PL2051975T3 - Podstawione prolinamidy, ich wytwarzanie oraz ich zastosowanie jako środków leczniczych - Google Patents
Podstawione prolinamidy, ich wytwarzanie oraz ich zastosowanie jako środków leczniczychInfo
- Publication number
- PL2051975T3 PL2051975T3 PL07729083T PL07729083T PL2051975T3 PL 2051975 T3 PL2051975 T3 PL 2051975T3 PL 07729083 T PL07729083 T PL 07729083T PL 07729083 T PL07729083 T PL 07729083T PL 2051975 T3 PL2051975 T3 PL 2051975T3
- Authority
- PL
- Poland
- Prior art keywords
- drugs
- production
- prolinamides
- substituted
- substituted prolinamides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06113977 | 2006-05-16 | ||
EP07102566 | 2007-02-16 | ||
PCT/EP2007/054631 WO2007131982A2 (de) | 2006-05-16 | 2007-05-14 | Substituierte prolinamide, deren herstellung und deren verwendung als arzneimittel |
EP07729083A EP2051975B1 (de) | 2006-05-16 | 2007-05-14 | Substituierte prolinamide, deren herstellung und deren verwendung als arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2051975T3 true PL2051975T3 (pl) | 2013-01-31 |
Family
ID=38646563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL07729083T PL2051975T3 (pl) | 2006-05-16 | 2007-05-14 | Podstawione prolinamidy, ich wytwarzanie oraz ich zastosowanie jako środków leczniczych |
Country Status (24)
Country | Link |
---|---|
US (1) | US7807693B2 (pl) |
EP (1) | EP2051975B1 (pl) |
JP (1) | JP5263686B2 (pl) |
KR (1) | KR101422456B1 (pl) |
AR (1) | AR060945A1 (pl) |
AU (1) | AU2007251614B2 (pl) |
BR (1) | BRPI0711648A2 (pl) |
CA (1) | CA2653753C (pl) |
CL (1) | CL2007001391A1 (pl) |
DK (1) | DK2051975T3 (pl) |
EA (1) | EA200802210A1 (pl) |
EC (1) | ECSP088824A (pl) |
ES (1) | ES2395538T3 (pl) |
HK (1) | HK1131140A1 (pl) |
IL (1) | IL195245A (pl) |
MX (1) | MX2008014499A (pl) |
MY (1) | MY146623A (pl) |
NO (1) | NO20084530L (pl) |
NZ (1) | NZ573573A (pl) |
PE (1) | PE20080702A1 (pl) |
PL (1) | PL2051975T3 (pl) |
TW (1) | TW200813047A (pl) |
UY (1) | UY30352A1 (pl) |
WO (1) | WO2007131982A2 (pl) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1975165A1 (de) | 2007-03-27 | 2008-10-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Substituierte Pyrrolidinamide, deren Herstellung und deren Verwendung als Arzneimittel |
JP5524852B2 (ja) | 2007-11-15 | 2014-06-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換アミド、それらの製造及び医薬品としての使用 |
CA2719985A1 (en) * | 2008-03-31 | 2009-10-08 | Evotec Ag | Tetrahydronaphthyridines and aza derivatives thereof as histamine h3 receptor antagonists |
GB201209138D0 (en) * | 2012-05-24 | 2012-07-04 | Ono Pharmaceutical Co | Compounds |
WO2014127815A1 (en) | 2013-02-21 | 2014-08-28 | Boehringer Ingelheim International Gmbh | Dihydropteridinones i |
JP6337750B2 (ja) * | 2013-11-22 | 2018-06-06 | 小野薬品工業株式会社 | 化合物 |
PE20161372A1 (es) | 2014-02-03 | 2017-01-08 | Vitae Pharmaceuticals Inc | Inhibidores de dihidropirrolopiridina de ror-gamma |
EP3828173B1 (en) * | 2014-03-07 | 2022-08-31 | BioCryst Pharmaceuticals, Inc. | Substituted pyrazoles as human plasma kallikrein inhibitors |
UA118989C2 (uk) | 2014-10-14 | 2019-04-10 | Вітае Фармасьютікалс, Інк. | Дигідропіролопіридинові інгібітори ror-гамма |
US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
EP3078378B1 (en) | 2015-04-08 | 2020-06-24 | Vaiomer | Use of factor xa inhibitors for regulating glycemia |
EP3331876B1 (en) | 2015-08-05 | 2020-10-07 | Vitae Pharmaceuticals, LLC | Modulators of ror-gamma |
MA53943A (fr) | 2015-11-20 | 2021-08-25 | Vitae Pharmaceuticals Llc | Modulateurs de ror-gamma |
TW202220968A (zh) | 2016-01-29 | 2022-06-01 | 美商維它藥物有限責任公司 | ROR-γ調節劑 |
US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
CN111225914B (zh) | 2017-07-24 | 2022-10-11 | 生命医药有限责任公司 | RORγ的抑制剂 |
WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
CN114646701B (zh) * | 2022-03-01 | 2023-09-29 | 浙江国邦药业有限公司 | 一种l-脯氨酰胺中有关物质的hplc测试方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7030141B2 (en) | 2001-11-29 | 2006-04-18 | Christopher Franklin Bigge | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade |
JP3975254B2 (ja) * | 2002-07-25 | 2007-09-12 | 日野自動車株式会社 | チャイルドシート用アンカの取付構造 |
EP1720844B1 (de) | 2003-04-03 | 2009-04-29 | MERCK PATENT GmbH | Pyrrolidin-1,2-dicarbonsäure-1-(phenylamid)-2-(4-(3-oxo-morpholin-4-yl)-phenylamid) derivate und verwandte verbindungen als inhibitoren des koagulationsfaktors xa zur behandlung von thromboembolischen erkrankungen |
DE10329457A1 (de) | 2003-04-03 | 2005-01-20 | Merck Patent Gmbh | Ethinylprolinderivate |
KR20060023154A (ko) | 2003-06-18 | 2006-03-13 | 메르크 파텐트 게엠베하 | 혈전증 치료용 응고 인자 xa 및 viia의 저해제로서의피롤리딘-1,2-디카르복실산-1-[(4-에티닐-페닐)-아미드]-2-[(페닐)-아미드] 유도체 |
ES2223277B1 (es) | 2003-06-19 | 2006-03-01 | Fernando Bouffard Fita | Composicion anestesica para administracion topica. |
DE10358814A1 (de) | 2003-12-16 | 2005-07-21 | Merck Patent Gmbh | Prolinylarylacetamide |
DE102004014945A1 (de) * | 2004-03-26 | 2005-10-13 | Merck Patent Gmbh | Prolinylderivate |
US7453002B2 (en) * | 2004-06-15 | 2008-11-18 | Bristol-Myers Squibb Company | Five-membered heterocycles useful as serine protease inhibitors |
DE102004045796A1 (de) | 2004-09-22 | 2006-03-23 | Merck Patent Gmbh | Arzneimittel enthaltend Carbonylverbindungen sowie deren Verwendung |
EP1869010A1 (en) | 2005-04-11 | 2007-12-26 | Glaxo Group Limited | 3-sulfonylamino-pyrrolidine-2-one derivatives as factor xa inhibitors |
KR101083506B1 (ko) | 2005-07-15 | 2011-11-16 | 에프. 호프만-라 로슈 아게 | 신규한 헤테로아릴 융합된 환형 아민 |
-
2007
- 2007-05-14 EP EP07729083A patent/EP2051975B1/de active Active
- 2007-05-14 BR BRPI0711648-9A patent/BRPI0711648A2/pt not_active IP Right Cessation
- 2007-05-14 PL PL07729083T patent/PL2051975T3/pl unknown
- 2007-05-14 AU AU2007251614A patent/AU2007251614B2/en not_active Ceased
- 2007-05-14 DK DK07729083.1T patent/DK2051975T3/da active
- 2007-05-14 CA CA2653753A patent/CA2653753C/en not_active Expired - Fee Related
- 2007-05-14 WO PCT/EP2007/054631 patent/WO2007131982A2/de active Application Filing
- 2007-05-14 MX MX2008014499A patent/MX2008014499A/es active IP Right Grant
- 2007-05-14 KR KR1020087027907A patent/KR101422456B1/ko not_active IP Right Cessation
- 2007-05-14 NZ NZ573573A patent/NZ573573A/en not_active IP Right Cessation
- 2007-05-14 ES ES07729083T patent/ES2395538T3/es active Active
- 2007-05-14 PE PE2007000580A patent/PE20080702A1/es not_active Application Discontinuation
- 2007-05-14 MY MYPI20084581A patent/MY146623A/en unknown
- 2007-05-14 JP JP2009510435A patent/JP5263686B2/ja not_active Expired - Fee Related
- 2007-05-14 EA EA200802210A patent/EA200802210A1/ru unknown
- 2007-05-15 UY UY30352A patent/UY30352A1/es not_active Application Discontinuation
- 2007-05-15 CL CL2007001391A patent/CL2007001391A1/es unknown
- 2007-05-15 TW TW096117145A patent/TW200813047A/zh unknown
- 2007-05-16 US US11/749,204 patent/US7807693B2/en active Active
- 2007-05-16 AR ARP070102101A patent/AR060945A1/es unknown
-
2008
- 2008-10-15 EC EC2008008824A patent/ECSP088824A/es unknown
- 2008-10-28 NO NO20084530A patent/NO20084530L/no not_active Application Discontinuation
- 2008-11-12 IL IL195245A patent/IL195245A/en not_active IP Right Cessation
-
2009
- 2009-11-19 HK HK09110801.9A patent/HK1131140A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
UY30352A1 (es) | 2008-01-02 |
TW200813047A (en) | 2008-03-16 |
US20080139605A1 (en) | 2008-06-12 |
MX2008014499A (es) | 2008-11-27 |
WO2007131982A3 (de) | 2008-01-10 |
HK1131140A1 (en) | 2010-01-15 |
IL195245A0 (en) | 2009-09-22 |
JP5263686B2 (ja) | 2013-08-14 |
WO2007131982A2 (de) | 2007-11-22 |
KR20090017523A (ko) | 2009-02-18 |
CA2653753C (en) | 2013-09-24 |
AU2007251614B2 (en) | 2013-01-17 |
EA200802210A1 (ru) | 2009-06-30 |
IL195245A (en) | 2012-09-24 |
CA2653753A1 (en) | 2007-11-22 |
DK2051975T3 (da) | 2012-10-15 |
EP2051975A2 (de) | 2009-04-29 |
US7807693B2 (en) | 2010-10-05 |
ECSP088824A (es) | 2008-11-27 |
CL2007001391A1 (es) | 2008-01-18 |
PE20080702A1 (es) | 2008-07-10 |
AR060945A1 (es) | 2008-07-23 |
BRPI0711648A2 (pt) | 2011-11-29 |
NO20084530L (no) | 2008-12-12 |
EP2051975B1 (de) | 2012-09-12 |
ES2395538T3 (es) | 2013-02-13 |
MY146623A (en) | 2012-09-14 |
AU2007251614A1 (en) | 2007-11-22 |
NZ573573A (en) | 2011-10-28 |
JP2009537483A (ja) | 2009-10-29 |
KR101422456B1 (ko) | 2014-07-23 |
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