HK1081964A1 - Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same - Google Patents

Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same

Info

Publication number
HK1081964A1
HK1081964A1 HK06102330A HK06102330A HK1081964A1 HK 1081964 A1 HK1081964 A1 HK 1081964A1 HK 06102330 A HK06102330 A HK 06102330A HK 06102330 A HK06102330 A HK 06102330A HK 1081964 A1 HK1081964 A1 HK 1081964A1
Authority
HK
Hong Kong
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
containing same
imidazopyridine derivatives
Prior art date
Application number
HK06102330A
Other languages
English (en)
Inventor
Sylvain Rault
Jean-Charles Lancelot
Marina Kopp
Daniel-Henri Caignard
Bruno Pfeiffer
Pierre Renard
Jean-Guy Bizot-Espiard
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of HK1081964A1 publication Critical patent/HK1081964A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK06102330A 2002-11-05 2006-02-22 Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same HK1081964A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0213802A FR2846656B1 (fr) 2002-11-05 2002-11-05 Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2003/003277 WO2004043957A1 (fr) 2002-11-05 2003-11-04 Derives d’imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
HK1081964A1 true HK1081964A1 (en) 2006-05-26

Family

ID=32104440

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06102330A HK1081964A1 (en) 2002-11-05 2006-02-22 Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same

Country Status (27)

Country Link
US (1) US7098220B2 (es)
EP (1) EP1558612B1 (es)
JP (1) JP2006508111A (es)
KR (1) KR100717488B1 (es)
CN (1) CN100335480C (es)
AR (1) AR041882A1 (es)
AT (1) ATE337317T1 (es)
AU (1) AU2003292323A1 (es)
BR (1) BR0315800A (es)
CA (1) CA2504008A1 (es)
CY (1) CY1105752T1 (es)
DE (1) DE60307875T2 (es)
DK (1) DK1558612T3 (es)
EA (1) EA008446B1 (es)
ES (1) ES2271653T3 (es)
FR (1) FR2846656B1 (es)
HK (1) HK1081964A1 (es)
MA (1) MA27411A1 (es)
MX (1) MXPA05004791A (es)
MY (1) MY135191A (es)
NO (1) NO20052710L (es)
NZ (1) NZ539599A (es)
PL (1) PL375373A1 (es)
PT (1) PT1558612E (es)
UA (1) UA80579C2 (es)
WO (1) WO2004043957A1 (es)
ZA (1) ZA200503234B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1754483A1 (en) 2005-08-18 2007-02-21 Merck Sante Use of thienopyridone derivatives as AMPK activators and pharmaceutical compositions containing them
FR2903695B1 (fr) 2006-07-13 2008-10-24 Merck Sante Soc Par Actions Si Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2008016730A2 (en) * 2006-08-02 2008-02-07 Targeted Molecular Diagnostics, Llc Compositions and methods for reducing cellular fat
US8163505B2 (en) 2007-05-22 2012-04-24 The Penn State Research Foundation Methods using PBK1 for identifying agents that treat metabolic disorders
US8507473B2 (en) 2008-09-11 2013-08-13 Arena Pharmaceuticals, Inc. 3H-imidazo[4,5-b]pyridin-5-ol derivatives useful in the treatment of GPR81 receptor disorders
MX2011003239A (es) * 2008-09-26 2011-04-28 Merck Sharp & Dohme Nuevos derivados de bencimidazol ciclicos utiles como agentes anti-diabeticos.
CA2741125A1 (en) 2008-10-22 2010-04-29 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
WO2010051206A1 (en) * 2008-10-31 2010-05-06 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
WO2010103040A1 (en) 2009-03-10 2010-09-16 INSERM (Institut National de la Santé et de la Recherche Médicale) 5'-adenosine monophosphate-activated protein kinase (ampk) activators for treating pulmonary hypertension
JP2013510834A (ja) 2009-11-16 2013-03-28 メリテク [1,5]‐ジアゾシン誘導体
CA2786314A1 (en) 2010-02-25 2011-09-01 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
CN103209981B (zh) 2010-09-10 2016-12-28 盐野义制药株式会社 具有ampk活化作用的杂环稠合咪唑衍生物
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
US9527839B2 (en) 2012-08-22 2016-12-27 Merck Sharp & Dohme Corp. Benzimidazole tetrahydropyran derivatives
EP2970277B1 (en) * 2013-03-15 2021-07-28 Knopp Biosciences LLC Imidazo(4,5-b) pyridin-2-yl amides as kv7 channel activators
CA2905242C (en) 2013-03-15 2016-11-29 Pfizer Inc. Indole compounds that activate ampk
HUE064331T2 (hu) 2014-09-12 2024-03-28 Biohaven Therapeutics Ltd Benzoimidazol-1,2-il amidok mint KV7 csatorna aktivátorok
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707984B1 (fr) * 1993-07-23 1995-09-01 Adir Nouvelles pipérazines substituées, leur procédé de préparation et les compositions les contenant.
JP2001506626A (ja) * 1996-12-11 2001-05-22 アヴェンティス ファーマシューティカルズ プロダクツ インコーポレイテッド [1S−[1a,2b,3b,4a(S*)]]−4−[7−[[1−(3−クロロ−2−チエニル)メチル]プロピル]アミノ]−3H−イミダゾ[4,5−b]ピリジン−3−イル]−N−エチル−2,3−ジヒドロキシシクロペンタンカルボキサミドの調製
WO2000012089A1 (en) * 1998-08-31 2000-03-09 Merck & Co., Inc. Novel angiogenesis inhibitors
US6271241B1 (en) * 1999-04-02 2001-08-07 Neurogen Corporation Cycloalkyl and aryl fused aminoalkyl-imidazole derivatives: modulators and GLP-1 receptors

Also Published As

Publication number Publication date
ZA200503234B (en) 2006-06-28
CN100335480C (zh) 2007-09-05
NO20052710L (no) 2005-06-06
BR0315800A (pt) 2005-09-20
DE60307875T2 (de) 2007-04-12
DE60307875D1 (de) 2006-10-05
ATE337317T1 (de) 2006-09-15
AU2003292323A1 (en) 2004-06-03
EP1558612A1 (fr) 2005-08-03
NZ539599A (en) 2007-06-29
PL375373A1 (en) 2005-11-28
CA2504008A1 (fr) 2004-05-27
CY1105752T1 (el) 2010-12-22
PT1558612E (pt) 2006-12-29
EP1558612B1 (fr) 2006-08-23
FR2846656A1 (fr) 2004-05-07
EA200500717A1 (ru) 2005-10-27
FR2846656B1 (fr) 2004-12-24
WO2004043957A1 (fr) 2004-05-27
ES2271653T3 (es) 2007-04-16
DK1558612T3 (da) 2006-12-27
JP2006508111A (ja) 2006-03-09
MA27411A1 (fr) 2005-06-01
KR100717488B1 (ko) 2007-05-14
CN1711261A (zh) 2005-12-21
US7098220B2 (en) 2006-08-29
MY135191A (en) 2008-02-29
EA008446B1 (ru) 2007-06-29
UA80579C2 (en) 2007-10-10
AR041882A1 (es) 2005-06-01
MXPA05004791A (es) 2005-07-22
US20060069117A1 (en) 2006-03-30
KR20050084663A (ko) 2005-08-26

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20111104