HK110295A - Process for preparing cephalosporin intermediates - Google Patents
Process for preparing cephalosporin intermediatesInfo
- Publication number
- HK110295A HK110295A HK110295A HK110295A HK110295A HK 110295 A HK110295 A HK 110295A HK 110295 A HK110295 A HK 110295A HK 110295 A HK110295 A HK 110295A HK 110295 A HK110295 A HK 110295A
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparing cephalosporin
- cephalosporin intermediates
- intermediates
- preparing
- cephalosporin
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76756185A | 1985-08-20 | 1985-08-20 | |
US06/882,107 US4714760A (en) | 1985-08-20 | 1986-07-11 | Cephalosporin intermediates |
PCT/US1986/001637 WO1987001116A1 (en) | 1985-08-20 | 1986-08-12 | Process for preparing cephalosporin intermediates |
Publications (1)
Publication Number | Publication Date |
---|---|
HK110295A true HK110295A (en) | 1995-07-14 |
Family
ID=27117927
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK110295A HK110295A (en) | 1985-08-20 | 1995-07-06 | Process for preparing cephalosporin intermediates |
Country Status (15)
Country | Link |
---|---|
US (1) | US4714760A (xx) |
EP (1) | EP0233271B1 (xx) |
JP (1) | JPH0615549B2 (xx) |
KR (1) | KR910000419B1 (xx) |
AR (1) | AR241408A1 (xx) |
AT (1) | ATE87000T1 (xx) |
CA (1) | CA1282408C (xx) |
CS (1) | CS262674B2 (xx) |
CY (1) | CY1848A (xx) |
EG (1) | EG18205A (xx) |
FI (1) | FI89051C (xx) |
HK (1) | HK110295A (xx) |
HU (1) | HU201080B (xx) |
WO (1) | WO1987001116A1 (xx) |
YU (1) | YU44810B (xx) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0827520B2 (ja) * | 1986-07-12 | 1996-03-21 | 富士写真フイルム株式会社 | ハロゲン化銀カラ−写真感光材料の処理方法 |
CA1334971C (en) * | 1988-06-22 | 1995-03-28 | Eli Lilly And Company | Intermediate for 1-carba(dethia)cephalosporin |
US4935508A (en) * | 1988-08-23 | 1990-06-19 | Bristol-Myers Company | Process for cephem prodrug esters |
YU81692A (sh) * | 1991-09-10 | 1995-03-27 | Bristol-Myers Co. | Postupak za proizvodnju cefalosporinskog antibiotika |
IL103110A (en) * | 1991-09-10 | 1997-04-15 | Bristol Myers Squibb Co | Anhydrous process for preparing cefepime dihydrochloride hydrate |
CA2099692C (en) * | 1992-07-24 | 2003-09-30 | Gary M. F. Lim | Process for preparing cephalosporin intermediates |
WO1997039002A1 (en) * | 1996-04-12 | 1997-10-23 | Takeda Chemical Industries, Ltd. | Production of 7-aminocephalosporanic acid derivative |
EP1773845A1 (en) * | 2004-07-16 | 2007-04-18 | Hetero Drugs Limited | Process for preparing pure cephalosporine intermediates |
JP2008526944A (ja) * | 2005-01-17 | 2008-07-24 | オーキッド ケミカルズ アンド ファーマシューティカルズ リミテッド | セファロスポリン抗生物質中間体を製造するための改善された方法 |
ITMI20051684A1 (it) * | 2005-09-13 | 2007-03-14 | Harvest Lodge Ltd | Procedimento per la produzione del dicloridrato di amminoacidi |
ITMI20060422A1 (it) * | 2006-03-09 | 2007-09-10 | Harvest Lodge Ltd | Procedimento diretto per la produzione del dicloridrato di un amminoacido |
CN102391289B (zh) * | 2011-12-03 | 2013-09-18 | 齐鲁安替制药有限公司 | 头孢他啶中间体及头孢他啶的合成方法 |
CN102391288B (zh) * | 2011-12-03 | 2013-09-18 | 齐鲁安替制药有限公司 | 头孢匹罗中间体及头孢匹罗的制备方法 |
CN102627659A (zh) * | 2012-04-17 | 2012-08-08 | 黑龙江豪运精细化工有限公司 | 一种头孢哌酮中间体7-tmca的制备方法 |
CN102633813A (zh) * | 2012-04-17 | 2012-08-15 | 黑龙江豪运精细化工有限公司 | 一种头孢唑林钠中间体tda的制备方法 |
CN107201391B (zh) * | 2017-07-04 | 2020-07-07 | 吉林省爱诺德生物工程有限公司 | 一种盐酸头孢吡肟的合成方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4182863A (en) * | 1974-09-03 | 1980-01-08 | Bristol-Myers Company | 7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid |
US4093723A (en) * | 1976-05-19 | 1978-06-06 | Smithkline Corporation | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins |
US4029655A (en) * | 1975-04-11 | 1977-06-14 | Eli Lilly And Company | Method of preparing stable sterile crystalline cephalosporins for parenteral administration |
GB1591439A (en) * | 1976-10-01 | 1981-06-24 | Glaxo Operations Ltd | 7-syn (oxyimino -acylamido) cephalosporins |
BE883453A (fr) * | 1979-05-25 | 1980-11-24 | Glaxo Group Ltd | Composes intermediaires pour la preparation de cephalosporines |
EP0051824B1 (en) * | 1980-11-11 | 1986-01-15 | Takeda Chemical Industries, Ltd. | Improvement in the method for producing 7-aminocephem compounds |
IT8026945A0 (it) * | 1980-12-24 | 1980-12-24 | Isf Spa | Chetoidrossiimminocefalosporine. |
US4336253A (en) * | 1981-03-11 | 1982-06-22 | Eli Lilly And Company | Cephalosporin antibiotics |
DE3118732A1 (de) * | 1981-05-12 | 1982-12-02 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
PL238158A1 (en) * | 1981-09-08 | 1984-11-19 | Lilly Co Eli | Method of obtaining new cephalosporin derivatives |
US4406899A (en) * | 1982-03-04 | 1983-09-27 | Bristol-Myers Company | Cephalosporins |
US4499088A (en) * | 1983-01-04 | 1985-02-12 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
DE3316798A1 (de) * | 1983-05-07 | 1984-11-08 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von cephemverbindungen |
US4540779A (en) * | 1983-06-20 | 1985-09-10 | Eli Lilly And Company | Crystalline 7-(R)-amino-3-(1'pyridiniummethyl)-ceph-3-em-4-carboxylate monohydrochloride monohydrate compound |
US4659812A (en) * | 1985-08-20 | 1987-04-21 | Bristol-Myers Company | Cephalosporin intermediates |
-
1986
- 1986-07-11 US US06/882,107 patent/US4714760A/en not_active Expired - Lifetime
- 1986-08-12 EP EP86905495A patent/EP0233271B1/en not_active Expired - Lifetime
- 1986-08-12 AT AT86905495T patent/ATE87000T1/de not_active IP Right Cessation
- 1986-08-12 KR KR1019870700340A patent/KR910000419B1/ko not_active IP Right Cessation
- 1986-08-12 JP JP61504556A patent/JPH0615549B2/ja not_active Expired - Lifetime
- 1986-08-12 HU HU864052A patent/HU201080B/hu unknown
- 1986-08-12 WO PCT/US1986/001637 patent/WO1987001116A1/en active IP Right Grant
- 1986-08-19 CA CA000516259A patent/CA1282408C/en not_active Expired - Lifetime
- 1986-08-20 AR AR86304973A patent/AR241408A1/es active
- 1986-08-20 CS CS866115A patent/CS262674B2/cs not_active IP Right Cessation
- 1986-08-20 EG EG527/86A patent/EG18205A/xx active
-
1987
- 1987-04-16 FI FI871693A patent/FI89051C/fi not_active IP Right Cessation
- 1987-08-28 YU YU1603/87A patent/YU44810B/xx unknown
-
1995
- 1995-07-06 HK HK110295A patent/HK110295A/xx not_active IP Right Cessation
-
1996
- 1996-03-08 CY CY184896A patent/CY1848A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO1987001116A1 (en) | 1987-02-26 |
HU201080B (en) | 1990-09-28 |
KR910000419B1 (ko) | 1991-01-25 |
FI89051B (fi) | 1993-04-30 |
CS262674B2 (en) | 1989-03-14 |
CA1282408C (en) | 1991-04-02 |
YU44810B (en) | 1991-02-28 |
HUT43853A (en) | 1987-12-28 |
US4714760A (en) | 1987-12-22 |
FI89051C (fi) | 1993-08-10 |
CS611586A2 (en) | 1988-08-16 |
AR241408A1 (es) | 1992-07-31 |
EG18205A (en) | 1993-10-30 |
JPS62502046A (ja) | 1987-08-13 |
FI871693A0 (fi) | 1987-04-16 |
ATE87000T1 (de) | 1993-04-15 |
JPH0615549B2 (ja) | 1994-03-02 |
EP0233271B1 (en) | 1993-03-17 |
KR870700628A (ko) | 1987-12-30 |
EP0233271A4 (en) | 1988-10-20 |
CY1848A (en) | 1996-03-08 |
EP0233271A1 (en) | 1987-08-26 |
YU160387A (en) | 1988-08-31 |
FI871693A (fi) | 1987-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20060811 |