HK1159064A1 - Processes for the preparation of aminosulfone compounds - Google Patents

Processes for the preparation of aminosulfone compounds

Info

Publication number
HK1159064A1
HK1159064A1 HK11112896.7A HK11112896A HK1159064A1 HK 1159064 A1 HK1159064 A1 HK 1159064A1 HK 11112896 A HK11112896 A HK 11112896A HK 1159064 A1 HK1159064 A1 HK 1159064A1
Authority
HK
Hong Kong
Prior art keywords
processes
preparation
aminosulfone compounds
aminosulfone
compounds
Prior art date
Application number
HK11112896.7A
Other languages
English (en)
Inventor
Manohar T Saindane
Chuansheng Ge
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of HK1159064A1 publication Critical patent/HK1159064A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK11112896.7A 2008-09-10 2011-11-28 Processes for the preparation of aminosulfone compounds HK1159064A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9590208P 2008-09-10 2008-09-10
PCT/US2009/005055 WO2010030345A2 (fr) 2008-09-10 2009-09-09 Procédés pour la préparation de composés d’aminosulfone

Publications (1)

Publication Number Publication Date
HK1159064A1 true HK1159064A1 (en) 2012-07-27

Family

ID=41565187

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11112896.7A HK1159064A1 (en) 2008-09-10 2011-11-28 Processes for the preparation of aminosulfone compounds

Country Status (16)

Country Link
US (1) US8242310B2 (fr)
EP (1) EP2334639B1 (fr)
JP (1) JP5513508B2 (fr)
CN (1) CN102209709B (fr)
CA (1) CA2736171A1 (fr)
DK (1) DK2334639T3 (fr)
ES (1) ES2404336T3 (fr)
HK (1) HK1159064A1 (fr)
HR (1) HRP20130356T1 (fr)
MX (1) MX2011002589A (fr)
MY (1) MY155424A (fr)
PL (1) PL2334639T3 (fr)
PT (1) PT2334639E (fr)
SI (1) SI2334639T1 (fr)
SM (1) SMT201300045B (fr)
WO (1) WO2010030345A2 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US9532977B2 (en) 2010-12-16 2017-01-03 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
WO2012083017A2 (fr) 2010-12-16 2012-06-21 Celgene Corporation Formes posologiques pour des médicaments médiocrement solubles administrés par voie orale à libération contrôlée et leurs utilisations
US9045417B2 (en) 2011-01-14 2015-06-02 Celgene Corporation Isotopologues of isoindole derivatives
WO2012149251A1 (fr) 2011-04-28 2012-11-01 Celgene Corporation Méthodes et compositions utilisant des inhibiteurs de la phosphodiestérase 4 (pde4) pour le traitement et la prise en charge de maladies auto-immunes et inflammatoires
MX356105B (es) 2011-09-14 2018-05-14 Celgene Corp Formulaciones de ácido ciclopropancarboxílico de {2-[(1s)-1-(3-etoxi-4-metoxi-fenil)-2-metansulfonil-etil]-3-oxo-2 ,3-dihidro-1h-isoindol-4-il}-amida.
AR090100A1 (es) * 2012-02-21 2014-10-22 Celgene Corp Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina
US9126906B2 (en) 2012-02-21 2015-09-08 Celgene Corporation Asymmetric synthetic processes for the preparation of aminosulfone compounds
EP2764866A1 (fr) 2013-02-07 2014-08-13 IP Gesellschaft für Management mbH Inhibiteurs de l'enzyme activant nedd8
KR20150126618A (ko) 2013-03-14 2015-11-12 셀진 코포레이션 아프레밀라스트를 사용하는 건선성 관절염의 치료
NZ628329A (en) 2013-06-17 2017-12-22 Celgene Corp Formulations of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
EP3142748B1 (fr) 2014-05-15 2019-09-11 Celgene Corporation Utilisation d'inhibiteurs de pde4 et de leurs combinaisons pour le traitement de la fibrose kystique
WO2015175956A1 (fr) 2014-05-16 2015-11-19 Celgene Corporation Compositions et procédés de traitement de maladies cardiovasculaires athérosclérotiques à l'aide de modulateurs de pde4
EP2949645A1 (fr) 2014-05-28 2015-12-02 LEK Pharmaceuticals d.d. Procédés de préparation de composés ß-aminosulfone
US10300042B2 (en) 2014-06-23 2019-05-28 Celgene Corporation Apremilast for the treatment of a liver disease or a liver function abnormality
US10092541B2 (en) 2014-08-15 2018-10-09 Celgene Corporation Methods for the treatment of diseases ameliorated by PDE4 inhibition using dosage titration of apremilast
US10377712B2 (en) 2015-05-26 2019-08-13 Lupin Limited Process for preparation of apremilast and novel polymorphs thereof
CN107922326A (zh) * 2015-06-09 2018-04-17 雷迪博士实验室有限公司 阿普斯特的制备方法及其中间体
EP3106457A1 (fr) 2015-06-15 2016-12-21 LEK Pharmaceuticals d.d. Nouvelle voie synthetique vers l'apremilast
EP3144393A1 (fr) 2015-09-18 2017-03-22 LEK Pharmaceuticals d.d. Voie synthétique vers l'apremilast
EP3356327A1 (fr) 2015-09-29 2018-08-08 Pliva Hrvatska D.O.O. Procédés de préparation d'aprémilast, et ses intermédiaires
US10682336B2 (en) 2015-10-21 2020-06-16 Amgen Inc. PDE4 modulators for treating and preventing immune reconstitution inflammatory syndrome (IRIS)
WO2017083348A1 (fr) 2015-11-11 2017-05-18 Celgene Corporation Formes pharmaceutiques orales à libération contrôlée de médicaments faiblement solubles et leurs utilisations
US10774041B2 (en) 2016-04-15 2020-09-15 Davuluri Ramamohan Rao Process for the preparation of apremilast
CN106543050B (zh) * 2016-09-28 2018-04-10 中南大学湘雅医院 一种阿普斯特中间体的合成工艺
HUE051684T2 (hu) 2017-04-04 2021-03-29 Quim Sintetica S A Racém béta-aminoszulfon vegyületek rezolválása
ES2866476T3 (es) 2017-04-04 2021-10-19 Quim Sintetica S A Compuestos de beta-aminosulfona racémicos
CN107011209A (zh) * 2017-05-11 2017-08-04 蚌埠中实化学技术有限公司 一种3‑甲氧基‑4‑乙氧基苯腈的合成新工艺
CN115572248B (zh) * 2022-11-08 2024-04-26 中山大学 一种制备β-氨基砜类化合物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8501192D0 (en) * 1985-01-17 1985-02-20 Boots Co Plc Therapeutic agents
JPH02289584A (ja) * 1989-02-17 1990-11-29 Takeda Chem Ind Ltd セファロスポリンγ―ラクトン化合物
EP0731086B1 (fr) * 1995-03-09 1999-04-28 Ciba SC Holding AG Procédé de préparation de nitriles aromatiques
JPH1087547A (ja) * 1996-09-13 1998-04-07 Nippon Soda Co Ltd 光学活性合成中間体の製造法
GB9711650D0 (en) * 1997-06-05 1997-07-30 Pfizer Ltd Compounds useful in therapy
US6020358A (en) * 1998-10-30 2000-02-01 Celgene Corporation Substituted phenethylsulfones and method of reducing TNFα levels
CA2511843C (fr) * 2002-12-30 2012-04-24 Celgene Corporation Composes 1, 3-dihydro-isoindolyle a substitution fluoroalcoxy et leurs utilisations pharmaceutiques

Also Published As

Publication number Publication date
JP5513508B2 (ja) 2014-06-04
US20100168475A1 (en) 2010-07-01
ES2404336T3 (es) 2013-05-27
EP2334639A2 (fr) 2011-06-22
CN102209709A (zh) 2011-10-05
CN102209709B (zh) 2014-08-13
CA2736171A1 (fr) 2010-03-18
SMT201300045B (it) 2013-07-09
MY155424A (en) 2015-10-15
MX2011002589A (es) 2011-04-07
PT2334639E (pt) 2013-04-26
WO2010030345A2 (fr) 2010-03-18
PL2334639T3 (pl) 2013-08-30
HRP20130356T1 (en) 2013-05-31
JP2012502097A (ja) 2012-01-26
WO2010030345A3 (fr) 2010-05-06
SI2334639T1 (sl) 2013-06-28
DK2334639T3 (da) 2013-05-06
EP2334639B1 (fr) 2013-01-23
US8242310B2 (en) 2012-08-14

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