HK1154352A1 - A blocking monoclonal antibody to the human alpha1 i-domain of vla-1, and its use for the treatment of inflammatory disorders 1 i- vla-1 - Google Patents

A blocking monoclonal antibody to the human alpha1 i-domain of vla-1, and its use for the treatment of inflammatory disorders 1 i- vla-1

Info

Publication number
HK1154352A1
HK1154352A1 HK11108559.3A HK11108559A HK1154352A1 HK 1154352 A1 HK1154352 A1 HK 1154352A1 HK 11108559 A HK11108559 A HK 11108559A HK 1154352 A1 HK1154352 A1 HK 1154352A1
Authority
HK
Hong Kong
Prior art keywords
vla
domain
treatment
monoclonal antibody
inflammatory disorders
Prior art date
Application number
HK11108559.3A
Other languages
English (en)
Chinese (zh)
Inventor
Fougerolles Antonin De
Philip Gotwals
Roy R Lobb
Victor E Koteliansky
Original Assignee
Biogen Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Ma Inc filed Critical Biogen Ma Inc
Publication of HK1154352A1 publication Critical patent/HK1154352A1/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Hematology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
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  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
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HK11108559.3A 1999-06-01 2011-08-15 A blocking monoclonal antibody to the human alpha1 i-domain of vla-1, and its use for the treatment of inflammatory disorders 1 i- vla-1 HK1154352A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13703899P 1999-06-01 1999-06-01
US18533600P 2000-02-29 2000-02-29

Publications (1)

Publication Number Publication Date
HK1154352A1 true HK1154352A1 (en) 2012-04-20

Family

ID=26834850

Family Applications (2)

Application Number Title Priority Date Filing Date
HK02105185.2A HK1043320A1 (zh) 1999-06-01 2002-07-12 Vla-1的一種阻塞性單系抗體，以及其治療炎性失調的功用
HK11108559.3A HK1154352A1 (en) 1999-06-01 2011-08-15 A blocking monoclonal antibody to the human alpha1 i-domain of vla-1, and its use for the treatment of inflammatory disorders 1 i- vla-1

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK02105185.2A HK1043320A1 (zh) 1999-06-01 2002-07-12 Vla-1的一種阻塞性單系抗體，以及其治療炎性失調的功用

Country Status (28)

Country Link
US (5) US6955810B2 (xx)
EP (3) EP1488806B1 (xx)
JP (6) JP4817503B2 (xx)
CN (1) CN1309419C (xx)
AU (2) AU783989B2 (xx)
BG (1) BG65579B1 (xx)
BR (1) BR0011250A (xx)
CA (1) CA2375827C (xx)
CY (1) CY1116042T1 (xx)
CZ (1) CZ300710B6 (xx)
DK (2) DK2314315T3 (xx)
EA (1) EA011384B1 (xx)
EE (1) EE200100651A (xx)
ES (2) ES2557768T3 (xx)
GE (1) GEP20063774B (xx)
HK (2) HK1043320A1 (xx)
HU (1) HUP0202568A3 (xx)
IL (2) IL146508A0 (xx)
IS (1) IS6179A (xx)
MX (1) MXPA01012388A (xx)
NO (1) NO20015864L (xx)
NZ (1) NZ515686A (xx)
PT (2) PT2314315E (xx)
SI (2) SI1488806T1 (xx)
SK (1) SK17232001A3 (xx)
TR (1) TR200103432T2 (xx)
WO (1) WO2000072881A1 (xx)
YU (1) YU85501A (xx)

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