HK1121468A1 - Synthetic mecp2 sequence for protein substitution therapy - Google Patents

Synthetic mecp2 sequence for protein substitution therapy

Info

Publication number
HK1121468A1
HK1121468A1 HK09101479.9A HK09101479A HK1121468A1 HK 1121468 A1 HK1121468 A1 HK 1121468A1 HK 09101479 A HK09101479 A HK 09101479A HK 1121468 A1 HK1121468 A1 HK 1121468A1
Authority
HK
Hong Kong
Prior art keywords
protein
proteins
nucleic acid
relates
substitution therapy
Prior art date
Application number
HK09101479.9A
Other languages
English (en)
Inventor
Franco Antonio Laccone
Original Assignee
Univ Goettingen Georg August
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Goettingen Georg August filed Critical Univ Goettingen Georg August
Publication of HK1121468A1 publication Critical patent/HK1121468A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK09101479.9A 2006-04-07 2009-02-17 Synthetic mecp2 sequence for protein substitution therapy HK1121468A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2006/003203 WO2007115578A1 (fr) 2006-04-07 2006-04-07 Séquence mecp2 synthétique utilisée dans une thérapie de substitution de protéines

Publications (1)

Publication Number Publication Date
HK1121468A1 true HK1121468A1 (en) 2009-04-24

Family

ID=36589309

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09101479.9A HK1121468A1 (en) 2006-04-07 2009-02-17 Synthetic mecp2 sequence for protein substitution therapy

Country Status (16)

Country Link
US (1) US8226930B2 (fr)
EP (1) EP2010563B1 (fr)
JP (1) JP5102283B2 (fr)
CN (1) CN101415726B (fr)
AT (1) ATE500265T1 (fr)
AU (1) AU2006341726B2 (fr)
CA (1) CA2647125C (fr)
DE (1) DE602006020501D1 (fr)
DK (1) DK2010563T3 (fr)
ES (1) ES2362195T3 (fr)
HK (1) HK1121468A1 (fr)
HR (1) HRP20110386T1 (fr)
IL (1) IL194274A (fr)
PL (1) PL2010563T3 (fr)
SI (1) SI2010563T1 (fr)
WO (1) WO2007115578A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1398191B1 (it) * 2010-02-17 2013-02-14 Ist Superiore Sanita Uso di tossine che attivano le rho gtpasi per il trattamento e/o la prevenzione della sintomatologia associata alla sindrome di rett (rtt).
US9920317B2 (en) 2010-11-12 2018-03-20 The General Hospital Corporation Polycomb-associated non-coding RNAs
JP6336755B2 (ja) 2010-11-12 2018-06-06 ザ ジェネラル ホスピタル コーポレイション ポリコームに関連する非コードｒｎａ
CA2873797A1 (fr) 2012-05-16 2013-11-21 Rana Therapeutics Inc. Compositions et methodes pour moduler l'expression de utrn
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
AP2014008100A0 (en) 2012-05-16 2014-12-31 Gen Hospital Corp Compositions and methods for modulating hemoglobingene family expression
AU2013262699A1 (en) 2012-05-16 2015-01-22 Rana Therapeutics, Inc. Compositions and methods for modulating ATP2A2 expression
EA201492123A1 (ru) 2012-05-16 2015-10-30 Рана Терапьютикс, Инк. Композиции и способы для модулирования экспрессии семейства генов smn
CA2873779A1 (fr) 2012-05-16 2013-11-21 Rana Therapeutics Inc. Compositions et methodes pour moduler l'expression de mecp2
WO2014130408A1 (fr) * 2013-02-20 2014-08-28 The Research Foundation For The State University Of New York Régulateurs de l'activité de rab5
WO2016070060A1 (fr) 2014-10-30 2016-05-06 The General Hospital Corporation Procédés de modulation de la répression génique dépendant d'atrx
US10900036B2 (en) 2015-03-17 2021-01-26 The General Hospital Corporation RNA interactome of polycomb repressive complex 1 (PRC1)
TWI601821B (zh) * 2016-04-15 2017-10-11 中央研究院 治療神經發展性疾病
WO2018172794A1 (fr) * 2017-03-24 2018-09-27 The University Court Of The University Of Edinburgh Thérapie à base de mecp2
US11629342B2 (en) 2017-10-17 2023-04-18 President And Fellows Of Harvard College Cas9-based transcription modulation systems
KR102052097B1 (ko) * 2017-11-30 2019-12-05 한국과학기술연구원 Mecp2 단백질 또는 이를 암호화하는 폴리뉴클레오티드를 포함하는 퇴행성 뇌질환 예방 또는 치료용 조성물
KR20220003553A (ko) * 2019-04-24 2022-01-10 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 레트 증후군의 치료에 유용한 조성물
WO2023235648A1 (fr) * 2022-06-03 2023-12-07 The Regents Of The University Of California Administration nucléaire et répression transcriptionnelle à l'aide d'une protéine mecp2 de pénétration cellulaire

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7497000A (en) 1999-02-28 2000-11-14 Washington University Novel transduction molecules and methods for using same
US6709817B1 (en) * 1999-09-07 2004-03-23 Baylor College Of Medicine Method of screening Rett syndrome by detecting a mutation in MECP2
EP1385887A4 (fr) * 2001-04-20 2006-12-06 Univ Yonsei Seoul Represseurs de transcription du vih et procedes correspondants
JP5830213B2 (ja) * 2004-02-17 2015-12-09 ザ ホスピタル フォー シック チルドレン Ｍｅｃｐ２ｅ１遺伝子

Also Published As

Publication number Publication date
JP2009532045A (ja) 2009-09-10
CA2647125C (fr) 2015-02-03
CN101415726B (zh) 2013-07-31
HRP20110386T1 (hr) 2011-08-31
DK2010563T3 (da) 2011-05-23
WO2007115578A8 (fr) 2008-10-30
AU2006341726B2 (en) 2012-09-20
DE602006020501D1 (de) 2011-04-14
PL2010563T3 (pl) 2011-11-30
JP5102283B2 (ja) 2012-12-19
WO2007115578A1 (fr) 2007-10-18
IL194274A (en) 2011-07-31
ES2362195T3 (es) 2011-06-29
EP2010563B1 (fr) 2011-03-02
CA2647125A1 (fr) 2007-10-18
ATE500265T1 (de) 2011-03-15
EP2010563A1 (fr) 2009-01-07
AU2006341726A1 (en) 2007-10-18
CN101415726A (zh) 2009-04-22
US8226930B2 (en) 2012-07-24
SI2010563T1 (sl) 2011-07-29
US20090233856A1 (en) 2009-09-17

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180407