HK1107353A1 - Fluoridation process for the synthesis of 2-[18f] fluoro-2-deoxy-d-glucose - Google Patents
Fluoridation process for the synthesis of 2-[18f] fluoro-2-deoxy-d-glucoseInfo
- Publication number
- HK1107353A1 HK1107353A1 HK08101069.6A HK08101069A HK1107353A1 HK 1107353 A1 HK1107353 A1 HK 1107353A1 HK 08101069 A HK08101069 A HK 08101069A HK 1107353 A1 HK1107353 A1 HK 1107353A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- deoxy
- fluoro
- glucose
- synthesis
- fluoridation process
- Prior art date
Links
- 238000004334 fluoridation Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- AOYNUTHNTBLRMT-MXWOLSILSA-N 2-Deoxy-2(F-18)fluoro-2-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H]([18F])C=O AOYNUTHNTBLRMT-MXWOLSILSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0425501.4A GB0425501D0 (en) | 2004-11-19 | 2004-11-19 | Fluoridation process |
| PCT/GB2005/004451 WO2006054098A2 (en) | 2004-11-19 | 2005-11-18 | Fluoridation process for the synthesis of 2- [18f] fluoro-2-deoxy-d-glucose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1107353A1 true HK1107353A1 (en) | 2008-04-03 |
Family
ID=33548541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK08101069.6A HK1107353A1 (en) | 2004-11-19 | 2008-01-28 | Fluoridation process for the synthesis of 2-[18f] fluoro-2-deoxy-d-glucose |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20090076259A1 (no) |
| EP (1) | EP1817320B1 (no) |
| JP (1) | JP5318416B2 (no) |
| KR (1) | KR101267122B1 (no) |
| CN (1) | CN101061130B (no) |
| AT (1) | ATE472552T1 (no) |
| AU (1) | AU2005305624B2 (no) |
| BR (1) | BRPI0518316A2 (no) |
| CA (1) | CA2584649C (no) |
| DE (1) | DE602005022099D1 (no) |
| ES (1) | ES2347165T3 (no) |
| GB (1) | GB0425501D0 (no) |
| HK (1) | HK1107353A1 (no) |
| IL (1) | IL182740A0 (no) |
| MX (1) | MX2007006052A (no) |
| NO (1) | NO20073037L (no) |
| NZ (1) | NZ554613A (no) |
| PL (1) | PL1817320T3 (no) |
| PT (1) | PT1817320E (no) |
| RU (1) | RU2394040C2 (no) |
| WO (1) | WO2006054098A2 (no) |
| ZA (1) | ZA200705015B (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007031647A (ja) * | 2005-07-29 | 2007-02-08 | Japan Health Science Foundation | 固相合成を利用した超短半減期核種を含む化合物の製造方法およびそれに用いる化合物 |
| CA2632133A1 (en) * | 2005-12-06 | 2007-06-14 | Nihon Medi-Physics Co., Ltd. | Process for production of compound labeled with radioactive fluorine |
| CN101511854B (zh) * | 2006-09-06 | 2012-07-11 | 日本医事物理股份有限公司 | 放射性氟标记有机化合物的制造方法、合成装置及程序 |
| WO2008140616A2 (en) * | 2006-12-21 | 2008-11-20 | Hammersmith Imanet Limited | Nucleophilic radiofluorination using microfabricated devices |
| EP2537854B1 (en) | 2010-02-12 | 2016-12-14 | Tokyo Institute of Technology | Method for producing 18f-labeled compound and high molecular compound to be used in the method |
| KR101430422B1 (ko) * | 2010-04-08 | 2014-08-14 | 지멘스 메디컬 솔루션즈 유에스에이, 인크. | 함수 유기 용매에서 18ｆ-표지된 트레이서의 합성 |
| CN103270004A (zh) * | 2010-12-29 | 2013-08-28 | 通用电气健康护理有限公司 | 洗脱溶液 |
| US9101895B2 (en) | 2011-04-15 | 2015-08-11 | General Electric Company | System for mixing and dispersing microbubble pharmaceuticals |
| WO2013049431A2 (en) * | 2011-09-30 | 2013-04-04 | Ge Healthcare Limited | Reactor for multi-step radiochemistry |
| JP6758065B2 (ja) * | 2016-03-30 | 2020-09-23 | 日本メジフィジックス株式会社 | 放射性標識化合物の製造装置及び製造方法 |
| CN113801173B (zh) * | 2021-09-24 | 2024-03-12 | 上海安迪科正电子技术有限公司 | 一种氟-18标记的脱氧葡糖注射液的制备方法及应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2581558B1 (fr) * | 1985-05-10 | 1987-06-26 | Elf France | Procede de traitement d'un carburant compose d'un melange d'hydrocarbures et d'alcools, et produit d'adsorption selective d'eau |
| GB0115927D0 (en) * | 2001-06-29 | 2001-08-22 | Nycomed Amersham Plc | Solid-phase nucleophilic fluorination |
-
2004
- 2004-11-19 GB GBGB0425501.4A patent/GB0425501D0/en not_active Ceased
-
2005
- 2005-11-18 BR BRPI0518316-2A patent/BRPI0518316A2/pt not_active Application Discontinuation
- 2005-11-18 PT PT05813632T patent/PT1817320E/pt unknown
- 2005-11-18 JP JP2007542100A patent/JP5318416B2/ja active Active
- 2005-11-18 AT AT05813632T patent/ATE472552T1/de not_active IP Right Cessation
- 2005-11-18 CN CN2005800394892A patent/CN101061130B/zh not_active Expired - Fee Related
- 2005-11-18 PL PL05813632T patent/PL1817320T3/pl unknown
- 2005-11-18 KR KR1020077011340A patent/KR101267122B1/ko active IP Right Grant
- 2005-11-18 EP EP05813632A patent/EP1817320B1/en not_active Not-in-force
- 2005-11-18 WO PCT/GB2005/004451 patent/WO2006054098A2/en active Application Filing
- 2005-11-18 NZ NZ554613A patent/NZ554613A/en not_active IP Right Cessation
- 2005-11-18 US US11/719,601 patent/US20090076259A1/en not_active Abandoned
- 2005-11-18 CA CA2584649A patent/CA2584649C/en not_active Expired - Fee Related
- 2005-11-18 RU RU2007115903/04A patent/RU2394040C2/ru active IP Right Revival
- 2005-11-18 ES ES05813632T patent/ES2347165T3/es active Active
- 2005-11-18 DE DE602005022099T patent/DE602005022099D1/de active Active
- 2005-11-18 MX MX2007006052A patent/MX2007006052A/es active IP Right Grant
- 2005-11-18 AU AU2005305624A patent/AU2005305624B2/en not_active Ceased
-
2007
- 2007-04-23 IL IL182740A patent/IL182740A0/en not_active IP Right Cessation
- 2007-06-04 ZA ZA200705015A patent/ZA200705015B/xx unknown
- 2007-06-14 NO NO20073037A patent/NO20073037L/no not_active Application Discontinuation
-
2008
- 2008-01-28 HK HK08101069.6A patent/HK1107353A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0518316A2 (pt) | 2008-11-11 |
| ATE472552T1 (de) | 2010-07-15 |
| US20090076259A1 (en) | 2009-03-19 |
| DE602005022099D1 (de) | 2010-08-12 |
| PT1817320E (pt) | 2010-09-13 |
| JP2008520636A (ja) | 2008-06-19 |
| MX2007006052A (es) | 2007-07-10 |
| NO20073037L (no) | 2007-08-16 |
| CA2584649C (en) | 2013-09-24 |
| PL1817320T3 (pl) | 2010-11-30 |
| AU2005305624A1 (en) | 2006-05-26 |
| NZ554613A (en) | 2011-01-28 |
| ZA200705015B (en) | 2008-09-25 |
| CN101061130A (zh) | 2007-10-24 |
| RU2394040C2 (ru) | 2010-07-10 |
| GB0425501D0 (en) | 2004-12-22 |
| WO2006054098A3 (en) | 2006-08-03 |
| EP1817320B1 (en) | 2010-06-30 |
| EP1817320A2 (en) | 2007-08-15 |
| RU2007115903A (ru) | 2008-12-27 |
| AU2005305624B2 (en) | 2012-05-10 |
| JP5318416B2 (ja) | 2013-10-16 |
| CN101061130B (zh) | 2012-08-15 |
| KR101267122B1 (ko) | 2013-05-24 |
| KR20070084361A (ko) | 2007-08-24 |
| CA2584649A1 (en) | 2006-05-26 |
| IL182740A0 (en) | 2007-07-24 |
| WO2006054098A2 (en) | 2006-05-26 |
| ES2347165T3 (es) | 2010-10-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1107353A1 (en) | Fluoridation process for the synthesis of 2-[18f] fluoro-2-deoxy-d-glucose | |
| IL185419A0 (en) | Improved process for the synthesis of enantiomeric indanylamine derivatives | |
| TW200621776A (en) | Process for the preparation of chiral 8-(3-aminopiperidin-1-yl)-xanthines | |
| EP1554237A4 (en) | PROCESS FOR SYNTHESIS OF ACYLOXYALKYL DERIVATIVES OF GABA ANALOGS | |
| ZA200710143B (en) | Methods of synthesizing 6-alkylaminoquinoline derivatives | |
| HK1215033A1 (zh) | 製備抗水解的聚硅氧烷化合物的方法 | |
| IL197639A0 (en) | Process for synthesis of phenoxy diaminopyrimidine derivatives | |
| SI1807395T1 (sl) | Proces za sintezo N-alkoksiaminov | |
| MX2009005664A (es) | D-isoglutamil-d-triptofano cristalino, y la sal monoamonica de d-isoglutamil-d-triptofano. | |
| IL183591A0 (en) | Novel process for the manufacture of 3-pyrrolidin-2-yl-propionic acid derivatives | |
| IL187884A0 (en) | Process of producing bleach boosters | |
| WO2008019356A3 (en) | Process for the preparation of substituted-1,2,3,4-tetrahydroisoquinoline derivates | |
| EP1836124A4 (en) | SUPRAMOLECULAR COMPLEXES FORMING PHOTOCATALYSTS FOR THE PRODUCTION OF HYDROGEN FROM WATER | |
| HK1105968A1 (en) | Process for production of 3-alkenylcephem compounds 3- | |
| EP1780194A4 (en) | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE ALPHA-FLUOROCARBOXYLIC ACID ESTERS | |
| HK1105950A1 (en) | Process for enantioselective synthesis of single enantiomers of thio- substituted arylmethanesulfinyl derivatives by asymmetric oxidation | |
| HK1097850A1 (en) | Improved synthesis of 2-substituted adenosines | |
| HK1095834A1 (en) | Improved synthesis of 2-substituted adenosines | |
| EP1801228A4 (en) | METHOD FOR PRODUCING ENANTIOMENE-ENRICHED COMPOUNDS | |
| AU2003260813A8 (en) | Improved process for preparation of thiazolidinedione derivatives | |
| AU2003300727A1 (en) | Process for synthesis of alpha-substituted acroleins | |
| IL187714A0 (en) | Process of producing bleach boosters | |
| EP1650185A4 (en) | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID DERIVATIVES | |
| EP1887085A4 (en) | PROCESS FOR PREPARING AN OPTICALLY ACTIVE 2-SUBSTITUTED PROPANAL DERIVATIVE | |
| IL162071A (en) | Process for synthesis of dinitrotetraoxadiazaisowurtzitane (dtiw) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20141118 |