HK1108468A1 - Optoelectronic detection system - Google Patents

Optoelectronic detection system

Info

Publication number
HK1108468A1
HK1108468A1 HK08102374.4A HK08102374A HK1108468A1 HK 1108468 A1 HK1108468 A1 HK 1108468A1 HK 08102374 A HK08102374 A HK 08102374A HK 1108468 A1 HK1108468 A1 HK 1108468A1
Authority
HK
Hong Kong
Prior art keywords
detection
target particle
detection system
sample
detecting
Prior art date
Application number
HK08102374.4A
Other languages
English (en)
Inventor
Eric D Schwoebel
James D Harper
Martha S Petrovick
Frances E Nargi
Todd H Rider
Kristine E Hogan
Richard H Mathews
Joseph Lacirignola
Mark Hennessy
Trina R Vian
Rose M Joseph
Raymond Uttaro
Shaun Berry
Mark A Hollis
Bernadette Johnson
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of HK1108468A1 publication Critical patent/HK1108468A1/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • G01N33/5304Reaction vessels, e.g. agglutination plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/34Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C12M1/3446Photometry, spectroscopy, laser technology
    • C12M1/3461Bio- or chemi-luminescence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/34Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C12M1/3446Photometry, spectroscopy, laser technology
    • C12M1/3476Fluorescence spectroscopy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Sustainable Development (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Photo Coupler, Interrupter, Optical-To-Optical Conversion Devices (AREA)
HK08102374.4A 2004-12-01 2008-03-03 Optoelectronic detection system HK1108468A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/001,583 US7422860B2 (en) 2001-02-07 2004-12-01 Optoelectronic detection system
PCT/US2005/043343 WO2007046825A2 (en) 2004-12-01 2005-11-30 Optoelectronic detection system

Publications (1)

Publication Number Publication Date
HK1108468A1 true HK1108468A1 (en) 2008-05-09

Family

ID=37903963

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08102374.4A HK1108468A1 (en) 2004-12-01 2008-03-03 Optoelectronic detection system

Country Status (10)

Country Link
US (4) US7422860B2 (ja)
EP (1) EP1831404B1 (ja)
JP (1) JP5523673B2 (ja)
CN (1) CN101111605B (ja)
AT (1) ATE466108T1 (ja)
AU (1) AU2005337484B2 (ja)
CA (1) CA2588787A1 (ja)
DE (1) DE602005020978D1 (ja)
HK (1) HK1108468A1 (ja)
WO (1) WO2007046825A2 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
JP4295511B2 (ja) * 2001-02-07 2009-07-15 マサチューセッツ・インスティテュート・オブ・テクノロジー 光電子による検出システム
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
WO2008048300A2 (en) * 2005-11-30 2008-04-24 Massachusetts Institute Of Technology Pathogen detection biosensor
AT500427B1 (de) * 2002-05-29 2009-02-15 Anagnostics Bioanalysis Gmbh Vorrichtung zur analyse von bestandteilen einer probe
AT502549B1 (de) * 2005-10-07 2007-06-15 Anagnostics Bioanalysis Gmbh Vorrichtung zur analyse von flüssigen proben
US20090270269A1 (en) * 2008-04-28 2009-10-29 Ashok Kumar Nano-scale fluoro-biosensors exhibiting a low false alarm rate for rapid detection of biological contaminants
JP5571294B2 (ja) * 2008-05-14 2014-08-13 旭川ポートリー株式会社 培養装置および培養方法
AU2009327189B2 (en) * 2008-12-16 2012-09-06 Novartis Ag Yeast display systems
US8647829B2 (en) * 2009-02-20 2014-02-11 General Electric Company Switchable affinity binders
US8955368B2 (en) 2011-09-21 2015-02-17 Massachusetts Institute Of Technology Apparatus and method for aerosol collection and fluid analysis
US9023640B2 (en) * 2011-12-13 2015-05-05 Fundamental Solutions Corporation Device for rapid detection of infectious agents
CN105190310B (zh) 2013-03-11 2018-04-10 托莱多大学 用于体内原位和/或实时靶定分析物的生物感应器装置及其制造与使用方法
JP6161072B2 (ja) * 2013-12-26 2017-07-12 国立研究開発法人産業技術総合研究所 多チャンネル式化学発光計測システム
GB201600315D0 (en) * 2015-08-13 2016-02-24 Gen Electric Heatseal sampling
CN108305912B (zh) * 2017-01-11 2024-03-26 中国科学院上海微系统与信息技术研究所 具有波长选择性的石墨烯仿生光探测器及其制备方法
KR102016131B1 (ko) * 2017-04-17 2019-10-21 (주)레보스케치 원심력을 이용한 디지털 pcr 장치 및 방법
CN111534419A (zh) * 2020-03-23 2020-08-14 湖南大学 呼吸道微生物快速检测系统及方法
CN114544726B (zh) * 2022-02-21 2024-05-03 浙江理工大学 一种丝素蛋白检测用pn型纤维状光电探测器的制备方法

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880592A (en) 1973-07-05 1975-04-29 Instrumentation Labor Inc Blood analysis system including a plasma separator
US4493895A (en) 1981-09-24 1985-01-15 Occidental Chemical Corporation Microbial degradation of obnoxious organic wastes into innocuous materials
US4499052A (en) 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4632761A (en) 1983-08-15 1986-12-30 W. R. Grace & Co. Centrifugal microconcentrator and methods for its use
US4675287A (en) 1984-07-26 1987-06-23 Scripps Clinic And Research Foundation Monoclonal antibody directed to human ganglioside GD2
JPH0823558B2 (ja) 1984-11-27 1996-03-06 オ−ジエニクス リミテツド 検定装置
US5422266A (en) 1984-12-31 1995-06-06 University Of Georgia Research Foundation, Inc. Recombinant DNA vectors capable of expressing apoaequorin
NZ214563A (en) 1984-12-31 1991-05-28 Univ Georgia Production of apoaeqorin using recombinant dna
WO1986007463A1 (en) 1985-06-03 1986-12-18 American National Red Cross Microtiter - surface - flocculation assay for antigen or antibody screening
AU596987B2 (en) 1985-08-30 1990-05-24 Tosoh Corporation Automated immunoassay analyser
US4678607A (en) 1986-07-25 1987-07-07 E. I. Du Pont De Nemours And Company Ethylene copolymers with enhanced fire resistant properties
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5698450A (en) 1986-10-14 1997-12-16 Ringrose; Anthony Method for measuring antigens or antibodies in biological fluids
JPS6435374A (en) 1987-07-31 1989-02-06 Fujirebio Kk Method and apparatus for fully automatic agglutination immune analysis
DE3889261D1 (de) 1987-07-31 1994-06-01 Fujirebio Kk Gerät zur automatischen immunologischen Analyse.
JP2592623B2 (ja) 1987-11-18 1997-03-19 チッソ株式会社 アポエクオリンの製造法
JPH01250065A (ja) * 1988-03-30 1989-10-05 Matsushita Electric Ind Co Ltd 有機ニトロ化合物の検知・分析方法
US5017342A (en) 1988-06-01 1991-05-21 Ortho Diagnostic Systems Inc. Device for immunoassay determinations
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP0372352B1 (en) 1988-12-06 1995-06-07 Chisso Corporation Aequorin fused with a protein having a specific-binding activity, its preparation, its purification and detection method by its use
JPH02253162A (ja) 1989-03-27 1990-10-11 Chisso Corp 特異的結合能を有する物質と結合したエクオリンを用いる検出法
ES2070942T3 (es) 1989-04-07 1995-06-16 Abbott Lab Metodo y dispositivo para la separacion de plasma o suero de sangre completa.
JPH03153700A (ja) 1989-11-09 1991-07-01 Chisso Corp 物理吸着法により担体に固定化されたエクオリン活性を示す蛋白質
US5292658A (en) 1989-12-29 1994-03-08 University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center Cloning and expressions of Renilla luciferase
US5846708A (en) 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
DE69330417T2 (de) 1992-02-10 2002-05-29 Baxter Int Verfahren zur testung von blutkonserven auf virale verunreinigung
JPH06160387A (ja) * 1992-11-20 1994-06-07 Mitsubishi Kasei Corp 抗原・抗体反応の測定方法
US5360728A (en) 1992-12-01 1994-11-01 Woods Hole Oceanographic Institution (W.H.O.I.) Modified apoaequorin having increased bioluminescent activity
DE69434867T2 (de) 1993-02-01 2007-05-16 Thermo Electron Oy Gerät zur Bestimmung eines Analyten in einer Probe
US5714666A (en) 1993-02-09 1998-02-03 Children's Hospital Of Philadelphia Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells
US5552064A (en) 1993-02-26 1996-09-03 Ortho Diagnostic Systems, Inc. Column agglutination assay and device using biphasic centrifugation
US5578269A (en) 1993-06-11 1996-11-26 Ortho Diagnostic Systems Inc. Automated blood analysis system with an integral centrifuge
EP0720650B1 (en) 1993-09-20 2004-12-01 Novartis AG Human metabotropic glutamate receptor subtype hmglur7 and related dna compounds
EP0746778A1 (en) 1994-02-25 1996-12-11 Massachusetts Institute Of Technology Methods and apparatus for detecting and imaging particles
JP3153700B2 (ja) 1994-03-03 2001-04-09 株式会社アイ・エイチ・アイ・エアロスペース ガスタービンエンジンの点火装置
US6143510A (en) 1994-07-29 2000-11-07 Iatron Laboratories Inc. Measuring method using whole blood sample
US5744320A (en) 1995-06-07 1998-04-28 Promega Corporation Quenching reagents and assays for enzyme-mediated luminescence
CA2181109A1 (en) 1995-07-18 1997-01-19 Nobuko Imajo Polypeptide and process for measuring living body components using the same
US5585266A (en) 1995-10-05 1996-12-17 Plitt; Cheryl A. Immobilized cell bioreactor
US5702884A (en) 1996-03-12 1997-12-30 Johnson & Johnson Clinical Diagnostics, Inc. Whole blood sample preparation for polymerase chain reaction using ammonium chloride and a carboxylic acid or metal carboxylate for selective red blood cell lysis
US5701012A (en) 1996-03-19 1997-12-23 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Fluorescent biological particle detection system
US6103479A (en) 1996-05-30 2000-08-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
ATE332572T1 (de) 1996-06-19 2006-07-15 Matsushita Electric Ind Co Ltd Photoelektronisches material, dieses verwendende vorrichtungen und herstellungsverfahren
DE19631855C2 (de) 1996-08-07 1998-10-15 Komanns Aribert Verfahren und Vorrichtung zur Erfassung von Oberflächenantigenen oder Strukturmerkmalen von Zellen, Partikeln oder Makromolekülen
US20030104390A1 (en) 1996-11-11 2003-06-05 Laurent Etienne Use of biosensors to diagnose plant diseases
US5958703A (en) 1996-12-03 1999-09-28 Glaxo Group Limited Use of modified tethers in screening compound libraries
US5932795A (en) 1997-01-22 1999-08-03 President And Fellows Of Harvard College Methods and apparatus for continuous ambient particulate mass monitoring
US5985214A (en) 1997-05-16 1999-11-16 Aurora Biosciences Corporation Systems and methods for rapidly identifying useful chemicals in liquid samples
DE19730497C2 (de) 1997-07-16 2000-02-10 Heermann Klaus Hinrich Verfahren zum Waschen, zur Separierung und Konzentrierung von Biomolekülen unter Verwendung eines Magnetstifts
US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
US6087114A (en) 1997-12-09 2000-07-11 Massachusetts Institute Of Technology Optoelectronic sensor
US6007778A (en) 1998-03-20 1999-12-28 Wisconsin Alumni Research Foundation Hermetic reaction tube for spectroscopy
US6261848B1 (en) 1998-05-08 2001-07-17 The Johns Hopkins University Miniature immuno-optical rapid analyte sensor platform
WO2000002045A2 (en) 1998-07-06 2000-01-13 Euroscreen S.A. Bioluminescent assay for agonists or antagonists of a calcium-coupled receptor
FR2790093A1 (fr) 1999-02-24 2000-08-25 Scibiex Sarl Procede d'analyse immunologique par reaction d'adherence
GR1003489B (el) 1999-11-19 2000-11-30 Μεθοδος προσδιορισμου βιολογικων και χημικων παραγοντων μεσω της μετρησης των μεταβολων των ηλεκτρικων ιδιοτητων ακινητοποιημενων κυτταρων ή συστατικων αυτων (βιοηλεκτρικη μεθοδος αναγνωρισης)
WO2001087486A2 (en) 2000-05-15 2001-11-22 Tecan Trading Ag Microfluidics devices and methods for performing cell based assays
US7144729B2 (en) 2000-09-01 2006-12-05 Dfb Pharmaceuticals, Inc. Methods and compositions for tissue regeneration
WO2008048300A2 (en) 2005-11-30 2008-04-24 Massachusetts Institute Of Technology Pathogen detection biosensor
JP4295511B2 (ja) 2001-02-07 2009-07-15 マサチューセッツ・インスティテュート・オブ・テクノロジー 光電子による検出システム
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
US6672947B2 (en) 2001-03-13 2004-01-06 Nptest, Llc Method for global die thinning and polishing of flip-chip packaged integrated circuits
JP2004532108A (ja) 2001-04-23 2004-10-21 マサチューセッツ インスチテュート オブ テクノロジー 抗菌性ポリマー表面
CN100354430C (zh) 2001-09-06 2007-12-12 基因描绘系统有限公司 一种检测样品中靶细胞或病毒的方法
US20040058327A1 (en) 2002-09-20 2004-03-25 Pan Jeffrey Y Method for using a blank matrix in a continuous format high throughput screening process
CN1323296C (zh) 2004-07-05 2007-06-27 江苏省肿瘤医院 硅烷交联壳聚糖膜基的流动注射化学发光免疫检测池及制备方法

Also Published As

Publication number Publication date
US20150050723A1 (en) 2015-02-19
US7422860B2 (en) 2008-09-09
AU2005337484A1 (en) 2007-04-26
US9494579B2 (en) 2016-11-15
US20080166705A1 (en) 2008-07-10
AU2005337484B2 (en) 2010-04-29
JP5523673B2 (ja) 2014-06-18
US8835127B2 (en) 2014-09-16
CN101111605B (zh) 2013-04-03
US20120135404A1 (en) 2012-05-31
JP2008522195A (ja) 2008-06-26
DE602005020978D1 (de) 2010-06-10
ATE466108T1 (de) 2010-05-15
US20100041031A1 (en) 2010-02-18
WO2007046825A3 (en) 2007-07-26
CN101111605A (zh) 2008-01-23
WO2007046825A9 (en) 2007-06-21
EP1831404B1 (en) 2010-04-28
WO2007046825A2 (en) 2007-04-26
EP1831404A2 (en) 2007-09-12
CA2588787A1 (en) 2007-04-26
US8067184B2 (en) 2011-11-29

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20151130