HK1086273A1 - Semisynthetic macrolide antibiotics of the azalideseries - Google Patents

Semisynthetic macrolide antibiotics of the azalideseries

Info

Publication number
HK1086273A1
HK1086273A1 HK06106121A HK06106121A HK1086273A1 HK 1086273 A1 HK1086273 A1 HK 1086273A1 HK 06106121 A HK06106121 A HK 06106121A HK 06106121 A HK06106121 A HK 06106121A HK 1086273 A1 HK1086273 A1 HK 1086273A1
Authority
HK
Hong Kong
Prior art keywords
azalideseries
macrolide antibiotics
semisynthetic macrolide
semisynthetic
antibiotics
Prior art date
Application number
HK06106121A
Other languages
English (en)
Inventor
Nedjeljko Kujundzic
Mirjana Bukvic Krajacic
Karmen Brajsa
Original Assignee
Pliva Istrazivacki Inst D O O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Istrazivacki Inst D O O filed Critical Pliva Istrazivacki Inst D O O
Publication of HK1086273A1 publication Critical patent/HK1086273A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK06106121A 2002-12-12 2006-05-26 Semisynthetic macrolide antibiotics of the azalideseries HK1086273A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR20020991A HRP20020991A2 (en) 2002-12-12 2002-12-12 N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
PCT/HR2003/000062 WO2004052904A2 (en) 2002-12-12 2003-12-10 Novel semisynthetic macrolide antibiotics of the azalide series

Publications (1)

Publication Number Publication Date
HK1086273A1 true HK1086273A1 (en) 2006-09-15

Family

ID=32500425

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06106121A HK1086273A1 (en) 2002-12-12 2006-05-26 Semisynthetic macrolide antibiotics of the azalideseries

Country Status (25)

Country Link
US (1) US7342000B2 (ko)
EP (1) EP1585753B1 (ko)
JP (1) JP2006510660A (ko)
KR (1) KR20050085555A (ko)
CN (1) CN100335489C (ko)
AR (1) AR042351A1 (ko)
AT (1) ATE327999T1 (ko)
AU (1) AU2003285599A1 (ko)
BR (1) BR0316569A (ko)
CA (1) CA2509599A1 (ko)
CL (1) CL2003002585A1 (ko)
CO (1) CO5640139A2 (ko)
CY (1) CY1106321T1 (ko)
DE (1) DE60305741T2 (ko)
DK (1) DK1585753T3 (ko)
ES (1) ES2266883T3 (ko)
HK (1) HK1086273A1 (ko)
HR (1) HRP20020991A2 (ko)
IS (1) IS2309B (ko)
MX (1) MXPA05006220A (ko)
PL (1) PL377322A1 (ko)
PT (1) PT1585753E (ko)
RS (1) RS80204A (ko)
RU (1) RU2328503C2 (ko)
WO (1) WO2004052904A2 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
US20080200404A1 (en) * 2005-01-14 2008-08-21 Mirjana Bukvic Krajacic Novel Antimalarial 9A-Carbamoyl-Aminoalkyl and 9A-Thiocarbamoyl-Aminoalkyl Azalides
US20080113926A1 (en) * 2005-01-14 2008-05-15 Zrinka Ivezic 9A-Carbamoyl-Y-Aminopropyl- And 9A-Thiocabamoyl-Y-Aminopropyl-Azalides With Antimalarial Activity
JP2009535395A (ja) * 2006-05-03 2009-10-01 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 9a−置換アザリド

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
FR2473525A1 (fr) 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
BE892397A (nl) 1982-03-08 1982-07-01 Marchand Paul Wereldwijde draadloze telefonie voor 10 miljard abonnees
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4492688A (en) 1983-11-25 1985-01-08 Pfizer Inc. Antibacterial cyclic ethers of 9-deoxo-9a-aza-9a-homoerythromycin A and intermediates therefor
US4464527A (en) * 1983-06-30 1984-08-07 Pfizer Inc. Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
MX13723A (es) 1987-11-10 1993-05-01 Pfizer Procedimiento para preparar derivados de 9-desoxo-9a-alil- y propargil-9a-aza-9a-homoeritromicina a
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A
WO1997035590A1 (en) * 1996-03-25 1997-10-02 Platt Chris E 10-aza-9-deoxo-11-deoxy-erythromycin a and derivatives combined with sulfisoxazole
HRP990130B1 (en) * 1999-05-03 2004-06-30 Pliva D D HALOGEN DERIVATIVES 9a-N-(N'-ARYLCARBAMOYL)- AND 9a-N-(N'-ARYLTHIOCARBAMOYL)-9-DEOXO-9a-AZA-9a OF HOMOERYTHROMYCIN A
PL365012A1 (en) * 2000-12-21 2004-12-27 Glaxo Group Limited Macrolide antibiotics
HRP20010146B1 (en) 2001-02-28 2005-10-31 Pliva D.D. 9a-N-(N'-(PHENYLSULFONYL)CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMYCIN A AND OF 5-O-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHRONOLIDE A
HRP20020886A2 (en) 2002-11-11 2005-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. SUBSTITUTED 9a-N-[N'-(BENZENSULFONYL)CARBAMOYL-γ-AMINOPROPYL) AND 9a-N(N' -(?-CYANOETHIL)-N' -(b
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A

Also Published As

Publication number Publication date
PL377322A1 (pl) 2006-01-23
HRP20020991A2 (en) 2005-02-28
MXPA05006220A (es) 2005-11-17
EP1585753B1 (en) 2006-05-31
RU2005121892A (ru) 2006-01-20
US20060252709A1 (en) 2006-11-09
IS7875A (is) 2005-05-31
KR20050085555A (ko) 2005-08-29
DE60305741T2 (de) 2007-06-14
AU2003285599A1 (en) 2004-06-30
EP1585753A2 (en) 2005-10-19
WO2004052904A2 (en) 2004-06-24
CL2003002585A1 (es) 2005-01-28
CA2509599A1 (en) 2004-06-24
BR0316569A (pt) 2005-10-04
CO5640139A2 (es) 2006-05-31
CY1106321T1 (el) 2011-10-12
RU2328503C2 (ru) 2008-07-10
RS80204A (en) 2006-12-15
AU2003285599A8 (en) 2004-06-30
AR042351A1 (es) 2005-06-15
CN100335489C (zh) 2007-09-05
DK1585753T3 (da) 2006-10-02
ES2266883T3 (es) 2007-03-01
IS2309B (is) 2007-10-15
PT1585753E (pt) 2006-08-31
CN1726222A (zh) 2006-01-25
JP2006510660A (ja) 2006-03-30
ATE327999T1 (de) 2006-06-15
US7342000B2 (en) 2008-03-11
WO2004052904A3 (en) 2004-09-02
DE60305741D1 (de) 2006-07-06

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20111210