HK1096406A1 - Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof - Google Patents
Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereofInfo
- Publication number
- HK1096406A1 HK1096406A1 HK07101182A HK07101182A HK1096406A1 HK 1096406 A1 HK1096406 A1 HK 1096406A1 HK 07101182 A HK07101182 A HK 07101182A HK 07101182 A HK07101182 A HK 07101182A HK 1096406 A1 HK1096406 A1 HK 1096406A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- perindopril
- synthesis
- pharmaceutically acceptable
- acceptable salts
- novel method
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03291931A EP1367063B1 (fr) | 2003-07-31 | 2003-07-31 | Nouveau procédé de synthèse du perindopril et de ses sels pharmaceutiquement acceptables |
| PCT/FR2004/002035 WO2005012333A2 (fr) | 2003-07-31 | 2004-07-29 | Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1096406A1 true HK1096406A1 (en) | 2007-06-01 |
Family
ID=29414890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK07101182A HK1096406A1 (en) | 2003-07-31 | 2007-02-01 | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7358372B2 (ja) |
| EP (1) | EP1367063B1 (ja) |
| JP (1) | JP4263743B2 (ja) |
| KR (1) | KR100798560B1 (ja) |
| CN (1) | CN100404548C (ja) |
| AR (1) | AR045151A1 (ja) |
| AT (1) | ATE337332T1 (ja) |
| AU (1) | AU2004261439B2 (ja) |
| BR (1) | BRPI0413169A (ja) |
| CA (1) | CA2533005C (ja) |
| CY (1) | CY1105791T1 (ja) |
| DE (1) | DE60307721T2 (ja) |
| DK (1) | DK1367063T3 (ja) |
| EA (1) | EA008685B1 (ja) |
| ES (1) | ES2271498T3 (ja) |
| GE (1) | GEP20094740B (ja) |
| HK (1) | HK1096406A1 (ja) |
| MA (1) | MA27911A1 (ja) |
| MX (1) | MXPA06001243A (ja) |
| MY (1) | MY139443A (ja) |
| NO (1) | NO333957B1 (ja) |
| NZ (1) | NZ544879A (ja) |
| PL (1) | PL211892B1 (ja) |
| PT (1) | PT1367063E (ja) |
| SI (1) | SI1367063T1 (ja) |
| UA (1) | UA80905C2 (ja) |
| WO (1) | WO2005012333A2 (ja) |
| ZA (1) | ZA200600479B (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI21800A (sl) * | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
| WO2016178591A2 (en) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Genetic markers and treatment of male obesity |
| FR3050380B1 (fr) | 2016-04-20 | 2020-07-10 | Les Laboratoires Servier | Composition pharmaceutique comprenant un betabloquant, un inhibiteur de l'enzyme de conversion et un antihypertenseur ou un ains. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8604144A1 (es) * | 1984-11-21 | 1986-01-16 | Farmhispania | Procedimiento para la obtencion del acido (2s, 3as, 7as)-1-((s)-1-etoxicarbonil-3-fenilpropil) alanil) exahidro-2-indolincarboxilico |
| FR2807431B1 (fr) * | 2000-04-06 | 2002-07-19 | Adir | Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables |
| FR2827860B1 (fr) * | 2001-07-24 | 2004-12-10 | Servier Lab | Nouveau procede de synthese de derives de l'acide (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxyline et application a la synthese du perindopril |
-
2003
- 2003-07-31 EP EP03291931A patent/EP1367063B1/fr not_active Expired - Lifetime
- 2003-07-31 ES ES03291931T patent/ES2271498T3/es not_active Expired - Lifetime
- 2003-07-31 DK DK03291931T patent/DK1367063T3/da active
- 2003-07-31 AT AT03291931T patent/ATE337332T1/de active
- 2003-07-31 PT PT03291931T patent/PT1367063E/pt unknown
- 2003-07-31 SI SI200330430T patent/SI1367063T1/sl unknown
- 2003-07-31 DE DE60307721T patent/DE60307721T2/de not_active Expired - Lifetime
-
2004
- 2004-07-29 AR ARP040102693A patent/AR045151A1/es not_active Application Discontinuation
- 2004-07-29 GE GEAP20049261A patent/GEP20094740B/en unknown
- 2004-07-29 ZA ZA200600479A patent/ZA200600479B/en unknown
- 2004-07-29 EA EA200600250A patent/EA008685B1/ru not_active IP Right Cessation
- 2004-07-29 BR BRPI0413169-0A patent/BRPI0413169A/pt active Search and Examination
- 2004-07-29 CN CNB2004800212090A patent/CN100404548C/zh not_active Expired - Fee Related
- 2004-07-29 MX MXPA06001243A patent/MXPA06001243A/es active IP Right Grant
- 2004-07-29 AU AU2004261439A patent/AU2004261439B2/en not_active Ceased
- 2004-07-29 UA UAA200602130A patent/UA80905C2/xx unknown
- 2004-07-29 KR KR1020067001920A patent/KR100798560B1/ko not_active IP Right Cessation
- 2004-07-29 WO PCT/FR2004/002035 patent/WO2005012333A2/fr active Application Filing
- 2004-07-29 MY MYPI20043053A patent/MY139443A/en unknown
- 2004-07-29 PL PL379631A patent/PL211892B1/pl unknown
- 2004-07-29 NZ NZ544879A patent/NZ544879A/en not_active IP Right Cessation
- 2004-07-29 US US10/566,562 patent/US7358372B2/en not_active Expired - Fee Related
- 2004-07-29 JP JP2006521621A patent/JP4263743B2/ja not_active Expired - Fee Related
- 2004-07-29 CA CA2533005A patent/CA2533005C/fr not_active Expired - Fee Related
-
2006
- 2006-01-17 MA MA28731A patent/MA27911A1/fr unknown
- 2006-02-24 NO NO20060922A patent/NO333957B1/no not_active IP Right Cessation
- 2006-11-16 CY CY20061101673T patent/CY1105791T1/el unknown
-
2007
- 2007-02-01 HK HK07101182A patent/HK1096406A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1089187A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| AP2002002630A0 (en) | Method for synthesis of perindopril and its pharmaceutically acceptable salts | |
| EG26629A (en) | A new process for the synthesis of pyridopril and its pharmaceutically acceptable salts | |
| AU2001248470A1 (en) | Method for synthesis of perindopril and its pharmaceutically acceptable salts | |
| HK1096409A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| HK1089188A1 (en) | Novel method of synthesising perindopril and the pharmaceutically- acceptable salts thereof | |
| EG24152A (en) | Novel method for the synthesis of s-indoline-2-carboxylic acid and application thereof in synthesis of perindopril | |
| HK1096408A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| HK1095839A1 (en) | Method for the synthesis of perindopril and the pharmaceutically-acceptable salts thereof | |
| SI1753720T1 (sl) | Postopek za pripravo perindoprila in njegovih soli | |
| SI1371659T1 (sl) | Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| HK1086281A1 (en) | Novel method for synthesising perindopril and the pharmaceutically acceptable salt thereof | |
| HK1096406A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| HK1096407A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| SI1422236T1 (sl) | Postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1268424T1 (sl) | Postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20180729 |