SMT201300045B - Processi per la preparazione di composti di amminosolfone - Google Patents

Processi per la preparazione di composti di amminosolfone

Info

Publication number
SMT201300045B
SMT201300045B SM201300045T SM201300045T SMT201300045B SM T201300045 B SMT201300045 B SM T201300045B SM 201300045 T SM201300045 T SM 201300045T SM 201300045 T SM201300045 T SM 201300045T SM T201300045 B SMT201300045 B SM T201300045B
Authority
SM
San Marino
Prior art keywords
processes
preparation
aminosulfone compounds
aminosulfone
compounds
Prior art date
Application number
SM201300045T
Other languages
English (en)
Italian (it)
Inventor
Manohar T Saindane
Chuansheng Ge
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of SMT201300045B publication Critical patent/SMT201300045B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SM201300045T 2008-09-10 2013-04-19 Processi per la preparazione di composti di amminosolfone SMT201300045B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9590208P 2008-09-10 2008-09-10
PCT/US2009/005055 WO2010030345A2 (en) 2008-09-10 2009-09-09 Processes for the preparation of aminosulfone compounds

Publications (1)

Publication Number Publication Date
SMT201300045B true SMT201300045B (it) 2013-07-09

Family

ID=41565187

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201300045T SMT201300045B (it) 2008-09-10 2013-04-19 Processi per la preparazione di composti di amminosolfone

Country Status (16)

Country Link
US (1) US8242310B2 (xx)
EP (1) EP2334639B1 (xx)
JP (1) JP5513508B2 (xx)
CN (1) CN102209709B (xx)
CA (1) CA2736171A1 (xx)
DK (1) DK2334639T3 (xx)
ES (1) ES2404336T3 (xx)
HK (1) HK1159064A1 (xx)
HR (1) HRP20130356T1 (xx)
MX (1) MX2011002589A (xx)
MY (1) MY155424A (xx)
PL (1) PL2334639T3 (xx)
PT (1) PT2334639E (xx)
SI (1) SI2334639T1 (xx)
SM (1) SMT201300045B (xx)
WO (1) WO2010030345A2 (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US9532977B2 (en) 2010-12-16 2017-01-03 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
WO2012083017A2 (en) 2010-12-16 2012-06-21 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
US9045417B2 (en) 2011-01-14 2015-06-02 Celgene Corporation Isotopologues of isoindole derivatives
WO2012149251A1 (en) 2011-04-28 2012-11-01 Celgene Corporation Methods and compositions using pde4 inhibitors for the treatment and management of autoimmune and inflammatory diseases
MX356105B (es) 2011-09-14 2018-05-14 Celgene Corp Formulaciones de ácido ciclopropancarboxílico de {2-[(1s)-1-(3-etoxi-4-metoxi-fenil)-2-metansulfonil-etil]-3-oxo-2 ,3-dihidro-1h-isoindol-4-il}-amida.
AR090100A1 (es) * 2012-02-21 2014-10-22 Celgene Corp Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina
US9126906B2 (en) 2012-02-21 2015-09-08 Celgene Corporation Asymmetric synthetic processes for the preparation of aminosulfone compounds
EP2764866A1 (en) 2013-02-07 2014-08-13 IP Gesellschaft für Management mbH Inhibitors of nedd8-activating enzyme
KR20150126618A (ko) 2013-03-14 2015-11-12 셀진 코포레이션 아프레밀라스트를 사용하는 건선성 관절염의 치료
NZ628329A (en) 2013-06-17 2017-12-22 Celgene Corp Formulations of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
EP3142748B1 (en) 2014-05-15 2019-09-11 Celgene Corporation Use of pde4 inhibitors and combinations thereof for the treatment of cystic fibrosis
WO2015175956A1 (en) 2014-05-16 2015-11-19 Celgene Corporation Compositions and methods for the treatment of atherosclerotic cardiovascular diseases with pde4 modulators
EP2949645A1 (en) 2014-05-28 2015-12-02 LEK Pharmaceuticals d.d. Processes for the preparation of ß-aminosulfone compounds
US10300042B2 (en) 2014-06-23 2019-05-28 Celgene Corporation Apremilast for the treatment of a liver disease or a liver function abnormality
US10092541B2 (en) 2014-08-15 2018-10-09 Celgene Corporation Methods for the treatment of diseases ameliorated by PDE4 inhibition using dosage titration of apremilast
US10377712B2 (en) 2015-05-26 2019-08-13 Lupin Limited Process for preparation of apremilast and novel polymorphs thereof
CN107922326A (zh) * 2015-06-09 2018-04-17 雷迪博士实验室有限公司 阿普斯特的制备方法及其中间体
EP3106457A1 (en) 2015-06-15 2016-12-21 LEK Pharmaceuticals d.d. A novel synthetic pathway towards apremilast
EP3144393A1 (en) 2015-09-18 2017-03-22 LEK Pharmaceuticals d.d. A synthetic pathway towards apremilast
EP3356327A1 (en) 2015-09-29 2018-08-08 Pliva Hrvatska D.O.O. Processes for the preparation of apremilast and intermediates thereof
US10682336B2 (en) 2015-10-21 2020-06-16 Amgen Inc. PDE4 modulators for treating and preventing immune reconstitution inflammatory syndrome (IRIS)
WO2017083348A1 (en) 2015-11-11 2017-05-18 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
US10774041B2 (en) 2016-04-15 2020-09-15 Davuluri Ramamohan Rao Process for the preparation of apremilast
CN106543050B (zh) * 2016-09-28 2018-04-10 中南大学湘雅医院 一种阿普斯特中间体的合成工艺
HUE051684T2 (hu) 2017-04-04 2021-03-29 Quim Sintetica S A Racém béta-aminoszulfon vegyületek rezolválása
ES2866476T3 (es) 2017-04-04 2021-10-19 Quim Sintetica S A Compuestos de beta-aminosulfona racémicos
CN107011209A (zh) * 2017-05-11 2017-08-04 蚌埠中实化学技术有限公司 一种3‑甲氧基‑4‑乙氧基苯腈的合成新工艺
CN115572248B (zh) * 2022-11-08 2024-04-26 中山大学 一种制备β-氨基砜类化合物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8501192D0 (en) * 1985-01-17 1985-02-20 Boots Co Plc Therapeutic agents
JPH02289584A (ja) * 1989-02-17 1990-11-29 Takeda Chem Ind Ltd セファロスポリンγ―ラクトン化合物
EP0731086B1 (de) * 1995-03-09 1999-04-28 Ciba SC Holding AG Verfahren zur Herstellung aromatischer Nitrile
JPH1087547A (ja) * 1996-09-13 1998-04-07 Nippon Soda Co Ltd 光学活性合成中間体の製造法
GB9711650D0 (en) * 1997-06-05 1997-07-30 Pfizer Ltd Compounds useful in therapy
US6020358A (en) * 1998-10-30 2000-02-01 Celgene Corporation Substituted phenethylsulfones and method of reducing TNFα levels
CA2511843C (en) * 2002-12-30 2012-04-24 Celgene Corporation Fluoroalkoxy-substituted 1,3-dihydro-isoindolyl compounds and their pharmaceutical uses

Also Published As

Publication number Publication date
JP5513508B2 (ja) 2014-06-04
US20100168475A1 (en) 2010-07-01
ES2404336T3 (es) 2013-05-27
HK1159064A1 (en) 2012-07-27
EP2334639A2 (en) 2011-06-22
CN102209709A (zh) 2011-10-05
CN102209709B (zh) 2014-08-13
CA2736171A1 (en) 2010-03-18
MY155424A (en) 2015-10-15
MX2011002589A (es) 2011-04-07
PT2334639E (pt) 2013-04-26
WO2010030345A2 (en) 2010-03-18
PL2334639T3 (pl) 2013-08-30
HRP20130356T1 (xx) 2013-05-31
JP2012502097A (ja) 2012-01-26
WO2010030345A3 (en) 2010-05-06
SI2334639T1 (sl) 2013-06-28
DK2334639T3 (da) 2013-05-06
EP2334639B1 (en) 2013-01-23
US8242310B2 (en) 2012-08-14

Similar Documents

Publication Publication Date Title
SMT201300045B (it) Processi per la preparazione di composti di amminosolfone
SMT201600254B (it) Procedimento per la preparazione di idromagnesite
SMAP200900085A (it) 3-imidazolil-indoli per il trattamento di malattieproliferative
SMT201600131B (it) Procedimento per la produzione di piastrine
LT2303021T (lt) Junginiai, skirti vėžio gydymui
IT1401129B1 (it) Processo per la sintesi di composti benzotiadiazolici
IL210935A0 (en) Anti-malarial compounds
ZA201100123B (en) Bromine-facilitated synthesis of fluoro-sulfur compounds
ITMI20071261A1 (it) Procedimento per la preparazione di cinacalcet
IT1395596B1 (it) Procedimento per la preparazione di sitagliptin
IT1393062B1 (it) Procedimento per la preparazione di gemcitabina cloridrato
IT1397503B1 (it) Processo per la preparazione di olopatadina
FR2935701B1 (fr) Procede de preparation de composes fluores olefiniques
NO20080569L (no) Fremgangsmate for fremstilling av kalsiumforbindelser
ITMI20080195A1 (it) Procedimento per la preparazione di solifenacin
ITMI20061848A1 (it) Procedimento per la preparazione di composti feniltetrazolici
ITMI20081084A1 (it) Processo per la preparazione di brinzolamide
IT1391769B1 (it) Apparato per la formatura di pannellature
IT1392206B1 (it) Apparato per la produzione di spazzole o scope
IT1394292B1 (it) Procedimento per la sintesi di pregabalina
IT1394299B1 (it) Procedimento per la preparazione di sevelamer
IT1391776B1 (it) Procedimento per la preparazione di dexlansoprazolo
ITMI20080888A1 (it) Procedimento per la preparazione di zileuton
ITMI20080011A1 (it) Procedimento per la preparazione di diacereina
IT1398273B1 (it) Procedimento per la preparazione di 14-bromo daunomicina