HUE051684T2 - Racém béta-aminoszulfon vegyületek rezolválása - Google Patents

Racém béta-aminoszulfon vegyületek rezolválása

Info

Publication number
HUE051684T2
HUE051684T2 HUE18716164A HUE18716164A HUE051684T2 HU E051684 T2 HUE051684 T2 HU E051684T2 HU E18716164 A HUE18716164 A HU E18716164A HU E18716164 A HUE18716164 A HU E18716164A HU E051684 T2 HUE051684 T2 HU E051684T2
Authority
HU
Hungary
Prior art keywords
resolution
racemic beta
aminosulfone compounds
aminosulfone
compounds
Prior art date
Application number
HUE18716164A
Other languages
English (en)
Inventor
Giuseppe Barreca
Giovanni Marras
Bruno Romano
Original Assignee
Quim Sintetica S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quim Sintetica S A filed Critical Quim Sintetica S A
Publication of HUE051684T2 publication Critical patent/HUE051684T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HUE18716164A 2017-04-04 2018-03-28 Racém béta-aminoszulfon vegyületek rezolválása HUE051684T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17382175 2017-04-04

Publications (1)

Publication Number Publication Date
HUE051684T2 true HUE051684T2 (hu) 2021-03-29

Family

ID=58501429

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE18716164A HUE051684T2 (hu) 2017-04-04 2018-03-28 Racém béta-aminoszulfon vegyületek rezolválása

Country Status (7)

Country Link
US (1) US11149003B2 (hu)
EP (1) EP3606908B1 (hu)
ES (1) ES2829253T3 (hu)
HR (1) HRP20201376T1 (hu)
HU (1) HUE051684T2 (hu)
SI (1) SI3606908T1 (hu)
WO (1) WO2018184936A1 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018184936A1 (en) 2017-04-04 2018-10-11 Quimica Sintetica, S. A. Resolution of racemic beta-aminosulfone compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456595A (en) 1982-12-06 1984-06-26 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy aroly peptides
US6020358A (en) * 1998-10-30 2000-02-01 Celgene Corporation Substituted phenethylsulfones and method of reducing TNFα levels
US6962940B2 (en) * 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
JP5513508B2 (ja) 2008-09-10 2014-06-04 セルジーン コーポレイション アミノスルホン化合物を調製するためのプロセス
CN107964016B (zh) 2009-05-14 2021-10-01 天津合美医药科技有限公司 噻吩衍生物
AR090100A1 (es) 2012-02-21 2014-10-22 Celgene Corp Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina
US9126906B2 (en) 2012-02-21 2015-09-08 Celgene Corporation Asymmetric synthetic processes for the preparation of aminosulfone compounds
CN107635962A (zh) * 2015-03-19 2018-01-26 印度商西伯拉有限公司 用于制备阿普斯特的改进工艺
US10975117B2 (en) * 2015-11-13 2021-04-13 Api Corporation Method for producing lacosamide and intermediate thereof
CN105348172B (zh) * 2015-12-04 2017-11-14 新发药业有限公司 (s)‑1‑(4‑甲氧基‑3‑乙氧基)苯基‑2‑甲磺酰基乙胺的制备及阿普斯特的制备方法
WO2018184936A1 (en) 2017-04-04 2018-10-11 Quimica Sintetica, S. A. Resolution of racemic beta-aminosulfone compounds

Also Published As

Publication number Publication date
ES2829253T3 (es) 2021-05-31
EP3606908A1 (en) 2020-02-12
EP3606908B1 (en) 2020-06-17
WO2018184936A1 (en) 2018-10-11
US11149003B2 (en) 2021-10-19
US20200199072A1 (en) 2020-06-25
HRP20201376T1 (hr) 2020-12-11
SI3606908T1 (sl) 2020-10-30

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