B1 (en) * 2005-03-31 2014-07-09 Fuso Pharmaceutical Industries Ltd. Process of producing human type II collagen
EP1987150B1 (en) 2006-02-21 2011-06-01 ChromaGenics B.V. Selection of host cells expressing protein at high levels
CA2716766A1 (en) 2008-02-27 2009-09-03 Fuso Pharmaceutical Industries, Ltd. Expression vector for mass production of foreign gene-derived protein using animal cell and use thereof
CA2748015C (en) 2008-12-22 2017-02-28 National University Corporation Hokkaido University Protein substance having triple helix structure and manufacturing method therefor

Also Published As

Publication number Publication date
KR20110106392A (ko) 2011-09-28
CA2748011C (en) 2019-02-26
CN102325881A (zh) 2012-01-18
AU2009331326A2 (en) 2011-08-11
DK2385115T3 (en) 2015-11-30
CA2748011A1 (en) 2010-07-01
CN102325881B (zh) 2014-08-20
US20120122083A1 (en) 2012-05-17
EP2385115A4 (en) 2012-08-08
JPWO2010074080A1 (ja) 2012-06-21
AU2009331326A1 (en) 2011-07-07
AU2009331326B2 (en) 2014-09-18
HK1204651A1 (en) 2015-11-27
KR101655492B1 (ko) 2016-09-07
EP2385115B1 (en) 2015-09-09
US9096878B2 (en) 2015-08-04
JP5704753B2 (ja) 2015-04-22
PT2385115E (pt) 2015-11-24
ES2552325T3 (es) 2015-11-27
EP2385115A1 (en) 2011-11-09
CN104342454A (zh) 2015-02-11
HK1163739A1 (en) 2012-09-14
WO2010074080A1 (ja) 2010-07-01

Similar Documents

Publication Publication Date Title
HK1221266A1 (zh) 單細胞中的基因表達分析
ZA201606403B (en) Pluripotent stem cell culture on micro-carriers
AP2011005557A0 (en) Improved protein production and storage in plants.
IL202213A0 (en) Recombinant protein production in avian ebxr cells
ZA201103584B (en) Whey protein compositions,methods and uses
EP2694660A4 (en) EFFICIENT IN VIVO PROTEIN EXPRESSION USING MODIFIED RNA (MOD RNA)
PL2295039T5 (pl) Sposób wytwarzania granulek zawierających pankreatynę, w szczególności mikrogranulek zawierających pankreatynę, oraz wytworzone tym sposobem granulki zawierające pankreatynę
IL188202A0 (en) Methods and compositions for expressing negative-sense viral rna in canine cells
HK1143404A1 (en) Cell for use in the production of exogenous protein, and production process using the cell
HK1204651A1 (en) Expression vector for producing protein derived from foreign gene in large quantity using animal cells, and use thereof
HK1190306A1 (zh) 含有心源性因子的組合物和相關方法、細胞，以及所述組合物、方法和細胞的應用
GB0602992D0 (en) Methods, genes and proteins
HK1136849A1 (en) Methods and compositions for expressing negative-sense viral rna in canine cells rna
EP2218786A4 (en) ARTIFICIAL CHROMOSOMIC MAMMALIAN VECTOR CARRYING THE HUMAN CYTOCHROME P450 GENE (GENE GROUP), AND NON-HUMAN MAMMAL THAT CARRY THE VECTOR
EP2643012A4 (en) PROTEIN ADMINISTRATION FROM STEM CELL MICROVECTORS
EP2185723A4 (en) EFFECT OF A GENETIC VARIATION IN THE GENESIS OF PROMELANIN CONCENTRATING HORMONE ON THE MEAT PROPERTIES IN BOVINE ANIMALS
EP2439275A4 (en) GENE FOR INCREASING PROTEIN CONTENT IN SEEDS AND METHOD FOR ITS USE
EP2438166A4 (en) PROCESS FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL
HK1155772A1 (en) Expression vector for mass production of foreign gene-derived protein using animal cell and use thereof
EP2719764A4 (en) EXPRESSION VECTOR FOR ANIMAL CELLS USING THE FACTOR CSP-B-5'-SAR AND METHOD FOR PRODUCING RECOMBINANT PROTEINS THEREWITH
GB0820397D0 (en) Cells, nucleic acid constructs, cells comprising said constructs and methods utilizing said cells in the treatment of diseases
EP2274418A4 (en) HUMAN HOST CELL FOR PRODUCING RECOMBINANT PROTEINS WITH HIGH QUALITY AND LARGE QUANTITY
HK1154046A1 (en) Methods and compositions for production of recombinant protein in hbx- expressing mammalian cells hbx
EP2382317A4 (en) PROTEINS THAT INTERACT WITH TOR (TIP) AND THEIR GENES
EP2314701A4 (en) RECOMBINANT EXPRESSION VECTOR FOR ANIMAL CELL