NO20084530L - Substituerte prolinamider, deres produksjon og anvendelse som medikament - Google Patents
Substituerte prolinamider, deres produksjon og anvendelse som medikamentInfo
- Publication number
- NO20084530L NO20084530L NO20084530A NO20084530A NO20084530L NO 20084530 L NO20084530 L NO 20084530L NO 20084530 A NO20084530 A NO 20084530A NO 20084530 A NO20084530 A NO 20084530A NO 20084530 L NO20084530 L NO 20084530L
- Authority
- NO
- Norway
- Prior art keywords
- drug
- production
- prolinamides
- substituted prolinamides
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Det beskrives nye substituerte prolinamider med den generelle formel (I) hvor D, L, E, G, J, M, R3, R4, R5 og R13 er som definert i beskrivelsen, deres tautomerer, deres enantiomerer, deres diastereomerer, deres blandinger og deres salter, særlig deres fysiologisk akseptable salter, med uorganiske eller organiske syrer eller baser, som oppviser verdifulle egenskaper.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06113977 | 2006-05-16 | ||
EP07102566 | 2007-02-16 | ||
PCT/EP2007/054631 WO2007131982A2 (de) | 2006-05-16 | 2007-05-14 | Substituierte prolinamide, deren herstellung und deren verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20084530L true NO20084530L (no) | 2008-12-12 |
Family
ID=38646563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20084530A NO20084530L (no) | 2006-05-16 | 2008-10-28 | Substituerte prolinamider, deres produksjon og anvendelse som medikament |
Country Status (24)
Country | Link |
---|---|
US (1) | US7807693B2 (no) |
EP (1) | EP2051975B1 (no) |
JP (1) | JP5263686B2 (no) |
KR (1) | KR101422456B1 (no) |
AR (1) | AR060945A1 (no) |
AU (1) | AU2007251614B2 (no) |
BR (1) | BRPI0711648A2 (no) |
CA (1) | CA2653753C (no) |
CL (1) | CL2007001391A1 (no) |
DK (1) | DK2051975T3 (no) |
EA (1) | EA200802210A1 (no) |
EC (1) | ECSP088824A (no) |
ES (1) | ES2395538T3 (no) |
HK (1) | HK1131140A1 (no) |
IL (1) | IL195245A (no) |
MX (1) | MX2008014499A (no) |
MY (1) | MY146623A (no) |
NO (1) | NO20084530L (no) |
NZ (1) | NZ573573A (no) |
PE (1) | PE20080702A1 (no) |
PL (1) | PL2051975T3 (no) |
TW (1) | TW200813047A (no) |
UY (1) | UY30352A1 (no) |
WO (1) | WO2007131982A2 (no) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1975165A1 (de) | 2007-03-27 | 2008-10-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Substituierte Pyrrolidinamide, deren Herstellung und deren Verwendung als Arzneimittel |
WO2009063028A2 (en) | 2007-11-15 | 2009-05-22 | Boehringer Ingelheim International Gmbh | Substituted amides, manufacturing and use thereof as medicaments |
CN102046624A (zh) * | 2008-03-31 | 2011-05-04 | 埃沃特克股份有限公司 | 作为组胺h3受体拮抗剂的四氢萘啶及其氮杂衍生物 |
GB201209138D0 (en) * | 2012-05-24 | 2012-07-04 | Ono Pharmaceutical Co | Compounds |
WO2014127815A1 (en) | 2013-02-21 | 2014-08-28 | Boehringer Ingelheim International Gmbh | Dihydropteridinones i |
JP6337750B2 (ja) * | 2013-11-22 | 2018-06-06 | 小野薬品工業株式会社 | 化合物 |
SG11201606080SA (en) | 2014-02-03 | 2016-08-30 | Vitae Pharmaceuticals Inc | Dihydropyrrolopyridine inhibitors of ror-gamma |
CN113307772B (zh) * | 2014-03-07 | 2024-06-28 | 拜奥克里斯特制药公司 | 人类血浆激肽释放酶抑制剂 |
MY182454A (en) | 2014-10-14 | 2021-01-25 | Vitae Pharmaceuticals Llc | Dihydropyrrolopyridine inhibitors of ror-gamma |
US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
EP3078378B1 (en) | 2015-04-08 | 2020-06-24 | Vaiomer | Use of factor xa inhibitors for regulating glycemia |
ES2856931T3 (es) | 2015-08-05 | 2021-09-28 | Vitae Pharmaceuticals Llc | Moduladores de ROR-gamma |
US11008340B2 (en) | 2015-11-20 | 2021-05-18 | Vitae Pharmaceuticals, Llc | Modulators of ROR-gamma |
TW202220968A (zh) | 2016-01-29 | 2022-06-01 | 美商維它藥物有限責任公司 | ROR-γ調節劑 |
US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
WO2019023207A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF RORƳ |
CN114646701B (zh) * | 2022-03-01 | 2023-09-29 | 浙江国邦药业有限公司 | 一种l-脯氨酰胺中有关物质的hplc测试方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7030141B2 (en) * | 2001-11-29 | 2006-04-18 | Christopher Franklin Bigge | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade |
JP3975254B2 (ja) * | 2002-07-25 | 2007-09-12 | 日野自動車株式会社 | チャイルドシート用アンカの取付構造 |
DE10329457A1 (de) | 2003-04-03 | 2005-01-20 | Merck Patent Gmbh | Ethinylprolinderivate |
KR20050118708A (ko) | 2003-04-03 | 2005-12-19 | 메르크 파텐트 게엠베하 | 혈전-색전 질환의 치료에서 응고 인자 xa의 저해제로서사용하기 위한피롤리디노-1,2-디카르복시-1-(페닐아미드)-2-(4-(3-옥소-모르폴리노-4-일)-페닐아미드) 유도체 및 관련화합물 |
MXPA05013536A (es) | 2003-06-18 | 2006-03-09 | Merck Patent Gmbh | Derivados de etinilprolina. |
ES2223277B1 (es) | 2003-06-19 | 2006-03-01 | Fernando Bouffard Fita | Composicion anestesica para administracion topica. |
DE10358814A1 (de) * | 2003-12-16 | 2005-07-21 | Merck Patent Gmbh | Prolinylarylacetamide |
DE102004014945A1 (de) | 2004-03-26 | 2005-10-13 | Merck Patent Gmbh | Prolinylderivate |
US7453002B2 (en) * | 2004-06-15 | 2008-11-18 | Bristol-Myers Squibb Company | Five-membered heterocycles useful as serine protease inhibitors |
DE102004045796A1 (de) | 2004-09-22 | 2006-03-23 | Merck Patent Gmbh | Arzneimittel enthaltend Carbonylverbindungen sowie deren Verwendung |
EP1869010A1 (en) | 2005-04-11 | 2007-12-26 | Glaxo Group Limited | 3-sulfonylamino-pyrrolidine-2-one derivatives as factor xa inhibitors |
KR101083506B1 (ko) * | 2005-07-15 | 2011-11-16 | 에프. 호프만-라 로슈 아게 | 신규한 헤테로아릴 융합된 환형 아민 |
-
2007
- 2007-05-14 CA CA2653753A patent/CA2653753C/en not_active Expired - Fee Related
- 2007-05-14 DK DK07729083.1T patent/DK2051975T3/da active
- 2007-05-14 MY MYPI20084581A patent/MY146623A/en unknown
- 2007-05-14 EA EA200802210A patent/EA200802210A1/ru unknown
- 2007-05-14 NZ NZ573573A patent/NZ573573A/en not_active IP Right Cessation
- 2007-05-14 ES ES07729083T patent/ES2395538T3/es active Active
- 2007-05-14 WO PCT/EP2007/054631 patent/WO2007131982A2/de active Application Filing
- 2007-05-14 KR KR1020087027907A patent/KR101422456B1/ko not_active IP Right Cessation
- 2007-05-14 PE PE2007000580A patent/PE20080702A1/es not_active Application Discontinuation
- 2007-05-14 JP JP2009510435A patent/JP5263686B2/ja not_active Expired - Fee Related
- 2007-05-14 MX MX2008014499A patent/MX2008014499A/es active IP Right Grant
- 2007-05-14 EP EP07729083A patent/EP2051975B1/de active Active
- 2007-05-14 PL PL07729083T patent/PL2051975T3/pl unknown
- 2007-05-14 BR BRPI0711648-9A patent/BRPI0711648A2/pt not_active IP Right Cessation
- 2007-05-14 AU AU2007251614A patent/AU2007251614B2/en not_active Ceased
- 2007-05-15 CL CL2007001391A patent/CL2007001391A1/es unknown
- 2007-05-15 TW TW096117145A patent/TW200813047A/zh unknown
- 2007-05-15 UY UY30352A patent/UY30352A1/es not_active Application Discontinuation
- 2007-05-16 US US11/749,204 patent/US7807693B2/en active Active
- 2007-05-16 AR ARP070102101A patent/AR060945A1/es unknown
-
2008
- 2008-10-15 EC EC2008008824A patent/ECSP088824A/es unknown
- 2008-10-28 NO NO20084530A patent/NO20084530L/no not_active Application Discontinuation
- 2008-11-12 IL IL195245A patent/IL195245A/en not_active IP Right Cessation
-
2009
- 2009-11-19 HK HK09110801.9A patent/HK1131140A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AR060945A1 (es) | 2008-07-23 |
NZ573573A (en) | 2011-10-28 |
MY146623A (en) | 2012-09-14 |
ECSP088824A (es) | 2008-11-27 |
TW200813047A (en) | 2008-03-16 |
CA2653753A1 (en) | 2007-11-22 |
BRPI0711648A2 (pt) | 2011-11-29 |
PL2051975T3 (pl) | 2013-01-31 |
PE20080702A1 (es) | 2008-07-10 |
AU2007251614B2 (en) | 2013-01-17 |
UY30352A1 (es) | 2008-01-02 |
EA200802210A1 (ru) | 2009-06-30 |
WO2007131982A3 (de) | 2008-01-10 |
AU2007251614A1 (en) | 2007-11-22 |
IL195245A0 (en) | 2009-09-22 |
JP5263686B2 (ja) | 2013-08-14 |
EP2051975A2 (de) | 2009-04-29 |
WO2007131982A2 (de) | 2007-11-22 |
KR20090017523A (ko) | 2009-02-18 |
IL195245A (en) | 2012-09-24 |
ES2395538T3 (es) | 2013-02-13 |
HK1131140A1 (en) | 2010-01-15 |
KR101422456B1 (ko) | 2014-07-23 |
CL2007001391A1 (es) | 2008-01-18 |
EP2051975B1 (de) | 2012-09-12 |
JP2009537483A (ja) | 2009-10-29 |
CA2653753C (en) | 2013-09-24 |
MX2008014499A (es) | 2008-11-27 |
US20080139605A1 (en) | 2008-06-12 |
DK2051975T3 (da) | 2012-10-15 |
US7807693B2 (en) | 2010-10-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |