SMT201600131B - Procedimento per la produzione di piastrine - Google Patents

Procedimento per la produzione di piastrine

Info

Publication number
SMT201600131B
SMT201600131B SM201600131T SM201600131T SMT201600131B SM T201600131 B SMT201600131 B SM T201600131B SM 201600131 T SM201600131 T SM 201600131T SM 201600131 T SM201600131 T SM 201600131T SM T201600131 B SMT201600131 B SM T201600131B
Authority
SM
San Marino
Prior art keywords
procedure
plates
production
Prior art date
Application number
SM201600131T
Other languages
English (en)
Inventor
Dominique Baruch
Elisabeth Cramer-Borde
Claire Dunois-Larde
Original Assignee
Inst Nat Sante Rech Med
Assist Publ Hopitaux De Paris
Univ Paris Descartes
Univ Versailles Saint Quentin En Yvelines L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Assist Publ Hopitaux De Paris, Univ Paris Descartes, Univ Versailles Saint Quentin En Yvelines L filed Critical Inst Nat Sante Rech Med
Publication of SMT201600131B publication Critical patent/SMT201600131B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/145—Thrombopoietin [TPO]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
SM201600131T 2008-12-04 2016-05-04 Procedimento per la produzione di piastrine SMT201600131B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08305881 2008-12-04
PCT/EP2009/066401 WO2010063823A1 (en) 2008-12-04 2009-12-04 Method for producing platelets
EP09768362.7A EP2352815B1 (en) 2008-12-04 2009-12-04 Method for producing platelets

Publications (1)

Publication Number Publication Date
SMT201600131B true SMT201600131B (it) 2016-07-01

Family

ID=40756593

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201600131T SMT201600131B (it) 2008-12-04 2016-05-04 Procedimento per la produzione di piastrine

Country Status (16)

Country Link
US (1) US9012221B2 (it)
EP (1) EP2352815B1 (it)
JP (1) JP5863459B2 (it)
CN (2) CN104087552A (it)
AU (1) AU2009324042B2 (it)
BR (1) BRPI0922710A8 (it)
CA (1) CA2745268C (it)
CY (1) CY1117452T1 (it)
DK (1) DK2352815T3 (it)
ES (1) ES2569610T3 (it)
HR (1) HRP20160404T8 (it)
HU (1) HUE027112T2 (it)
PL (1) PL2352815T3 (it)
SI (1) SI2352815T1 (it)
SM (1) SMT201600131B (it)
WO (1) WO2010063823A1 (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2686420B1 (en) * 2011-03-18 2017-03-01 New York Blood Center, Inc. Megakaryocyte and platelet production from stem cells
GB201210857D0 (en) 2012-06-19 2012-08-01 Cambridge Entpr Ltd Transcription factor mediated programming towards megakaryocytes
CA3177929A1 (en) 2012-12-21 2014-06-26 Astellas Institute For Regenerative Medicine Methods for production of platelets from pluripotent stem cells and compositions thereof
US9795965B2 (en) 2013-01-03 2017-10-24 Brigham And Women's Hospital, Inc. System and method for a biomimetic fluid processing
AU2014352015B2 (en) * 2013-11-19 2019-10-03 Espci Paristech Fluidic device for producing platelets
JP2015181406A (ja) * 2014-03-24 2015-10-22 東レエンジニアリング株式会社 血小板産生装置および血小板産生方法
EP3126484B1 (en) 2014-03-31 2020-09-23 Brigham and Women's Hospital, Inc. Systems and methods for biomimetic fluid processing
US10538738B2 (en) * 2014-05-19 2020-01-21 Eleftherios Papoutsakis Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells
JP6883173B2 (ja) * 2015-05-12 2021-06-09 ヘモストッド エスエー 改善された血小板産生のための薬理学的特徴およびマイクロ流体特徴の組み合わせ
WO2016204256A1 (ja) * 2015-06-16 2016-12-22 国立大学法人京都大学 高機能性血小板の製造方法
CN108289914B (zh) * 2015-09-08 2022-06-14 布里格姆女子医院有限公司 用于产生血小板的系统和方法
EP3351627A4 (en) * 2015-09-15 2019-03-27 Megakaryon Corporation PROCESS FOR THE PRODUCTION OF BLOOD PLATES ON THE BASIS OF A ROTATING STIRRING CULTURING METHOD
CN108135940B (zh) * 2015-10-14 2022-04-15 株式会社美加细胞 纯化血小板的制造方法
SG11201803591UA (en) * 2015-11-02 2018-05-30 Megakaryon Corp Method for producing platelets using reciprocating stirring device
WO2018237061A1 (en) * 2017-06-20 2018-12-27 Northwestern University Microfluidic platelet bioreactor device and systems
AU2019205942B2 (en) 2018-01-05 2025-05-15 Platelet Biogenesis, Inc. Compositions and methods for producing megakaryocytes
US12403161B2 (en) 2018-06-29 2025-09-02 Stellular Bio, Inc. Compositions for drug delivery and methods of use thereof
AU2019305092A1 (en) 2018-07-19 2021-03-11 Platelet Biogenesis, Inc. Stacked recirculating bioreactor
FR3101885B1 (fr) * 2019-10-11 2024-11-08 Francais Du Sang Ets Systeme pour la liberation de plaquettes et procede de liberation de plaquettes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344560A (en) * 1979-11-02 1982-08-17 Asahi Kasei Kogyo Kabushiki Kaisha Container, apparatus and method for separating platelets
DE19956156A1 (de) * 1999-11-23 2001-06-13 Univ Eberhard Karls Verfahren zur Aufbereitung eines Präparates von Thrombozyten und Thrombozytenpräparat
EP1369128A1 (en) * 2002-06-07 2003-12-10 Procorde GmbH Inhibitors of glycoprotein VI and their therapeutic use
AU2005302258B2 (en) * 2004-11-01 2010-10-21 Wisconsin Alumni Research Foundation Platelets from stem cells
PL1836500T3 (pl) * 2005-01-14 2010-12-31 Ablynx Nv Sposoby i testy do rozróżniania między różnymi postaciami chorób i zaburzeń cechujących się małopłytkowością i/lub samoistną interakcją między czynnikiem von Willebranda (vWF) a płytkami krwi
JP5419076B2 (ja) * 2008-05-15 2014-02-19 旭化成メディカル株式会社 血小板の誘導方法

Also Published As

Publication number Publication date
US20120014933A1 (en) 2012-01-19
CA2745268A1 (en) 2010-06-10
EP2352815B1 (en) 2016-02-10
BRPI0922710A2 (pt) 2016-01-05
SI2352815T1 (sl) 2016-10-28
HUE027112T2 (en) 2016-08-29
CN102300984A (zh) 2011-12-28
JP2012510804A (ja) 2012-05-17
DK2352815T3 (en) 2016-05-17
HRP20160404T8 (hr) 2016-07-01
US9012221B2 (en) 2015-04-21
HRP20160404T1 (hr) 2016-06-17
CN104087552A (zh) 2014-10-08
JP5863459B2 (ja) 2016-02-16
CA2745268C (en) 2018-11-13
ES2569610T3 (es) 2016-05-11
BRPI0922710A8 (pt) 2018-06-26
CN102300984B (zh) 2014-06-04
EP2352815A1 (en) 2011-08-10
HK1165491A1 (en) 2012-10-05
AU2009324042B2 (en) 2014-12-04
CY1117452T1 (el) 2017-04-26
AU2009324042A1 (en) 2011-07-07
PL2352815T3 (pl) 2016-07-29
WO2010063823A1 (en) 2010-06-10

Similar Documents

Publication Publication Date Title
SMT201600131B (it) Procedimento per la produzione di piastrine
SMT201600254B (it) Procedimento per la preparazione di idromagnesite
SMAP200900085A (it) 3-imidazolil-indoli per il trattamento di malattieproliferative
DK3216802T3 (da) Produktionsfremgangsmåde
IT1395068B1 (it) Processo per la produzione di galatto-oligosaccaridi ultrapuri
IT1401129B1 (it) Processo per la sintesi di composti benzotiadiazolici
IT1392910B1 (it) Procedimento per la produzione di lipidi da biomassa
IT1393061B1 (it) Procedimento integrato per la produzione di bio-olio da microrganismi
EP2374802A4 (en) INHIBITOR OF KYNURENINE PRODUCTION
SMT201500152B (it) Procedimento per la produzione di funghi
IT1397503B1 (it) Processo per la preparazione di olopatadina
IT1393062B1 (it) Procedimento per la preparazione di gemcitabina cloridrato
IT1397895B1 (it) Procedimento per la compensazione di quadratura
IT1394416B1 (it) Apparato per la realizzazione di pannelli tamburati.
ITMI20080195A1 (it) Procedimento per la preparazione di solifenacin
IT1399353B1 (it) Procedimento per la produzione di cioccolata
BRPI0913890A2 (pt) Método para produção de ácido 3-metil-2tiofenocarboxílico
ITMI20081084A1 (it) Processo per la preparazione di brinzolamide
ITTO20110857A1 (it) Procedimento per la produzione di cicloesanonossina.
IT1391769B1 (it) Apparato per la formatura di pannellature
IT1392206B1 (it) Apparato per la produzione di spazzole o scope
IT1394292B1 (it) Procedimento per la sintesi di pregabalina
IT1394299B1 (it) Procedimento per la preparazione di sevelamer
IT1391776B1 (it) Procedimento per la preparazione di dexlansoprazolo
ITMI20080011A1 (it) Procedimento per la preparazione di diacereina