ATE244248T1 - Herstellung von amino cephalosporansäurederivaten - Google Patents
Herstellung von amino cephalosporansäurederivatenInfo
- Publication number
- ATE244248T1 ATE244248T1 AT97915690T AT97915690T ATE244248T1 AT E244248 T1 ATE244248 T1 AT E244248T1 AT 97915690 T AT97915690 T AT 97915690T AT 97915690 T AT97915690 T AT 97915690T AT E244248 T1 ATE244248 T1 AT E244248T1
- Authority
- AT
- Austria
- Prior art keywords
- protected
- group
- trimethylsilylated
- production
- acid derivatives
- Prior art date
Links
- -1 AMINO CEPHALOSPORANIC ACID DERIVATIVES Chemical class 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- FFUAGWLWBBFQJT-UHFFFAOYSA-N hexamethyldisilazane Chemical compound C[Si](C)(C)N[Si](C)(C)C FFUAGWLWBBFQJT-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical class S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9137396 | 1996-04-12 | ||
| JP3527897 | 1997-02-19 | ||
| PCT/JP1997/001224 WO1997039002A1 (en) | 1996-04-12 | 1997-04-10 | Production of 7-aminocephalosporanic acid derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE244248T1 true ATE244248T1 (de) | 2003-07-15 |
Family
ID=26374230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97915690T ATE244248T1 (de) | 1996-04-12 | 1997-04-10 | Herstellung von amino cephalosporansäurederivaten |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0892805B1 (de) |
| AT (1) | ATE244248T1 (de) |
| AU (1) | AU2307297A (de) |
| WO (1) | WO1997039002A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004069833A1 (ja) | 2003-02-07 | 2004-08-19 | Takeda Pharmaceutical Company Limited | 縮環ピリジン誘導体、その製造法および用途 |
| KR100998208B1 (ko) | 2008-04-15 | 2010-12-03 | 주식회사 엔지켐 | 결정성 세포조프란 중간체의 제조방법 |
| CN102336772A (zh) * | 2011-11-07 | 2012-02-01 | 山东诚创医药技术开发有限公司 | 一种盐酸头孢唑兰中间体的制备方法 |
| CN102703559B (zh) * | 2012-06-18 | 2013-09-11 | 山东诚创医药技术开发有限公司 | 7β-氨基-3-[4-(1-甲基-4-吡啶鎓)-2-噻唑硫基]-3-头孢烯-4-羧酸盐酸化物的制备方法 |
| CN103570749A (zh) * | 2013-11-15 | 2014-02-12 | 安徽悦康凯悦制药有限公司 | 一种头孢唑兰制备工艺 |
| CN114315872A (zh) * | 2021-12-25 | 2022-04-12 | 海南海灵化学制药有限公司 | 一种盐酸头孢唑兰中间体的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0612750B1 (de) * | 1984-11-23 | 1999-03-03 | BIOCHEMIE Gesellschaft m.b.H. | Cephalosporinderivative |
| US4714760A (en) * | 1985-08-20 | 1987-12-22 | Bristol-Myers Company | Cephalosporin intermediates |
| JP3094175B2 (ja) * | 1991-09-12 | 2000-10-03 | 株式会社福島製作所 | 推進機を備えた旋回吊り具 |
| TW232695B (de) * | 1992-07-24 | 1994-10-21 | Bristol Myers Squibb Co | |
| JPH08165765A (ja) * | 1994-12-14 | 1996-06-25 | Sekisui Chem Co Ltd | 軒樋吊り具 |
-
1997
- 1997-04-10 AT AT97915690T patent/ATE244248T1/de not_active IP Right Cessation
- 1997-04-10 AU AU23072/97A patent/AU2307297A/en not_active Abandoned
- 1997-04-10 WO PCT/JP1997/001224 patent/WO1997039002A1/en active IP Right Grant
- 1997-04-10 EP EP97915690A patent/EP0892805B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0892805B1 (de) | 2003-07-02 |
| EP0892805A1 (de) | 1999-01-27 |
| AU2307297A (en) | 1997-11-07 |
| WO1997039002A1 (en) | 1997-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0892805 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |