HK1075839A1 - Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride - Google Patents

Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride

Info

Publication number
HK1075839A1
HK1075839A1 HK05108042A HK05108042A HK1075839A1 HK 1075839 A1 HK1075839 A1 HK 1075839A1 HK 05108042 A HK05108042 A HK 05108042A HK 05108042 A HK05108042 A HK 05108042A HK 1075839 A1 HK1075839 A1 HK 1075839A1
Authority
HK
Hong Kong
Prior art keywords
indol
piperidin
ylmethyl
dione
pyridin
Prior art date
Application number
HK05108042A
Other languages
English (en)
Inventor
Bush Julie Kay
Faul Margaret Mary
Reutzel-Edens Susan Marie
Original Assignee
Lilly Co Eli
Lilly Corporate Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42799191&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1075839(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli, Lilly Corporate Ct filed Critical Lilly Co Eli
Publication of HK1075839A1 publication Critical patent/HK1075839A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK05108042A 2002-07-12 2005-09-14 Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride HK1075839A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39597602P 2002-07-12 2002-07-12
PCT/US2003/019548 WO2004006928A1 (en) 2002-07-12 2003-07-08 Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride

Publications (1)

Publication Number Publication Date
HK1075839A1 true HK1075839A1 (en) 2005-12-30

Family

ID=42799191

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05108042A HK1075839A1 (en) 2002-07-12 2005-09-14 Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride

Country Status (22)

Country Link
US (2) US8114901B2 (ru)
EP (1) EP1523313B1 (ru)
JP (2) JP4771356B2 (ru)
KR (1) KR100687165B1 (ru)
CN (1) CN100430058C (ru)
AU (1) AU2003280958B9 (ru)
CA (1) CA2393720C (ru)
DE (1) DE60317675T2 (ru)
EA (1) EA007463B1 (ru)
EC (1) ECSP055537A (ru)
ES (1) ES2295605T3 (ru)
HK (1) HK1075839A1 (ru)
HR (1) HRP20050035B1 (ru)
IL (1) IL165747A (ru)
NO (1) NO330254B1 (ru)
NZ (1) NZ537137A (ru)
PE (1) PE20040652A1 (ru)
PL (1) PL373046A1 (ru)
TW (1) TWI315667B (ru)
UA (1) UA78801C2 (ru)
WO (1) WO2004006928A1 (ru)
ZA (1) ZA200500065B (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101146532B (zh) 2005-01-21 2012-05-09 阿斯泰克斯治疗有限公司 药物化合物
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
CN102405015B (zh) 2009-03-02 2017-01-18 第七感生物系统有限公司 用于分析可提取介质的装置和方法
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
CN103068308B (zh) 2010-07-16 2016-03-16 第七感生物系统有限公司 用于流体传输装置的低压环境
EP2630121A1 (en) * 2010-09-30 2013-08-28 Wisconsin Alumni Research Foundation (20r,25s)-2-methylene-19,26-dinor-1alpha, 25-dihydroxyvitamin d3 in crystalline form
EP2992827B1 (en) 2010-11-09 2017-04-19 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
KR102237667B1 (ko) 2011-04-29 2021-04-12 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
AU2017285384A1 (en) 2016-06-17 2019-02-07 Cells For Cells, S.P.A. Gelatin polymer derived from natural sources of cold-adapted marine species and uses thereof
IL293480B2 (en) 2016-08-10 2024-02-01 Hoffmann La Roche Medical preparations containing AKT protein kinase inhibitors
JOP20190025A1 (ar) 2016-09-01 2019-02-19 Denovo Biopharma Llc طرق وتركيبة لتوقع نشاط إنزاستورين
CN116199590A (zh) * 2022-12-26 2023-06-02 湖北美林药业有限公司 一种盐酸多巴酚丁胺及其注射剂

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3625738A1 (de) * 1986-07-30 1988-02-11 Goedecke Ag 2-acyloxypropylamin-derivate, verfahren zu deren herstellung und deren verwendung
US4808613A (en) * 1986-11-21 1989-02-28 Bristol-Myers Company Rebeccamycin derivative containing pharmaceutical composition
US4785085A (en) 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
US4923986A (en) * 1987-03-09 1990-05-08 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance K-252
DE3803620A1 (de) 1988-02-06 1989-08-17 Goedecke Ag Indolocarbazol-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel
CZ280738B6 (cs) * 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
GB8904161D0 (en) * 1989-02-23 1989-04-05 Hoffmann La Roche Substituted pyrroles
PT93947B (pt) 1989-05-05 1996-11-29 Goedecke Ag Processo para a preparacao de novos derivados de maleinimidas e de composicoes farmaceuticas que os contem
US5380746A (en) * 1989-05-05 1995-01-10 Goedecke Aktiengesellschaft Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5489608A (en) * 1989-12-21 1996-02-06 Goedecke Aktiengesellschaft Indolocarbazole derivatives and the use thereof
DE4005969A1 (de) 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4005970A1 (de) 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte maleinimide, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
CA2046801C (en) 1990-08-07 2002-02-26 Peter D. Davis Substituted pyrroles
US5292747A (en) * 1990-08-07 1994-03-08 Hoffman-La Roche Inc. Substituted pyrroles
GB9123396D0 (en) 1991-11-04 1991-12-18 Hoffmann La Roche A process for the manufacture of substituted maleimides
US5461146A (en) 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
DE4243321A1 (de) 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
US5484926A (en) 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
AU678435B2 (en) 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
SE501711C2 (sv) * 1993-09-08 1995-05-02 Jimek Int Ab Sprayrör för en duktvättanordning vid en tryckpress
US5624949A (en) * 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
US5545636A (en) * 1993-12-23 1996-08-13 Eli Lilly And Company Protein kinase C inhibitors
PT817627E (pt) * 1993-12-23 2005-07-29 Lilly Co Eli Inibidores da proteina cinase c
US5481003A (en) * 1994-06-22 1996-01-02 Eli Lilly And Company Protein kinase C inhibitors
PE91598A1 (es) * 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
GB9620390D0 (en) * 1996-09-30 1996-11-13 Eisai London Res Lab Ltd Substances and their uses
AU6335600A (en) * 1999-07-29 2001-02-19 Eli Lilly And Company A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-metho yphenyl)benzo[b]thiophene hydrochloride
WO2001030331A2 (en) * 1999-10-22 2001-05-03 Eli Lilly And Company Therapeutic compositions including protein kinase c inhibitors
WO2002002116A2 (en) * 2000-06-29 2002-01-10 Eli Lilly And Company Therapeutic treatment of cancer with a protein kinase c inhibitor
AU2001271257A1 (en) * 2000-06-29 2002-01-14 Eli Lilly And Company Use of a protein kinase c inhibitor to enhance the clinical efficacy of anti-neoplastic chemotherapeutic agents and radiation therapy
RU2004135382A (ru) * 2002-06-05 2005-06-27 Янссен Фармацевтика Н.В. (Be) Замещенные пирролины в качестве ингибиторов киназы

Also Published As

Publication number Publication date
JP2011144182A (ja) 2011-07-28
PE20040652A1 (es) 2004-10-05
CN1668304A (zh) 2005-09-14
PL373046A1 (en) 2005-08-08
JP2006502115A (ja) 2006-01-19
CA2393720A1 (en) 2004-01-16
ES2295605T3 (es) 2008-04-16
DE60317675T2 (de) 2008-10-30
IL165747A0 (en) 2006-01-15
AU2003280958B2 (en) 2008-12-18
WO2004006928A1 (en) 2004-01-22
AU2003280958B9 (en) 2009-07-02
NZ537137A (en) 2007-11-30
EA200500191A1 (ru) 2005-06-30
UA78801C2 (en) 2007-04-25
IL165747A (en) 2010-05-17
DE60317675D1 (de) 2008-01-03
TWI315667B (en) 2009-10-11
KR20050021453A (ko) 2005-03-07
KR100687165B1 (ko) 2007-02-27
HRP20050035A2 (en) 2005-04-30
TW200408392A (en) 2004-06-01
US20070270465A1 (en) 2007-11-22
EP1523313A1 (en) 2005-04-20
EA007463B1 (ru) 2006-10-27
ECSP055537A (es) 2005-03-10
ZA200500065B (en) 2006-03-29
EP1523313B1 (en) 2007-11-21
US8114901B2 (en) 2012-02-14
AU2003280958B8 (en) 2009-02-19
CN100430058C (zh) 2008-11-05
JP4771356B2 (ja) 2011-09-14
CA2393720C (en) 2010-09-14
AU2003280958A1 (en) 2004-02-02
JP5242718B2 (ja) 2013-07-24
HRP20050035B1 (hr) 2013-07-31
NO20050676L (no) 2005-02-09
NO330254B1 (no) 2011-03-14
US20050288332A1 (en) 2005-12-29

Similar Documents

Publication Publication Date Title
HK1075839A1 (en) Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride
SI1555267T1 (sl) 2,3-DIHIDRO-6-NITROIMIDAZO(2,1-b)OKSAZOLI
SI2308855T1 (sl) 2,4-diaminopirimidinski derivati
DE60302150D1 (en) N-substituiete heteroaryloxy-aryl-spiro-pyrimidine-2,4,6-trion metalloproteinase inhibitoren
HK1090368A1 (en) 2,3,6-trisubstituted-4-pyrimidone derivatives
HK1061852A1 (en) 4,5-dihydro-ih-pyrazole derivatives having cb1-antagonistic activity
GB0219896D0 (en) Dihydropyridine derivatives
IL160081A0 (en) Novel 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity
EP1542699A4 (en) COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
EP1414443A4 (en) BENZIMIDAZO 4,5-f] ISOCHINOLINONE DERIVATIVES
HK1078568A1 (en) 2-(2,6-dichlorophenyl)-diarylimidazoles
HK1085462A1 (zh) 哌啶衍生物、其製備方法和應用
PL377187A1 (pl) Związki ze skondensowanym pierścieniem 1,3-dihydroimidazolowym
IL153224A0 (en) 1,4-dihydropyridines as bradykinin antagonists
GB2361235B (en) 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides
MXPA03006991A (es) Derivados de piperidina como antagonistas de neurocinina 1.
AU2003299648A1 (en) Substituted 4-phenyl-(1,3)-dioxanes
AU2003297594A8 (en) Crystalline form
AU2003300883A8 (en) Substituted 1-benzoyl-3-cyano-pyrrolo(1,2-a)quinolines
IL162310A0 (en) 3,4-Dihydro-1h-isoquinoloin-2-yl-derivatives
AU2003269949A1 (en) Substituted 1,4-pyrazine derivatives
AU2003258598A1 (en) Substituted 1,2,3,4-tetrahydroquinoline derivatives
IL159965A0 (en) Novel 2,4-diaminothiazole derivatives
PT1497256E (pt) Compostos de 1,5-diaminopentan-3-ol substituídos
GB0228533D0 (en) Crystalline form

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150708