HK1131140A1 - 取代的脯氨酰胺、及其用途 - Google Patents
取代的脯氨酰胺、及其用途Info
- Publication number
- HK1131140A1 HK1131140A1 HK09110801.9A HK09110801A HK1131140A1 HK 1131140 A1 HK1131140 A1 HK 1131140A1 HK 09110801 A HK09110801 A HK 09110801A HK 1131140 A1 HK1131140 A1 HK 1131140A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- prolinamides
- substituted
- substituted prolinamides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06113977 | 2006-05-16 | ||
| EP07102566 | 2007-02-16 | ||
| PCT/EP2007/054631 WO2007131982A2 (de) | 2006-05-16 | 2007-05-14 | Substituierte prolinamide, deren herstellung und deren verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1131140A1 true HK1131140A1 (zh) | 2010-01-15 |
Family
ID=38646563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK09110801.9A HK1131140A1 (zh) | 2006-05-16 | 2009-11-19 | 取代的脯氨酰胺、及其用途 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7807693B2 (zh) |
| EP (1) | EP2051975B1 (zh) |
| JP (1) | JP5263686B2 (zh) |
| KR (1) | KR101422456B1 (zh) |
| AR (1) | AR060945A1 (zh) |
| AU (1) | AU2007251614B2 (zh) |
| BR (1) | BRPI0711648A2 (zh) |
| CA (1) | CA2653753C (zh) |
| CL (1) | CL2007001391A1 (zh) |
| DK (1) | DK2051975T3 (zh) |
| EA (1) | EA200802210A1 (zh) |
| EC (1) | ECSP088824A (zh) |
| ES (1) | ES2395538T3 (zh) |
| HK (1) | HK1131140A1 (zh) |
| IL (1) | IL195245A (zh) |
| MX (1) | MX2008014499A (zh) |
| MY (1) | MY146623A (zh) |
| NO (1) | NO20084530L (zh) |
| NZ (1) | NZ573573A (zh) |
| PE (1) | PE20080702A1 (zh) |
| PL (1) | PL2051975T3 (zh) |
| TW (1) | TW200813047A (zh) |
| UY (1) | UY30352A1 (zh) |
| WO (1) | WO2007131982A2 (zh) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1975165A1 (de) | 2007-03-27 | 2008-10-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Substituierte Pyrrolidinamide, deren Herstellung und deren Verwendung als Arzneimittel |
| US8741890B2 (en) | 2007-11-15 | 2014-06-03 | Boehringer Ingelheim International Gmbh | Substituted amides, manufacturing and use thereof as medicaments |
| CA2719985A1 (en) * | 2008-03-31 | 2009-10-08 | Evotec Ag | Tetrahydronaphthyridines and aza derivatives thereof as histamine h3 receptor antagonists |
| GB201209138D0 (en) * | 2012-05-24 | 2012-07-04 | Ono Pharmaceutical Co | Compounds |
| WO2014127815A1 (en) | 2013-02-21 | 2014-08-28 | Boehringer Ingelheim International Gmbh | Dihydropteridinones i |
| JP6337750B2 (ja) * | 2013-11-22 | 2018-06-06 | 小野薬品工業株式会社 | 化合物 |
| PL3102576T3 (pl) | 2014-02-03 | 2019-12-31 | Vitae Pharmaceuticals, Llc | Dihydropirolopirydynowe inhibitory ror-gamma |
| MA53399B1 (fr) * | 2014-03-07 | 2022-10-31 | Biocryst Pharm Inc | Pyrazoles substitués en tant qu`inhibiteurs de la kallicréine plasmatique humaine |
| UA118989C2 (uk) | 2014-10-14 | 2019-04-10 | Вітае Фармасьютікалс, Інк. | Дигідропіролопіридинові інгібітори ror-гамма |
| US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
| US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| EP3078378B1 (en) | 2015-04-08 | 2020-06-24 | Vaiomer | Use of factor xa inhibitors for regulating glycemia |
| WO2017024018A1 (en) | 2015-08-05 | 2017-02-09 | Vitae Pharmaceuticals, Inc. | Modulators of ror-gamma |
| MA53943A (fr) | 2015-11-20 | 2021-08-25 | Vitae Pharmaceuticals Llc | Modulateurs de ror-gamma |
| TWI757266B (zh) | 2016-01-29 | 2022-03-11 | 美商維它藥物有限責任公司 | ＲＯＲ－γ調節劑 |
| US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
| CN115716826A (zh) | 2017-07-24 | 2023-02-28 | 生命医药有限责任公司 | RORγ的抑制剂 |
| CN114646701B (zh) * | 2022-03-01 | 2023-09-29 | 浙江国邦药业有限公司 | 一种l-脯氨酰胺中有关物质的hplc测试方法 |
| WO2024214038A1 (en) * | 2023-04-14 | 2024-10-17 | Pfizer Inc. | Glucose-dependent insulinotropic polypeptide receptor antagonists and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7030141B2 (en) | 2001-11-29 | 2006-04-18 | Christopher Franklin Bigge | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade |
| JP3975254B2 (ja) * | 2002-07-25 | 2007-09-12 | 日野自動車株式会社 | チャイルドシート用アンカの取付構造 |
| ES2325077T3 (es) | 2003-04-03 | 2009-08-25 | Merck Patent Gmbh | Derivados de 1-(fenilamida)-2-(4-(3-oxo-morfolin-4-il)-fenilamida) del acido pirrolidin-1,2-dicarboxilico y compuestos emparentados como inhibidores del factor de la coagulacion xa, para el tratamiento de las enfermedades tromboembolicas. |
| DE10329457A1 (de) | 2003-04-03 | 2005-01-20 | Merck Patent Gmbh | Ethinylprolinderivate |
| MXPA05013536A (es) | 2003-06-18 | 2006-03-09 | Merck Patent Gmbh | Derivados de etinilprolina. |
| ES2223277B1 (es) | 2003-06-19 | 2006-03-01 | Fernando Bouffard Fita | Composicion anestesica para administracion topica. |
| DE10358814A1 (de) * | 2003-12-16 | 2005-07-21 | Merck Patent Gmbh | Prolinylarylacetamide |
| DE102004014945A1 (de) | 2004-03-26 | 2005-10-13 | Merck Patent Gmbh | Prolinylderivate |
| US7453002B2 (en) * | 2004-06-15 | 2008-11-18 | Bristol-Myers Squibb Company | Five-membered heterocycles useful as serine protease inhibitors |
| DE102004045796A1 (de) | 2004-09-22 | 2006-03-23 | Merck Patent Gmbh | Arzneimittel enthaltend Carbonylverbindungen sowie deren Verwendung |
| JP2008535887A (ja) | 2005-04-11 | 2008-09-04 | グラクソ グループ リミテッド | 第Ｘａ因子阻害剤としての３−スルホニルアミノ−ピロリジン−２−オン誘導体 |
| BRPI0613045A2 (pt) | 2005-07-15 | 2010-12-14 | Hoffmann La Roche | aminas cÍclicas fundidas a heteroarila |
-
2007
- 2007-05-14 AU AU2007251614A patent/AU2007251614B2/en not_active Ceased
- 2007-05-14 MX MX2008014499A patent/MX2008014499A/es active IP Right Grant
- 2007-05-14 WO PCT/EP2007/054631 patent/WO2007131982A2/de active Application Filing
- 2007-05-14 ES ES07729083T patent/ES2395538T3/es active Active
- 2007-05-14 NZ NZ573573A patent/NZ573573A/en not_active IP Right Cessation
- 2007-05-14 BR BRPI0711648-9A patent/BRPI0711648A2/pt not_active IP Right Cessation
- 2007-05-14 KR KR1020087027907A patent/KR101422456B1/ko not_active IP Right Cessation
- 2007-05-14 EP EP07729083A patent/EP2051975B1/de active Active
- 2007-05-14 PL PL07729083T patent/PL2051975T3/pl unknown
- 2007-05-14 DK DK07729083.1T patent/DK2051975T3/da active
- 2007-05-14 EA EA200802210A patent/EA200802210A1/ru unknown
- 2007-05-14 CA CA2653753A patent/CA2653753C/en not_active Expired - Fee Related
- 2007-05-14 PE PE2007000580A patent/PE20080702A1/es not_active Application Discontinuation
- 2007-05-14 JP JP2009510435A patent/JP5263686B2/ja not_active Expired - Fee Related
- 2007-05-14 MY MYPI20084581A patent/MY146623A/en unknown
- 2007-05-15 CL CL2007001391A patent/CL2007001391A1/es unknown
- 2007-05-15 UY UY30352A patent/UY30352A1/es not_active Application Discontinuation
- 2007-05-15 TW TW096117145A patent/TW200813047A/zh unknown
- 2007-05-16 AR ARP070102101A patent/AR060945A1/es unknown
- 2007-05-16 US US11/749,204 patent/US7807693B2/en active Active
-
2008
- 2008-10-15 EC EC2008008824A patent/ECSP088824A/es unknown
- 2008-10-28 NO NO20084530A patent/NO20084530L/no not_active Application Discontinuation
- 2008-11-12 IL IL195245A patent/IL195245A/en not_active IP Right Cessation
-
2009
- 2009-11-19 HK HK09110801.9A patent/HK1131140A1/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL195245A (en) | 2012-09-24 |
| AU2007251614A1 (en) | 2007-11-22 |
| ECSP088824A (es) | 2008-11-27 |
| NO20084530L (no) | 2008-12-12 |
| US20080139605A1 (en) | 2008-06-12 |
| TW200813047A (en) | 2008-03-16 |
| ES2395538T3 (es) | 2013-02-13 |
| MX2008014499A (es) | 2008-11-27 |
| KR20090017523A (ko) | 2009-02-18 |
| US7807693B2 (en) | 2010-10-05 |
| PE20080702A1 (es) | 2008-07-10 |
| EP2051975A2 (de) | 2009-04-29 |
| UY30352A1 (es) | 2008-01-02 |
| PL2051975T3 (pl) | 2013-01-31 |
| WO2007131982A3 (de) | 2008-01-10 |
| CL2007001391A1 (es) | 2008-01-18 |
| DK2051975T3 (da) | 2012-10-15 |
| KR101422456B1 (ko) | 2014-07-23 |
| CA2653753C (en) | 2013-09-24 |
| CA2653753A1 (en) | 2007-11-22 |
| EA200802210A1 (ru) | 2009-06-30 |
| AR060945A1 (es) | 2008-07-23 |
| AU2007251614B2 (en) | 2013-01-17 |
| EP2051975B1 (de) | 2012-09-12 |
| WO2007131982A2 (de) | 2007-11-22 |
| BRPI0711648A2 (pt) | 2011-11-29 |
| IL195245A0 (en) | 2009-09-22 |
| NZ573573A (en) | 2011-10-28 |
| JP5263686B2 (ja) | 2013-08-14 |
| JP2009537483A (ja) | 2009-10-29 |
| MY146623A (en) | 2012-09-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1131140A1 (zh) | 取代的脯氨酰胺、及其用途 | |
| IL206127A0 (en) | Azolylmethyloxiranes, use thereof and agents containing the same | |
| SI2217578T1 (sl) | (1,2,4)triazolo(1,5-a)piridinske in (1,2,4)triazolo(1,5-c)pirimidinske spojine in njihova uporaba | |
| EP2153838A4 (en) | ANTI-NOROVIRUS AGENT AND COMPOSITION COMPRISING SAME | |
| EP2209394A4 (en) | Armtasche | |
| HK1131922A1 (en) | Phenylpropionamide compounds and the use thereof | |
| HK1130489A1 (zh) | 取代的喹喔啉型哌啶化合物及其用途 | |
| IL202073A0 (en) | Substituted oxazolidinones and the use thereof | |
| GB0616111D0 (en) | Agents, methods and uses | |
| EP1962635A4 (en) | LOAD REDUCTION FOR SHOULDER AND USE THEREOF | |
| GB0601471D0 (en) | The cardioprotector | |
| GB0520176D0 (en) | Use | |
| GB0511190D0 (en) | Use | |
| GB0526031D0 (en) | Use | |
| GB0502250D0 (en) | Use | |
| GB0502992D0 (en) | The ballcaster | |
| EP2192122A4 (en) | Dithiolopyrrolone compounds and their preparation and use | |
| GB0526032D0 (en) | Use | |
| IL194972A0 (en) | 2-alkoxy-3,4,5-trihydroxy-alkylamide- | |
| GB0608797D0 (en) | Novel agents and the use thereof | |
| ZA200805851B (en) | Stress-reducer for shoulder and the use thereof | |
| GB0602141D0 (en) | The turboramjet | |
| GB0511610D0 (en) | The motor-roll-off | |
| GB0612279D0 (en) | The sockball | |
| GB0604276D0 (en) | The t-stick |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20180514 |