JPS6435374A - Method and apparatus for fully automatic agglutination immune analysis - Google Patents
Method and apparatus for fully automatic agglutination immune analysisInfo
- Publication number
- JPS6435374A JPS6435374A JP19021487A JP19021487A JPS6435374A JP S6435374 A JPS6435374 A JP S6435374A JP 19021487 A JP19021487 A JP 19021487A JP 19021487 A JP19021487 A JP 19021487A JP S6435374 A JPS6435374 A JP S6435374A
- Authority
- JP
- Japan
- Prior art keywords
- image
- agglutination
- obtd
- coefft
- fluctuation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
PURPOSE:To fully automate an agglutination immune analysis by providing a detector which takes in the agglutination image of the agglutination immune reaction and a decision device which makes image processing of the image taken therein. CONSTITUTION:The agglutination image of a well 8 on a microplate 7 is picked up by a TV camera 12 under adequate illumination and is stored as a video image into an image memory 13. The stored video image is received in a decision device part. The differential image is first obtd. by an image processor 14 at this time, and further, the contour and area of the agglutination image are determined. A standard deviation S with picture elements having >=0 brightness level is obtd. by a standard deviation calculator 15; furthermore, the coefft. CV of fluctuation is obtd. by a coefft. of fluctuation calculator 16. The coefft. CV of fluctuation and the area obtd. by the image processing 14 are inputted to a plotter 17 and is compared with the reference value stored in a memory 21 by a comparator 22, by which the decision of the result is executed.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19021487A JPS6435374A (en) | 1987-07-31 | 1987-07-31 | Method and apparatus for fully automatic agglutination immune analysis |
DE3889261T DE3889261D1 (en) | 1987-07-31 | 1988-07-29 | Automatic immunological analysis device. |
EP88112355A EP0301583B1 (en) | 1987-07-31 | 1988-07-29 | Automatic immunological analysing apparatus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19021487A JPS6435374A (en) | 1987-07-31 | 1987-07-31 | Method and apparatus for fully automatic agglutination immune analysis |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6435374A true JPS6435374A (en) | 1989-02-06 |
Family
ID=16254366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP19021487A Pending JPS6435374A (en) | 1987-07-31 | 1987-07-31 | Method and apparatus for fully automatic agglutination immune analysis |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6435374A (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05297001A (en) * | 1992-04-15 | 1993-11-12 | Fujirebio Inc | Method and device for automatic immunity measurement using magnetic particle |
JP2000121511A (en) * | 1998-10-13 | 2000-04-28 | Hitachi Koki Co Ltd | Automatic separation and extraction device and its control method |
US7670846B2 (en) | 2002-06-29 | 2010-03-02 | Roche Diagnostics Operations, Inc. | Automatic differentiation of a sample solution and a control solution |
JP2010175355A (en) * | 2009-01-29 | 2010-08-12 | Hitachi High-Technologies Corp | Automatic analyzer |
US7947509B2 (en) | 2001-02-07 | 2011-05-24 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US8067184B2 (en) | 2001-02-07 | 2011-11-29 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US8216797B2 (en) | 2001-02-07 | 2012-07-10 | Massachusetts Institute Of Technology | Pathogen detection biosensor |
US8722347B2 (en) | 1997-12-09 | 2014-05-13 | Massachusetts Institute Of Technology | Optoelectronic sensor |
-
1987
- 1987-07-31 JP JP19021487A patent/JPS6435374A/en active Pending
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05297001A (en) * | 1992-04-15 | 1993-11-12 | Fujirebio Inc | Method and device for automatic immunity measurement using magnetic particle |
US8722347B2 (en) | 1997-12-09 | 2014-05-13 | Massachusetts Institute Of Technology | Optoelectronic sensor |
JP2000121511A (en) * | 1998-10-13 | 2000-04-28 | Hitachi Koki Co Ltd | Automatic separation and extraction device and its control method |
US7947509B2 (en) | 2001-02-07 | 2011-05-24 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US8067184B2 (en) | 2001-02-07 | 2011-11-29 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US8216797B2 (en) | 2001-02-07 | 2012-07-10 | Massachusetts Institute Of Technology | Pathogen detection biosensor |
US8835127B2 (en) | 2001-02-07 | 2014-09-16 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US9005989B2 (en) | 2001-02-07 | 2015-04-14 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US9291549B2 (en) | 2001-02-07 | 2016-03-22 | Massachusetts Institute Of Technology | Pathogen detection biosensor |
US9494579B2 (en) | 2001-02-07 | 2016-11-15 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US7670846B2 (en) | 2002-06-29 | 2010-03-02 | Roche Diagnostics Operations, Inc. | Automatic differentiation of a sample solution and a control solution |
JP2010175355A (en) * | 2009-01-29 | 2010-08-12 | Hitachi High-Technologies Corp | Automatic analyzer |
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