DE69628887D1 - Verfahren zur herstellung von beta-lactamderivaten - Google Patents

Verfahren zur herstellung von beta-lactamderivaten

Info

Publication number
DE69628887D1
DE69628887D1 DE69628887T DE69628887T DE69628887D1 DE 69628887 D1 DE69628887 D1 DE 69628887D1 DE 69628887 T DE69628887 T DE 69628887T DE 69628887 T DE69628887 T DE 69628887T DE 69628887 D1 DE69628887 D1 DE 69628887D1
Authority
DE
Germany
Prior art keywords
group
substituent
beta
hydrogen atom
lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69628887T
Other languages
English (en)
Other versions
DE69628887T2 (de
Inventor
Sigeru Torii
Hideo Tanaka
Michio Sasaoka
Daisuke Suzuki
Yutaka Kameyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Original Assignee
Otsuka Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd filed Critical Otsuka Chemical Co Ltd
Application granted granted Critical
Publication of DE69628887D1 publication Critical patent/DE69628887D1/de
Publication of DE69628887T2 publication Critical patent/DE69628887T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE69628887T 1995-03-10 1996-03-01 Verfahren zur herstellung von beta-lactamderivaten Expired - Fee Related DE69628887T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7948995 1995-03-10
JP07948995A JP3775820B2 (ja) 1995-03-10 1995-03-10 ハロゲン化β−ラクタム化合物の製造法
PCT/JP1996/000489 WO1996028421A1 (fr) 1995-03-10 1996-03-01 PROCEDE DE PRODUCTION DE COMPOSES DE β-LACTAME HALOGENES

Publications (2)

Publication Number Publication Date
DE69628887D1 true DE69628887D1 (de) 2003-08-07
DE69628887T2 DE69628887T2 (de) 2004-04-15

Family

ID=13691324

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69628887T Expired - Fee Related DE69628887T2 (de) 1995-03-10 1996-03-01 Verfahren zur herstellung von beta-lactamderivaten

Country Status (6)

Country Link
US (1) US6011151A (de)
EP (1) EP0759427B1 (de)
JP (1) JP3775820B2 (de)
AT (1) ATE244218T1 (de)
DE (1) DE69628887T2 (de)
WO (1) WO1996028421A1 (de)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4918832A (de) * 1972-06-19 1974-02-19
US4011216A (en) * 1975-04-11 1977-03-08 Bristol-Myers Company Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents
US4013648A (en) * 1975-07-23 1977-03-22 Bristol-Myers Company Δ2,3 -0-2-Isocephem-4-carboxylic acid and derivatives as antibacterial agents
DE3687870T2 (de) * 1985-09-09 1993-08-19 Otsuka Pharma Co Ltd 2-oxa-isocephemverbindungen, sie enthaltende zusammensetzungen und verfahren zu deren herstellung.
US5196530A (en) * 1991-03-11 1993-03-23 Otsuka Kagaku Kabushiki Kaisha Process for preparing 2-exo-methylenepenam derivatives
JP3195371B2 (ja) * 1991-03-11 2001-08-06 大塚化学株式会社 セフエム誘導体の製造法
JP3224279B2 (ja) * 1992-07-27 2001-10-29 大塚化学株式会社 セフエム化合物の製造法
JPH08245635A (ja) * 1995-03-10 1996-09-24 Otsuka Chem Co Ltd ２−イソセフェム誘導体の製造法

Also Published As

Publication number Publication date
EP0759427A1 (de) 1997-02-26
WO1996028421A1 (fr) 1996-09-19
JPH08245574A (ja) 1996-09-24
JP3775820B2 (ja) 2006-05-17
EP0759427B1 (de) 2003-07-02
EP0759427A4 (de) 1998-07-08
DE69628887T2 (de) 2004-04-15
ATE244218T1 (de) 2003-07-15
US6011151A (en) 2000-01-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee