HK1120050A1 - High-level expression of recombinant antibody in a mammalian host cell - Google Patents

High-level expression of recombinant antibody in a mammalian host cell

Info

Publication number
HK1120050A1
HK1120050A1 HK08111996.3A HK08111996A HK1120050A1 HK 1120050 A1 HK1120050 A1 HK 1120050A1 HK 08111996 A HK08111996 A HK 08111996A HK 1120050 A1 HK1120050 A1 HK 1120050A1
Authority
HK
Hong Kong
Prior art keywords
host cell
mammalian host
recombinant antibody
level expression
expression
Prior art date
Application number
HK08111996.3A
Other languages
English (en)
Inventor
James Rance
Stephan Kalwy
Robert Young
Robert Gay
Original Assignee
Lonza Biologics Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37114510&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1120050(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0510277A external-priority patent/GB0510277D0/en
Priority claimed from GB0511353A external-priority patent/GB0511353D0/en
Priority claimed from GB0526372A external-priority patent/GB0526372D0/en
Application filed by Lonza Biologics Plc filed Critical Lonza Biologics Plc
Publication of HK1120050A1 publication Critical patent/HK1120050A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
HK08111996.3A 2005-05-20 2008-10-31 High-level expression of recombinant antibody in a mammalian host cell HK1120050A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0510277A GB0510277D0 (en) 2005-05-20 2005-05-20 High-level expression of recombinant antibody in a mammalian host cell
GB0511353A GB0511353D0 (en) 2005-06-03 2005-06-03 High-level expression of recombinant antibody in a mammalian host cell
GB0526372A GB0526372D0 (en) 2005-12-28 2005-12-28 High-level expression of recombinant antibody in a mammalian host cell
PCT/EP2006/004767 WO2006122822A2 (en) 2005-05-20 2006-05-19 High-level expression of recombinant antibody in a mammalian host cell

Publications (1)

Publication Number Publication Date
HK1120050A1 true HK1120050A1 (en) 2009-03-20

Family

ID=37114510

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08111996.3A HK1120050A1 (en) 2005-05-20 2008-10-31 High-level expression of recombinant antibody in a mammalian host cell

Country Status (10)

Country Link
US (1) US20090215165A1 (xx)
EP (1) EP1915394B1 (xx)
JP (1) JP4991705B2 (xx)
KR (1) KR101273829B1 (xx)
AU (1) AU2006249087B2 (xx)
CA (1) CA2606576A1 (xx)
ES (1) ES2864039T3 (xx)
HK (1) HK1120050A1 (xx)
IL (1) IL187100A (xx)
WO (1) WO2006122822A2 (xx)

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WO2010004004A1 (en) * 2008-07-09 2010-01-14 Profibrix Bv Recombinant fibrinogen
PT2448970E (pt) 2009-05-04 2014-10-20 Abbvie Res B V Anticorpos contra factor de crescimento nervoso (ngf) com estabilidade in vivo melhorada
JP5947727B2 (ja) 2010-01-20 2016-07-06 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 抗ｉｌｔ５抗体およびｉｌｔ５結合抗体断片による免疫調節
EP2525813B1 (en) 2010-01-20 2017-01-04 Merck Sharp & Dohme Corp. Anti-ilt5 antibodies and ilt5-binding antibody fragments
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US20130035472A1 (en) * 2010-03-17 2013-02-07 Anaptysbio, Inc. Method of producing transcripts using cryptic splice sites
SG193514A1 (en) 2011-04-01 2013-10-30 Immunogen Inc Methods for increasing efficacy of folr1 cancer therapy
KR102617499B1 (ko) 2012-08-31 2023-12-22 이뮤노젠 아이엔씨 엽산 수용체 1의 검출을 위한 진단성 검정 및 키트
CN105814079B (zh) 2013-08-30 2021-02-09 伊缪诺金公司 用于检测叶酸受体1的抗体和测定
WO2015120180A1 (en) * 2014-02-05 2015-08-13 The University Of Chicago Chimeric antigen receptors recognizing cancer-specific tn glycopeptide variants
US10544209B2 (en) 2014-10-15 2020-01-28 Alexion Pharmaceuticals, Inc. Methods of replicating a large scale eculizumab production cell culture
US20160108357A1 (en) * 2014-10-15 2016-04-21 Alexion Pharmaceuticals, Inc. Methods of culturing a cell
WO2016156537A1 (en) * 2015-03-31 2016-10-06 Novimmune Sa Method for optimizing the assembly and production of hetero-multimeric protein complexes
CN104946687B (zh) * 2015-06-09 2018-09-14 北京东方百泰生物科技有限公司 哺乳动物双基因高效筛选表达载体及其构建方法
CN108601828B (zh) 2015-09-17 2023-04-28 伊缪诺金公司 包含抗folr1免疫缀合物的治疗组合

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Also Published As

Publication number Publication date
WO2006122822A3 (en) 2007-04-12
AU2006249087B2 (en) 2012-05-17
IL187100A (en) 2013-07-31
JP2008539773A (ja) 2008-11-20
KR20080016871A (ko) 2008-02-22
KR101273829B1 (ko) 2013-06-11
EP1915394B1 (en) 2021-01-27
JP4991705B2 (ja) 2012-08-01
IL187100A0 (en) 2008-02-09
EP1915394A2 (en) 2008-04-30
US20090215165A1 (en) 2009-08-27
CA2606576A1 (en) 2006-11-23
AU2006249087A1 (en) 2006-11-23
ES2864039T3 (es) 2021-10-13
WO2006122822A2 (en) 2006-11-23

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