HK1147275A1 - Axl antibodies axl - Google Patents
Axl antibodies axlInfo
- Publication number
- HK1147275A1 HK1147275A1 HK11101502.6A HK11101502A HK1147275A1 HK 1147275 A1 HK1147275 A1 HK 1147275A1 HK 11101502 A HK11101502 A HK 11101502A HK 1147275 A1 HK1147275 A1 HK 1147275A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- axl
- antibodies
- axl antibodies
- antibodies axl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07021931 | 2007-11-12 | ||
PCT/EP2008/009548 WO2009062690A1 (en) | 2007-11-12 | 2008-11-12 | Axl antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1147275A1 true HK1147275A1 (en) | 2011-08-05 |
Family
ID=40280763
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11101502.6A HK1147275A1 (en) | 2007-11-12 | 2011-02-16 | Axl antibodies axl |
HK13112909.0A HK1185622A1 (en) | 2007-11-12 | 2013-11-19 | Axl antibodies axl |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK13112909.0A HK1185622A1 (en) | 2007-11-12 | 2013-11-19 | Axl antibodies axl |
Country Status (20)
Country | Link |
---|---|
US (1) | US8933202B2 (ja) |
EP (2) | EP2220121B1 (ja) |
JP (2) | JP5769969B2 (ja) |
KR (1) | KR20100097684A (ja) |
CN (2) | CN101939336B (ja) |
AU (1) | AU2008323206B2 (ja) |
BR (1) | BRPI0820073A2 (ja) |
CA (1) | CA2705164A1 (ja) |
CO (1) | CO6280499A2 (ja) |
DK (1) | DK2220121T3 (ja) |
ES (1) | ES2556214T3 (ja) |
HK (2) | HK1147275A1 (ja) |
IL (1) | IL205607A0 (ja) |
MX (1) | MX2010005031A (ja) |
MY (1) | MY155621A (ja) |
NZ (2) | NZ585465A (ja) |
RU (1) | RU2506276C2 (ja) |
SG (2) | SG186000A1 (ja) |
WO (1) | WO2009062690A1 (ja) |
ZA (1) | ZA201003397B (ja) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0820073A2 (pt) * | 2007-11-12 | 2015-06-23 | U3 Pharma Gmbh | Anticorpos anti-axl |
SG188134A1 (en) | 2007-11-15 | 2013-03-28 | Chugai Pharmaceutical Co Ltd | Monoclonal antibody capable of binding to anexelekto, and use thereof |
MA33208B1 (fr) | 2009-03-25 | 2012-04-02 | Genentech Inc | Anticorps anti-fgfr3 et procédés d'utilisation de ceux-ci |
EP2270053A1 (en) * | 2009-05-11 | 2011-01-05 | U3 Pharma GmbH | Humanized AXL antibodies |
CA2759836A1 (en) * | 2009-05-11 | 2010-11-18 | U3 Pharma Gmbh | Humanized axl antibodies |
TW201041595A (en) | 2009-05-15 | 2010-12-01 | Chugai Pharmaceutical Co Ltd | Anti-axl antibody |
AR077595A1 (es) | 2009-07-27 | 2011-09-07 | Genentech Inc | Tratamientos de combinacion |
US9005926B2 (en) | 2009-10-02 | 2015-04-14 | Biogen Idec Ma Inc. | Methods of preventing and removing trisulfide bonds |
PT3241840T (pt) * | 2010-01-22 | 2022-10-13 | Univ Leland Stanford Junior | Inibição da sinalização de axl em terapêutica anti-metastática |
CN101858917B (zh) * | 2010-06-02 | 2013-03-27 | 成都创宜生物科技有限公司 | Axl单克隆抗体的应用及以Axl为检测指标的胎膜早破检测试剂盒和制备方法 |
AR082017A1 (es) * | 2010-06-18 | 2012-11-07 | Genentech Inc | Anticuerpos anti-axl (receptor de tirosina quinasas) y metodos de uso |
EP2670426B1 (en) | 2011-01-31 | 2017-05-10 | The General Hospital Corporation | Multimodal trail molecules and uses in cellular therapies |
WO2012158551A1 (en) | 2011-05-13 | 2012-11-22 | Biogen Idec Ma Inc. | Methods of preventing and removing trisulfide bonds |
EP2723376B1 (en) * | 2011-06-22 | 2018-12-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-axl antibodies and uses thereof |
BR112013032899A2 (pt) | 2011-06-22 | 2017-01-24 | Inserm Inst Nat De La Santé Et De La Rech Médicale | anticorpos anti-axl e utilizações dos mesmos |
EP2748197A2 (en) | 2011-08-26 | 2014-07-02 | Merrimack Pharmaceuticals, Inc. | Tandem fc bispecific antibodies |
EP2589609A1 (en) * | 2011-11-03 | 2013-05-08 | Pierre Fabre Medicament | Antigen binding protein and its use as addressing product for the treatment of cancer |
EP2877572B1 (en) | 2012-07-24 | 2018-11-28 | The General Hospital Corporation | Oncolytic virus therapy for resistant tumors |
EP2890720B1 (en) * | 2012-08-30 | 2019-07-17 | The General Hospital Corporation | Compositions and methods for treating cancer |
US10669324B2 (en) | 2012-10-30 | 2020-06-02 | Suppremol Gmbh | Vector encoding an Fc gamma receptor IIB protein and composition of the encoded protein |
JP6195716B2 (ja) * | 2013-02-15 | 2017-09-13 | 富士レビオ株式会社 | 抗癌剤耐性診断マーカー |
WO2014138449A1 (en) | 2013-03-06 | 2014-09-12 | Merrimack Pharmaceuticals, Inc. | Anti-c-met tandem fc bispecific antibodies |
EP2837637A1 (en) * | 2013-08-16 | 2015-02-18 | SuppreMol GmbH | Novel anti-FcyRIIB IgG-type antibody |
GB201410825D0 (en) | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
GB201410826D0 (en) | 2014-06-18 | 2014-07-30 | Bergenbio As | Anti-axl antibodies |
AU2015308818B2 (en) | 2014-08-28 | 2021-02-25 | Bioatla Llc | Conditionally active chimeric antigen receptors for modified T-cells |
US10398774B2 (en) * | 2014-12-09 | 2019-09-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Human monoclonal antibodies against AXL |
JP6931609B2 (ja) | 2014-12-18 | 2021-09-08 | ベルゲン テクノロジオーヴァーフォリング エイエス | 抗Axlアンタゴニスト抗体 |
GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
EP3297662A4 (en) | 2015-05-18 | 2019-03-13 | Agensys, Inc. | ANTIBODY BINDING TO AXL PROTEINS |
EP3297663A4 (en) * | 2015-05-18 | 2018-12-19 | Agensys, Inc. | Antibodies that bind to axl proteins |
GB201509338D0 (en) | 2015-05-29 | 2015-07-15 | Bergenbio As | Combination therapy |
PT3319993T (pt) | 2015-07-10 | 2020-04-22 | Genmab As | Conjugados de anticorpo-fármaco específicos de axl para tratamento de cancro |
CA3021086C (en) | 2016-04-15 | 2023-10-17 | Bioatla, Llc | Anti-axl antibodies, antibody fragments and their immunoconjugates and uses thereof |
EP3455261B1 (en) | 2016-05-13 | 2022-08-03 | BioAtla, Inc. | Anti-ror2 antibodies, antibody fragments, their immunoconjugates and uses thereof |
GB201610902D0 (en) * | 2016-06-22 | 2016-08-03 | Bergen Teknologioverforing As And Bergenbio As | Anti-Axl Antagonistic Antibodies |
SG10202107808SA (en) | 2017-01-18 | 2021-08-30 | F1 Oncology Inc | Chimeric antigen receptors against axl or ror2 and methods of use thereof |
PL3612234T3 (pl) | 2017-04-20 | 2024-09-02 | Adc Therapeutics Sa | Terapia skojarzona z koniugatem anty-AXL przeciwciało-lek |
CN110540592B (zh) * | 2018-05-29 | 2022-08-09 | 杭州尚健生物技术有限公司 | 结合axl蛋白的抗体及其应用 |
CN109160941B (zh) * | 2018-09-29 | 2020-09-04 | 未名生物医药有限公司 | 蛋白序列17e11及其用途 |
GB201912059D0 (en) | 2019-08-22 | 2019-10-09 | Bergenbio As | Combaination therapy of a patient subgroup |
JP2023509760A (ja) | 2020-01-08 | 2023-03-09 | シンシス セラピューティクス,インコーポレイテッド | Alk5阻害剤複合体およびその使用 |
GB202004189D0 (en) | 2020-03-23 | 2020-05-06 | Bergenbio As | Combination therapy |
MX2022012576A (es) | 2020-04-08 | 2023-01-19 | Bergenbio Asa | Inhibidores de axl para terapia antiviral. |
GB202006072D0 (en) | 2020-04-24 | 2020-06-10 | Bergenbio Asa | Method of selecting patients for treatment with cmbination therapy |
GB202104037D0 (en) | 2021-03-23 | 2021-05-05 | Bergenbio Asa | Combination therapy |
WO2022261846A1 (zh) * | 2021-06-16 | 2022-12-22 | 上海鑫湾生物科技有限公司 | 靶向axl蛋白的抗体及其抗原结合片段、其制备方法和应用 |
CN116348497B (zh) * | 2023-01-05 | 2023-11-17 | 浙江时迈药业有限公司 | 针对axl的抗体及其用途 |
CN116715774B (zh) * | 2023-05-12 | 2023-11-24 | 武汉爱博泰克生物科技有限公司 | 针对人axl的兔单克隆抗体及其制备方法和应用 |
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2008
- 2008-11-12 BR BRPI0820073-4A patent/BRPI0820073A2/pt not_active IP Right Cessation
- 2008-11-12 MY MYPI2010002190A patent/MY155621A/en unknown
- 2008-11-12 NZ NZ585465A patent/NZ585465A/xx unknown
- 2008-11-12 KR KR1020107012747A patent/KR20100097684A/ko active IP Right Grant
- 2008-11-12 CA CA2705164A patent/CA2705164A1/en not_active Abandoned
- 2008-11-12 SG SG2012084026A patent/SG186000A1/en unknown
- 2008-11-12 RU RU2010123888/10A patent/RU2506276C2/ru not_active IP Right Cessation
- 2008-11-12 WO PCT/EP2008/009548 patent/WO2009062690A1/en active Application Filing
- 2008-11-12 EP EP08850452.7A patent/EP2220121B1/en active Active
- 2008-11-12 CN CN200880123225.9A patent/CN101939336B/zh not_active Expired - Fee Related
- 2008-11-12 MX MX2010005031A patent/MX2010005031A/es not_active Application Discontinuation
- 2008-11-12 JP JP2010532510A patent/JP5769969B2/ja not_active Expired - Fee Related
- 2008-11-12 US US12/742,546 patent/US8933202B2/en not_active Expired - Fee Related
- 2008-11-12 CN CN201310242420.6A patent/CN103275227B/zh not_active Expired - Fee Related
- 2008-11-12 ES ES08850452.7T patent/ES2556214T3/es active Active
- 2008-11-12 EP EP15162381.6A patent/EP2918605A1/en not_active Withdrawn
- 2008-11-12 AU AU2008323206A patent/AU2008323206B2/en not_active Ceased
- 2008-11-12 SG SG10201405835TA patent/SG10201405835TA/en unknown
- 2008-11-12 NZ NZ599628A patent/NZ599628A/xx unknown
- 2008-11-12 DK DK08850452.7T patent/DK2220121T3/en active
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2010
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2011
- 2011-02-16 HK HK11101502.6A patent/HK1147275A1/xx not_active IP Right Cessation
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Also Published As
Publication number | Publication date |
---|---|
BRPI0820073A2 (pt) | 2015-06-23 |
KR20100097684A (ko) | 2010-09-03 |
EP2220121B1 (en) | 2015-08-19 |
NZ585465A (en) | 2012-12-21 |
HK1185622A1 (en) | 2014-02-21 |
MX2010005031A (es) | 2010-06-25 |
CN103275227B (zh) | 2015-02-11 |
RU2506276C2 (ru) | 2014-02-10 |
JP2011505120A (ja) | 2011-02-24 |
SG186000A1 (en) | 2012-12-28 |
US8933202B2 (en) | 2015-01-13 |
IL205607A0 (en) | 2010-11-30 |
SG10201405835TA (en) | 2014-10-30 |
EP2918605A1 (en) | 2015-09-16 |
CN101939336A (zh) | 2011-01-05 |
AU2008323206B2 (en) | 2014-08-14 |
JP5769969B2 (ja) | 2015-08-26 |
JP2015221804A (ja) | 2015-12-10 |
CN103275227A (zh) | 2013-09-04 |
DK2220121T3 (en) | 2015-12-07 |
ZA201003397B (en) | 2011-04-28 |
WO2009062690A1 (en) | 2009-05-22 |
RU2010123888A (ru) | 2011-12-20 |
NZ599628A (en) | 2013-11-29 |
ES2556214T3 (es) | 2016-01-14 |
EP2220121A1 (en) | 2010-08-25 |
AU2008323206A1 (en) | 2009-05-22 |
CA2705164A1 (en) | 2009-05-22 |
MY155621A (en) | 2015-11-13 |
US20100330095A1 (en) | 2010-12-30 |
CN101939336B (zh) | 2014-05-14 |
CO6280499A2 (es) | 2011-05-20 |
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