HK1112898A1 - - Google Patents

Info

Publication number
HK1112898A1
HK1112898A1 HK08101944.7A HK08101944A HK1112898A1 HK 1112898 A1 HK1112898 A1 HK 1112898A1 HK 08101944 A HK08101944 A HK 08101944A HK 1112898 A1 HK1112898 A1 HK 1112898A1
Authority
HK
Hong Kong
Prior art keywords
dihydrate
fluoroisoquinolin
sulfonyl
methyl
present
Prior art date
Application number
HK08101944.7A
Other languages
English (en)
Inventor
Takeshi Ohshima
Hiroyoshi Hidaka
Masami Shiratsuchi
Kazuhiro Onogi
Toshiaki Oda
Original Assignee
Kowa Co
Western Therapeutics Inst Inc D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36498130&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1112898(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kowa Co, Western Therapeutics Inst Inc D filed Critical Kowa Co
Publication of HK1112898A1 publication Critical patent/HK1112898A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK08101944.7A 2004-11-29 2008-02-22 HK1112898A1 (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004344271 2004-11-29
PCT/JP2005/021844 WO2006057397A1 (ja) 2004-11-29 2005-11-29 （ｓ）－（－）－１－（４－フルオロイソキノリン－５－イル）スルホニル－２－メチル－１，４－ホモピペラジン塩酸塩・二水和物

Publications (1)

Publication Number Publication Date
HK1112898A1 true HK1112898A1 (xx) 2008-09-19

Family

ID=36498130

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08101944.7A HK1112898A1 (xx) 2004-11-29 2008-02-22

Country Status (24)

Country Link
US (1) US7858615B2 (xx)
EP (1) EP1818329B1 (xx)
JP (1) JP4016060B2 (xx)
KR (1) KR101253369B1 (xx)
CN (1) CN101068806B (xx)
AT (1) ATE465159T1 (xx)
AU (1) AU2005308060B2 (xx)
BR (1) BRPI0517909B8 (xx)
CA (1) CA2589237C (xx)
CY (1) CY1112406T1 (xx)
DE (1) DE602005020835D1 (xx)
DK (1) DK1818329T3 (xx)
EA (1) EA011283B1 (xx)
ES (1) ES2345562T3 (xx)
HK (1) HK1112898A1 (xx)
MX (1) MX2007006322A (xx)
MY (1) MY139797A (xx)
NO (1) NO339021B1 (xx)
NZ (1) NZ555560A (xx)
PL (1) PL1818329T3 (xx)
PT (1) PT1818329E (xx)
TW (1) TWI354670B (xx)
WO (1) WO2006057397A1 (xx)
ZA (1) ZA200704201B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006290827A (ja) * 2005-04-13 2006-10-26 Kowa Co 緑内障予防又は治療剤
BRPI0614974A2 (pt) * 2005-08-30 2010-12-14 Asahi Kasei Pharma Corp composto, medicamento, inibidor da fosforilaÇço da cadeia leve regulatària da miosina, inibidor da via rho/rho quinase, e, mÉtodo para tratamento terapÊutico e/ou profilÁtico de glaucoma
US8415372B2 (en) * 2007-02-27 2013-04-09 Asahi Kasei Pharma Corporation Sulfonamide compound
EP2130828A4 (en) * 2007-02-28 2010-12-29 Asahi Kasei Pharma Corp sulfonamide
JP5234825B2 (ja) 2007-07-02 2013-07-10 旭化成ファーマ株式会社 スルホンアミド化合物及びその結晶
UA102128C2 (xx) * 2008-12-05 2013-06-10 Х. Луннбек А/С Налмефену гідрохлориду дигідрат$налмефена гидрохлорида дигидрат
CN103951624B (zh) 2010-08-26 2019-04-16 兴和株式会社 1,4-二氮杂环庚烷衍生物或其盐的制造方法
US20160339018A1 (en) * 2013-04-24 2016-11-24 Kyushu University, National University Corporation Therapeutic agent for ocular fundus disease
WO2016047721A1 (ja) * 2014-09-25 2016-03-31 興和株式会社 医薬製剤
WO2016111688A1 (en) * 2015-01-08 2016-07-14 Hewlett-Packard Development Company, L.P. Mobile printers
CN107216311B (zh) * 2016-03-21 2019-09-03 山东诚创医药技术开发有限公司 (s)-4-[(4-氟代异喹啉-5-基)磺酰基]-3-甲基-1,4-二氮杂环庚烷盐酸盐的精制方法
CN106496189A (zh) * 2016-10-10 2017-03-15 江苏礼华生物技术有限公司 盐酸Ripasudil晶型
CN107164328A (zh) * 2017-06-30 2017-09-15 太仓卡斯特姆新材料有限公司 一种高稳定性mcf‑7乳腺癌细胞的复苏方法
PT3901141T (pt) 2018-12-17 2024-03-04 D Western Therapeutics Inst Inc Nova forma de isoquinolinossulfonamida
CN113906017B (zh) * 2019-06-21 2024-07-02 广州润尔眼科生物科技有限公司 作为rock蛋白激酶抑制剂的异喹啉酮的衍生物及其应用
CN114644618A (zh) 2020-12-21 2022-06-21 广州润尔眼科生物科技有限公司 一种作为rock蛋白激酶抑制剂的异喹啉酮型化合物的盐型及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3734531B2 (ja) * 1995-06-29 2006-01-11 旭化成ファーマ株式会社 １−（５−イソキノリンスルホニル）ホモピペラジン塩酸塩３水和物
CN1080721C (zh) * 1995-07-03 2002-03-13 旭化成株式会社 1－(5－异喹啉磺酰基)高哌嗪盐酸盐水合物
KR19990082174A (ko) * 1996-02-02 1999-11-25 니뽄 신야쿠 가부시키가이샤 이소퀴놀린 유도체 및 의약
AU9646198A (en) * 1997-10-22 1999-05-10 Nippon Shinyaku Co. Ltd. Isoquinoline derivative and drug

Also Published As

Publication number Publication date
AU2005308060A1 (en) 2006-06-01
WO2006057397A1 (ja) 2006-06-01
CN101068806A (zh) 2007-11-07
PT1818329E (pt) 2010-06-22
CA2589237C (en) 2013-05-14
NO339021B1 (no) 2016-11-07
EP1818329A4 (en) 2009-08-05
DE602005020835D1 (de) 2010-06-02
MX2007006322A (es) 2007-06-19
AU2005308060B2 (en) 2011-02-17
EA200701156A1 (ru) 2007-10-26
US7858615B2 (en) 2010-12-28
KR20070084127A (ko) 2007-08-24
KR101253369B1 (ko) 2013-04-11
PL1818329T3 (pl) 2010-10-29
CN101068806B (zh) 2012-02-01
NZ555560A (en) 2008-10-31
JPWO2006057397A1 (ja) 2008-06-05
BRPI0517909B8 (pt) 2021-05-25
ES2345562T3 (es) 2010-09-27
MY139797A (en) 2009-10-30
TWI354670B (en) 2011-12-21
EA011283B1 (ru) 2009-02-27
EP1818329B1 (en) 2010-04-21
CY1112406T1 (el) 2015-12-09
ZA200704201B (en) 2008-09-25
DK1818329T3 (da) 2010-07-19
JP4016060B2 (ja) 2007-12-05
TW200630359A (en) 2006-09-01
ATE465159T1 (de) 2010-05-15
US20080021018A1 (en) 2008-01-24
CA2589237A1 (en) 2006-06-01
NO20072382L (no) 2007-08-23
BRPI0517909B1 (pt) 2018-11-21
EP1818329A1 (en) 2007-08-15
BRPI0517909A (pt) 2008-10-21

Similar Documents

Publication Publication Date Title
HK1112898A1 (xx)
MX2007003108A (es) Compuestos imidazo-3-il-amina sustituidos y biciclicos.
WO2004037181A3 (en) Glycinenitrile-based inhibitors of dipeptidyl peptidase iv and methods
EP1794120A4 (en) peptidase
GEP20084361B (en) Piperidinylcarbonyl-pyrro-lidines and their use as melanocortin agonists
TW200505919A (en) DPP-IV inhibitors
TNSN05244A1 (en) Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter
EA200801607A1 (ru) Производные бензимидазолонкарбоновой кислоты
MX2007006630A (es) Metodo para preparar n-fenilpirazol-1-carboxamidas.
TW200626610A (en) Analogs of 17-hydroxywortmannin as PI3K inhibitors
WO2005075425A3 (en) Substituted bisarylurea derivatives as kinase inhibitors
MY142799A (en) Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
SI1585739T1 (sl) Substituirani arilciklopropilacetamidi kot aktivatorji glukokinaze
DK1756052T3 (da) Forbedret fremgangsmåde til at fremstille 3-hydroxy-4-hydroxymethyl-pyrrolidin-forbindelser
PL1758852T3 (pl) Podstawione związki cyklopentenu
GB0412769D0 (en) Organic compounds
TW200738621A (en) Chemical process
TNSN04250A1 (en) Diphenyl azetidinones substituted by acidic groups, method for their production, medicaments containing said compounds and use thereof.
RS20060297A (xx) Premešteni pentanoli, postupak za njihovu proizvodnju i njihova upotreba kao anti-inflamatornih sredstava
MXPA05010020A (es) Derivados de oxamida.
GB0212410D0 (en) Organic compounds
GB0417063D0 (en) Process for the preparation of optically-active compounds
GB0314299D0 (en) Chemical compounds
UA93030C2 (ru) Способ получения клопидогрела (варианты) и промежуточные соединения
TW200420552A (en) Dihydro-furan-2-one derivatives, their intermediates and methods of manufacture

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20221126