ATE246195T1 - Verfahren zur herstellung von exo-methylenpenam- derivaten - Google Patents

Verfahren zur herstellung von exo-methylenpenam- derivaten

Info

Publication number
ATE246195T1
ATE246195T1 AT02004762T AT02004762T ATE246195T1 AT E246195 T1 ATE246195 T1 AT E246195T1 AT 02004762 T AT02004762 T AT 02004762T AT 02004762 T AT02004762 T AT 02004762T AT E246195 T1 ATE246195 T1 AT E246195T1
Authority
AT
Austria
Prior art keywords
exo
methylene
metal
compound
penam derivatives
Prior art date
Application number
AT02004762T
Other languages
English (en)
Inventor
Sigeru Torii
Hideo Tanaka
Michio Sasaoka
Kawauchi Kagasuno
Yutaka Kameyama
Original Assignee
Otsuka Kagaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP07948695A external-priority patent/JP3459134B2/ja
Priority claimed from JP07948595A external-priority patent/JP3775818B2/ja
Application filed by Otsuka Kagaku Kk filed Critical Otsuka Kagaku Kk
Application granted granted Critical
Publication of ATE246195T1 publication Critical patent/ATE246195T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT02004762T 1995-03-10 1996-03-07 Verfahren zur herstellung von exo-methylenpenam- derivaten ATE246195T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP07948695A JP3459134B2 (ja) 1995-03-10 1995-03-10 エキソメチレンペナム化合物の製造法
JP07948595A JP3775818B2 (ja) 1995-03-10 1995-03-10 ハロゲン化β−ラクタム化合物の製造法

Publications (1)

Publication Number Publication Date
ATE246195T1 true ATE246195T1 (de) 2003-08-15

Family

ID=26420504

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02004762T ATE246195T1 (de) 1995-03-10 1996-03-07 Verfahren zur herstellung von exo-methylenpenam- derivaten

Country Status (5)

Country Link
US (2) US5905147A (de)
EP (2) EP0759428A4 (de)
AT (1) ATE246195T1 (de)
DE (1) DE69629321T2 (de)
WO (1) WO1996028422A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10245386A (ja) * 1997-03-05 1998-09-14 Otsuka Chem Co Ltd エキソメチレンペナム化合物の製造方法
EP2010167A2 (de) * 2006-04-13 2009-01-07 Actelion Pharmaceuticals Ltd. Endothelin-rezeptorantagonisten für idiopathische lungenfibrose im frühstadium

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5531790B2 (de) * 1972-12-20 1980-08-20
JPS60149590A (ja) * 1983-10-14 1985-08-07 Shionogi & Co Ltd セフエム化合物の製法
US5196530A (en) * 1991-03-11 1993-03-23 Otsuka Kagaku Kabushiki Kaisha Process for preparing 2-exo-methylenepenam derivatives
JP3224261B2 (ja) * 1991-03-11 2001-10-29 大塚化学株式会社 ２−エキソメチレンペナム誘導体の製造法
JP3195959B2 (ja) * 1991-03-13 2001-08-06 大塚化学株式会社 ３−ヒドロキシセフェム誘導体の製造法
JP3195960B2 (ja) * 1991-03-26 2001-08-06 大塚化学株式会社 ３−ヒドロキシセフェム誘導体の製造法
JPH0562183A (ja) * 1991-09-02 1993-03-12 Tdk Corp 磁気記録媒体の製造方法
JP3234917B2 (ja) * 1992-06-23 2001-12-04 大塚化学株式会社 ２−エキソメチレンペナム誘導体の製造法
JP3541252B2 (ja) * 1993-08-26 2004-07-07 大塚化学ホールディングス株式会社 臭素化β−ラクタム化合物の製造法

Also Published As

Publication number Publication date
US6043356A (en) 2000-03-28
EP1225176A2 (de) 2002-07-24
EP0759428A1 (de) 1997-02-26
DE69629321D1 (de) 2003-09-04
EP1225176A3 (de) 2002-08-07
DE69629321T2 (de) 2004-04-22
EP1225176B1 (de) 2003-07-30
EP0759428A4 (de) 1998-11-11
WO1996028422A1 (fr) 1996-09-19
US5905147A (en) 1999-05-18

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