PL2352815T3 - Sposób wytwarzania płytek krwi - Google Patents

Sposób wytwarzania płytek krwi

Info

Publication number
PL2352815T3
PL2352815T3 PL09768362T PL09768362T PL2352815T3 PL 2352815 T3 PL2352815 T3 PL 2352815T3 PL 09768362 T PL09768362 T PL 09768362T PL 09768362 T PL09768362 T PL 09768362T PL 2352815 T3 PL2352815 T3 PL 2352815T3
Authority
PL
Poland
Prior art keywords
producing platelets
platelets
producing
Prior art date
Application number
PL09768362T
Other languages
English (en)
Inventor
Dominique Baruch
Elisabeth Cramer-Borde
Claire Dunois-Larde
Original Assignee
Inst Nat Sante Rech Med
Hopitaux Paris Assist Publique
Univ Paris Descartes
Luniversite De Versailles Saint Quentin En Yvelines
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Hopitaux Paris Assist Publique, Univ Paris Descartes, Luniversite De Versailles Saint Quentin En Yvelines filed Critical Inst Nat Sante Rech Med
Publication of PL2352815T3 publication Critical patent/PL2352815T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/145—Thrombopoietin [TPO]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
PL09768362T 2008-12-04 2009-12-04 Sposób wytwarzania płytek krwi PL2352815T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08305881 2008-12-04
PCT/EP2009/066401 WO2010063823A1 (en) 2008-12-04 2009-12-04 Method for producing platelets
EP09768362.7A EP2352815B1 (en) 2008-12-04 2009-12-04 Method for producing platelets

Publications (1)

Publication Number Publication Date
PL2352815T3 true PL2352815T3 (pl) 2016-07-29

Family

ID=40756593

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09768362T PL2352815T3 (pl) 2008-12-04 2009-12-04 Sposób wytwarzania płytek krwi

Country Status (16)

Country Link
US (1) US9012221B2 (pl)
EP (1) EP2352815B1 (pl)
JP (1) JP5863459B2 (pl)
CN (2) CN104087552A (pl)
AU (1) AU2009324042B2 (pl)
BR (1) BRPI0922710A8 (pl)
CA (1) CA2745268C (pl)
CY (1) CY1117452T1 (pl)
DK (1) DK2352815T3 (pl)
ES (1) ES2569610T3 (pl)
HR (1) HRP20160404T8 (pl)
HU (1) HUE027112T2 (pl)
PL (1) PL2352815T3 (pl)
SI (1) SI2352815T1 (pl)
SM (1) SMT201600131B (pl)
WO (1) WO2010063823A1 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2686420B1 (en) * 2011-03-18 2017-03-01 New York Blood Center, Inc. Megakaryocyte and platelet production from stem cells
GB201210857D0 (en) 2012-06-19 2012-08-01 Cambridge Entpr Ltd Transcription factor mediated programming towards megakaryocytes
CA3177929A1 (en) 2012-12-21 2014-06-26 Astellas Institute For Regenerative Medicine Methods for production of platelets from pluripotent stem cells and compositions thereof
US9795965B2 (en) 2013-01-03 2017-10-24 Brigham And Women's Hospital, Inc. System and method for a biomimetic fluid processing
AU2014352015B2 (en) * 2013-11-19 2019-10-03 Espci Paristech Fluidic device for producing platelets
JP2015181406A (ja) * 2014-03-24 2015-10-22 東レエンジニアリング株式会社 血小板産生装置および血小板産生方法
EP3126484B1 (en) 2014-03-31 2020-09-23 Brigham and Women's Hospital, Inc. Systems and methods for biomimetic fluid processing
US10538738B2 (en) * 2014-05-19 2020-01-21 Eleftherios Papoutsakis Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells
JP6883173B2 (ja) * 2015-05-12 2021-06-09 ヘモストッド エスエー 改善された血小板産生のための薬理学的特徴およびマイクロ流体特徴の組み合わせ
WO2016204256A1 (ja) * 2015-06-16 2016-12-22 国立大学法人京都大学 高機能性血小板の製造方法
CN108289914B (zh) * 2015-09-08 2022-06-14 布里格姆女子医院有限公司 用于产生血小板的系统和方法
EP3351627A4 (en) * 2015-09-15 2019-03-27 Megakaryon Corporation PROCESS FOR THE PRODUCTION OF BLOOD PLATES ON THE BASIS OF A ROTATING STIRRING CULTURING METHOD
CN108135940B (zh) * 2015-10-14 2022-04-15 株式会社美加细胞 纯化血小板的制造方法
SG11201803591UA (en) * 2015-11-02 2018-05-30 Megakaryon Corp Method for producing platelets using reciprocating stirring device
WO2018237061A1 (en) * 2017-06-20 2018-12-27 Northwestern University Microfluidic platelet bioreactor device and systems
AU2019205942B2 (en) 2018-01-05 2025-05-15 Platelet Biogenesis, Inc. Compositions and methods for producing megakaryocytes
US12403161B2 (en) 2018-06-29 2025-09-02 Stellular Bio, Inc. Compositions for drug delivery and methods of use thereof
AU2019305092A1 (en) 2018-07-19 2021-03-11 Platelet Biogenesis, Inc. Stacked recirculating bioreactor
FR3101885B1 (fr) * 2019-10-11 2024-11-08 Francais Du Sang Ets Systeme pour la liberation de plaquettes et procede de liberation de plaquettes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344560A (en) * 1979-11-02 1982-08-17 Asahi Kasei Kogyo Kabushiki Kaisha Container, apparatus and method for separating platelets
DE19956156A1 (de) * 1999-11-23 2001-06-13 Univ Eberhard Karls Verfahren zur Aufbereitung eines Präparates von Thrombozyten und Thrombozytenpräparat
EP1369128A1 (en) * 2002-06-07 2003-12-10 Procorde GmbH Inhibitors of glycoprotein VI and their therapeutic use
AU2005302258B2 (en) * 2004-11-01 2010-10-21 Wisconsin Alumni Research Foundation Platelets from stem cells
PL1836500T3 (pl) * 2005-01-14 2010-12-31 Ablynx Nv Sposoby i testy do rozróżniania między różnymi postaciami chorób i zaburzeń cechujących się małopłytkowością i/lub samoistną interakcją między czynnikiem von Willebranda (vWF) a płytkami krwi
JP5419076B2 (ja) * 2008-05-15 2014-02-19 旭化成メディカル株式会社 血小板の誘導方法

Also Published As

Publication number Publication date
US20120014933A1 (en) 2012-01-19
CA2745268A1 (en) 2010-06-10
EP2352815B1 (en) 2016-02-10
BRPI0922710A2 (pt) 2016-01-05
SI2352815T1 (sl) 2016-10-28
HUE027112T2 (en) 2016-08-29
CN102300984A (zh) 2011-12-28
JP2012510804A (ja) 2012-05-17
DK2352815T3 (en) 2016-05-17
HRP20160404T8 (hr) 2016-07-01
US9012221B2 (en) 2015-04-21
HRP20160404T1 (hr) 2016-06-17
CN104087552A (zh) 2014-10-08
JP5863459B2 (ja) 2016-02-16
CA2745268C (en) 2018-11-13
ES2569610T3 (es) 2016-05-11
BRPI0922710A8 (pt) 2018-06-26
CN102300984B (zh) 2014-06-04
EP2352815A1 (en) 2011-08-10
HK1165491A1 (en) 2012-10-05
AU2009324042B2 (en) 2014-12-04
CY1117452T1 (el) 2017-04-26
AU2009324042A1 (en) 2011-07-07
SMT201600131B (it) 2016-07-01
WO2010063823A1 (en) 2010-06-10

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