HK1158189A1 - 嗎福啉基嘌呤衍生物 - Google Patents

嗎福啉基嘌呤衍生物

Info

Publication number
HK1158189A1
HK1158189A1 HK11112477.4A HK11112477A HK1158189A1 HK 1158189 A1 HK1158189 A1 HK 1158189A1 HK 11112477 A HK11112477 A HK 11112477A HK 1158189 A1 HK1158189 A1 HK 1158189A1
Authority
HK
Hong Kong
Prior art keywords
morpholinopurine
derivative
morpholinopurine derivative
Prior art date
Application number
HK11112477.4A
Other languages
English (en)
Inventor
Kiyoshi Nakayama
Masaki Setoguchi
Yuichi Tominaga
Masanori Saitou
Takashi Odagiri
Kazuyuki Sugita
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of HK1158189A1 publication Critical patent/HK1158189A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK11112477.4A 2008-10-14 2011-11-18 嗎福啉基嘌呤衍生物 HK1158189A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008264797 2008-10-14
JP2009121690 2009-05-20
PCT/JP2009/067738 WO2010044401A1 (ja) 2008-10-14 2009-10-13 モルホリノプリン誘導体

Publications (1)

Publication Number Publication Date
HK1158189A1 true HK1158189A1 (zh) 2012-07-13

Family

ID=42106564

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11112477.4A HK1158189A1 (zh) 2008-10-14 2011-11-18 嗎福啉基嘌呤衍生物

Country Status (22)

Country Link
US (2) US8097622B2 (zh)
EP (1) EP2336132B1 (zh)
JP (1) JP5090423B2 (zh)
KR (1) KR101614976B1 (zh)
CN (1) CN102245607B (zh)
AU (1) AU2009304789B2 (zh)
BR (1) BRPI0920199A2 (zh)
CA (1) CA2740471C (zh)
CO (1) CO6362009A2 (zh)
DK (1) DK2336132T3 (zh)
ES (1) ES2452541T3 (zh)
HK (1) HK1158189A1 (zh)
IL (1) IL212278A (zh)
MX (1) MX2011003490A (zh)
MY (1) MY156456A (zh)
NZ (1) NZ592761A (zh)
PL (1) PL2336132T3 (zh)
PT (1) PT2336132E (zh)
RU (1) RU2490269C2 (zh)
TW (1) TWI378933B (zh)
WO (1) WO2010044401A1 (zh)
ZA (1) ZA201102449B (zh)

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CN102260263A (zh) * 2010-05-26 2011-11-30 四川大学 一类二苯胺基嘌呤衍生物及制备方法和医药用途
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ES2911522T3 (es) 2016-12-02 2022-05-19 Daiichi Sankyo Co Ltd Novedosa endo-ß-n-acetilglucosaminidasa
EP3360865A1 (en) 2017-02-13 2018-08-15 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for the preparation of cyclopropyldiketopiperazines, and of a key intermediate of ds-5272
TWI837231B (zh) 2018-11-29 2024-04-01 日商第一三共股份有限公司 含有ｅｚｈ１／２雙重抑制劑之醫藥組合及其用途
CN113368114B (zh) * 2020-03-10 2022-04-22 四川大学 一种吗啉嘧啶类化合物的抗肿瘤应用
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Also Published As

Publication number Publication date
CA2740471C (en) 2013-09-17
TW201018690A (en) 2010-05-16
AU2009304789A1 (en) 2010-04-22
NZ592761A (en) 2012-05-25
EP2336132B1 (en) 2014-01-01
MY156456A (en) 2016-02-26
PT2336132E (pt) 2014-04-02
PL2336132T3 (pl) 2014-06-30
IL212278A0 (en) 2011-06-30
TWI378933B (en) 2012-12-11
CN102245607B (zh) 2014-07-02
CA2740471A1 (en) 2010-04-22
WO2010044401A1 (ja) 2010-04-22
EP2336132A4 (en) 2012-03-21
US20120071476A1 (en) 2012-03-22
AU2009304789B2 (en) 2012-04-05
JP2011001339A (ja) 2011-01-06
JP5090423B2 (ja) 2012-12-05
MX2011003490A (es) 2011-04-21
ES2452541T3 (es) 2014-04-01
DK2336132T3 (da) 2014-04-07
EP2336132A1 (en) 2011-06-22
US8097622B2 (en) 2012-01-17
US8309546B2 (en) 2012-11-13
US20100130492A1 (en) 2010-05-27
CN102245607A (zh) 2011-11-16
RU2490269C2 (ru) 2013-08-20
RU2011119525A (ru) 2012-11-27
IL212278A (en) 2016-07-31
ZA201102449B (en) 2011-12-28
CO6362009A2 (es) 2012-01-20
KR101614976B1 (ko) 2016-04-22
KR20110067038A (ko) 2011-06-20
BRPI0920199A2 (pt) 2019-09-24

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