ATE166654T1 - Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten - Google Patents

Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten

Info

Publication number
ATE166654T1
ATE166654T1 AT92904403T AT92904403T ATE166654T1 AT E166654 T1 ATE166654 T1 AT E166654T1 AT 92904403 T AT92904403 T AT 92904403T AT 92904403 T AT92904403 T AT 92904403T AT E166654 T1 ATE166654 T1 AT E166654T1
Authority
AT
Austria
Prior art keywords
producing
hydroxycephem
lactams
derivatives
iii
Prior art date
Application number
AT92904403T
Other languages
English (en)
Inventor
Shigeru Torii
Hideo Tanaka
Masatoshi Taniguchi
Mitio Sasaoka
Takashi Shiroi
Yutaka Kameyama
Ryo Kikuchi
Original Assignee
Otsuka Kagaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Kagaku Kk filed Critical Otsuka Kagaku Kk
Application granted granted Critical
Publication of ATE166654T1 publication Critical patent/ATE166654T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT92904403T 1991-03-13 1992-02-10 Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten ATE166654T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP04708491A JP3195959B2 (ja) 1991-03-13 1991-03-13 ３−ヒドロキシセフェム誘導体の製造法

Publications (1)

Publication Number Publication Date
ATE166654T1 true ATE166654T1 (de) 1998-06-15

Family

ID=12765312

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92904403T ATE166654T1 (de) 1991-03-13 1992-02-10 Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten

Country Status (5)

Country Link
EP (1) EP0529081B1 (de)
JP (1) JP3195959B2 (de)
AT (1) ATE166654T1 (de)
DE (1) DE69225651T2 (de)
WO (1) WO1992016532A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3775818B2 (ja) 1995-03-10 2006-05-17 大塚化学ホールディングス株式会社 ハロゲン化β−ラクタム化合物の製造法
EP1225176B1 (de) * 1995-03-10 2003-07-30 Otsuka Kagaku Kabushiki Kaisha Verfahren zur Herstellung von Exo-Methylenpenam-Derivaten
US5986091A (en) * 1996-03-13 1999-11-16 Otsuka Kagaku Kabushiki Kaisha Process for preparation of β-lactam compounds
JP4953501B2 (ja) * 1999-09-30 2012-06-13 大塚化学株式会社 ３−セフェム誘導体結晶の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU498131B2 (en) * 1974-02-26 1979-02-15 Ciba-Geigy Ag Production of cephems by cyclization
JPS609516B2 (ja) * 1975-03-07 1985-03-11 塩野義製薬株式会社 セフエム骨格の環化製法
JPS51105051A (de) * 1975-02-21 1976-09-17 Shionogi Seiyaku Kk
US4048162A (en) * 1975-10-29 1977-09-13 Eli Lilly And Company Process for preparing 3-hydroxy cephalosporins
US4048157A (en) * 1975-10-29 1977-09-13 Eli Lilly And Company 4(Formylthio)-azetidin-2-ones and ozonization process therefor
JP3007986B2 (ja) * 1990-03-02 2000-02-14 大塚化学株式会社 β―ラクタム誘導体の製法

Also Published As

Publication number Publication date
EP0529081A4 (en) 1993-06-02
EP0529081B1 (de) 1998-05-27
EP0529081A1 (de) 1993-03-03
JP3195959B2 (ja) 2001-08-06
JPH04283584A (ja) 1992-10-08
DE69225651T2 (de) 1998-11-12
WO1992016532A1 (en) 1992-10-01
DE69225651D1 (de) 1998-07-02

Similar Documents

Publication Publication Date Title
DE122011100040I1 (de) Zusammensetzung, verfahren und instrument zur potenzierung der antitumoraktivitat und zur behandlungvon tumoren.
DE69231874D1 (de) Verfahren zur herstellung von 4-substituierten azetidinon-derivaten
PL294101A1 (en) Method of obtaining novel derivatives of benzimidazole
ATE155469T1 (de) Verfahren zur herstellung von cephemderivaten
FR2495612B1 (de)
ATE115580T1 (de) Verfahren und zwischenprodukte zur herstellung von azabicyclo(2.2.2>octan-3-iminen.
ATE166654T1 (de) Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten
ATE71383T1 (de) Verfahren zur herstellung von cephalosporinestern.
AU9462298A (en) Process for producing 3-cephem compounds
ATE244248T1 (de) Herstellung von amino cephalosporansäurederivaten
ES8403866A1 (es) Un metodo de producir un derivado de 4-ciano-2-azetidinona.
ATE138376T1 (de) Verfahren zur herstellung von benzylphthalazinonderivaten und von deren salzen
AU693123B2 (en) New cyclopropyl derivatives, preparation method thereof and applications
DE69311999T2 (de) Verfahren zur Herstellung von Amino-Thiadiazolylacetylhaliden
ES2157952T3 (es) Preparacion de derivados de beta-lactama e intermediarios.
DE3587915D1 (de) Verfahren zur Herstellung von Cephalosporinen.
DE69706632D1 (de) Verfahren zur herstellung von 3-norcephem-verbindungen
ATE244218T1 (de) Verfahren zur herstellung von beta- lactamderivaten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee