DE69225651D1 - Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten - Google Patents

Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten

Info

Publication number
DE69225651D1
DE69225651D1 DE69225651T DE69225651T DE69225651D1 DE 69225651 D1 DE69225651 D1 DE 69225651D1 DE 69225651 T DE69225651 T DE 69225651T DE 69225651 T DE69225651 T DE 69225651T DE 69225651 D1 DE69225651 D1 DE 69225651D1
Authority
DE
Germany
Prior art keywords
hydroxycephem
derivatives
production
halogenated beta
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69225651T
Other languages
English (en)
Other versions
DE69225651T2 (de
Inventor
Shigeru Torii
Hideo Tanaka
Masatoshi - Taniguchi
Mitio Sasaoka
Takashi Shiroi
Yutaka Kameyama
Ryo Kikuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Original Assignee
Otsuka Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd filed Critical Otsuka Chemical Co Ltd
Application granted granted Critical
Publication of DE69225651D1 publication Critical patent/DE69225651D1/de
Publication of DE69225651T2 publication Critical patent/DE69225651T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69225651T 1991-03-13 1992-02-10 Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten Expired - Fee Related DE69225651T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP04708491A JP3195959B2 (ja) 1991-03-13 1991-03-13 ３−ヒドロキシセフェム誘導体の製造法
PCT/JP1992/000126 WO1992016532A1 (en) 1991-03-13 1992-02-10 HALOGENATED β-LACTAM COMPOUND AND PRODUCTION OF 3-HYDROXYCEPHEM DERIVATIVE THEREFROM

Publications (2)

Publication Number Publication Date
DE69225651D1 true DE69225651D1 (de) 1998-07-02
DE69225651T2 DE69225651T2 (de) 1998-11-12

Family

ID=12765312

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69225651T Expired - Fee Related DE69225651T2 (de) 1991-03-13 1992-02-10 Verwendung von halogenierten beta-lactamen zur herstellung von 3-hydroxycephem-derivaten

Country Status (5)

Country Link
EP (1) EP0529081B1 (de)
JP (1) JP3195959B2 (de)
AT (1) ATE166654T1 (de)
DE (1) DE69225651T2 (de)
WO (1) WO1992016532A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3775818B2 (ja) 1995-03-10 2006-05-17 大塚化学ホールディングス株式会社 ハロゲン化β−ラクタム化合物の製造法
EP1225176B1 (de) * 1995-03-10 2003-07-30 Otsuka Kagaku Kabushiki Kaisha Verfahren zur Herstellung von Exo-Methylenpenam-Derivaten
US5986091A (en) * 1996-03-13 1999-11-16 Otsuka Kagaku Kabushiki Kaisha Process for preparation of β-lactam compounds
JP4953501B2 (ja) * 1999-09-30 2012-06-13 大塚化学株式会社 ３−セフェム誘導体結晶の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU498131B2 (en) * 1974-02-26 1979-02-15 Ciba-Geigy Ag Production of cephems by cyclization
JPS609516B2 (ja) * 1975-03-07 1985-03-11 塩野義製薬株式会社 セフエム骨格の環化製法
JPS51105051A (de) * 1975-02-21 1976-09-17 Shionogi Seiyaku Kk
US4048162A (en) * 1975-10-29 1977-09-13 Eli Lilly And Company Process for preparing 3-hydroxy cephalosporins
US4048157A (en) * 1975-10-29 1977-09-13 Eli Lilly And Company 4(Formylthio)-azetidin-2-ones and ozonization process therefor
JP3007986B2 (ja) * 1990-03-02 2000-02-14 大塚化学株式会社 β―ラクタム誘導体の製法

Also Published As

Publication number Publication date
EP0529081A4 (en) 1993-06-02
EP0529081B1 (de) 1998-05-27
EP0529081A1 (de) 1993-03-03
JP3195959B2 (ja) 2001-08-06
JPH04283584A (ja) 1992-10-08
DE69225651T2 (de) 1998-11-12
ATE166654T1 (de) 1998-06-15
WO1992016532A1 (en) 1992-10-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee