HK1070077A1 - Chimeric tnf ligands - Google Patents

Chimeric tnf ligands

Info

Publication number
HK1070077A1
HK1070077A1 HK05103074.8A HK05103074A HK1070077A1 HK 1070077 A1 HK1070077 A1 HK 1070077A1 HK 05103074 A HK05103074 A HK 05103074A HK 1070077 A1 HK1070077 A1 HK 1070077A1
Authority
HK
Hong Kong
Prior art keywords
tnfα
cell
sequence encoding
chimeric
subdomain
Prior art date
Application number
HK05103074.8A
Other languages
English (en)
Inventor
Charles E Prussak
Thomas J Kipps
Mark J Cantwell
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of HK1070077A1 publication Critical patent/HK1070077A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK05103074.8A 2001-12-06 2005-04-12 Chimeric tnf ligands HK1070077A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/006,305 US7786282B2 (en) 2001-12-06 2001-12-06 Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
PCT/US2002/039245 WO2003050254A2 (en) 2001-12-06 2002-12-05 Novel chimeric tnf ligands

Publications (1)

Publication Number Publication Date
HK1070077A1 true HK1070077A1 (en) 2005-06-10

Family

ID=21720251

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05103074.8A HK1070077A1 (en) 2001-12-06 2005-04-12 Chimeric tnf ligands

Country Status (17)

Country Link
US (3) US7786282B2 (xx)
EP (1) EP1465912B9 (xx)
JP (1) JP4610194B2 (xx)
CN (1) CN1316022C (xx)
AT (1) ATE414103T1 (xx)
AU (2) AU2002362205B2 (xx)
CA (1) CA2469494A1 (xx)
CY (1) CY1110473T1 (xx)
DE (1) DE60229881D1 (xx)
DK (1) DK1465912T3 (xx)
ES (1) ES2316638T3 (xx)
HK (1) HK1070077A1 (xx)
IL (2) IL162357A0 (xx)
PT (1) PT1465912E (xx)
SI (1) SI1465912T1 (xx)
TW (1) TWI275644B (xx)
WO (1) WO2003050254A2 (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7070771B1 (en) * 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
US7786282B2 (en) * 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
US20080318886A1 (en) * 2006-12-05 2008-12-25 Prussak Charles E Methods of Increasing Cancer Sensitivity to Chemotherapeutic Agents Using Chimeric ISF35
PL391627A1 (pl) * 2010-06-25 2012-01-02 Adamed Spółka Z Ograniczoną Odpowiedzialnością Przeciwnowotworowe białko fuzyjne
PL219845B1 (pl) * 2011-01-05 2015-07-31 Adamed Spółka Z Ograniczoną Odpowiedzialnością Przeciwnowotworowe białko fuzyjne
GB201406705D0 (en) 2014-04-15 2014-05-28 Univ Liverpool Fusion proteins,polynucleotides,expression vectors, and their uses
WO2016154286A1 (en) 2015-03-23 2016-09-29 Virocyt, Inc. Evaluating biological material for unassociated virus-size particles of adenovirus or adeno-associated virus viral type
US20180244750A1 (en) 2015-11-02 2018-08-30 Memgen, Llc Methods for treatment of cancer
HUP1600456A2 (en) 2016-07-19 2018-01-29 Richter Gedeon Nyrt Novel cell-based tnf-alpha binding assay
US11298420B2 (en) 2016-12-21 2022-04-12 Memgen, Llc Armed oncolytic viruses
AR120470A1 (es) * 2019-11-13 2022-02-16 Crispr Therapeutics Ag Métodos para fabricar células t car
WO2022216565A1 (en) * 2021-04-05 2022-10-13 Implicyte, Inc. Armed chimeric oncolytic viruses
WO2024064637A2 (en) * 2022-09-19 2024-03-28 Emendobio Inc. Biallelic knockout of faslg

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US22017A (en) * 1858-11-09 Pen-fountain
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EP0317641B1 (en) 1987-05-29 1993-03-17 Sagami Chemical Research Center Fused protein containing lymphotoxin
ES2097766T3 (es) 1989-08-16 1997-04-16 Chiron Corp Composiciones para la inhibicion de la formacion de hormonas proteicas y sus usos.
US5519119A (en) 1990-09-21 1996-05-21 Ishihara Sangyo Kaisha Ltd. Muteins of TNF pharmaceutical compositions and a method of making
CA2055168A1 (en) 1990-11-21 1992-05-22 Walter Fiers Tnf-muteins
US5962406A (en) 1991-10-25 1999-10-05 Immunex Corporation Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same
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ES2197149T3 (es) 1992-03-30 2004-01-01 Immunex Corporation Proteinas de fusion que comprende receptores para dos factores de necrosis tumoral.
SK376492A3 (en) 1992-04-02 1995-06-07 Hoffmann La Roche Tnf - muteins and method of their production
ATE311895T1 (de) 1992-05-26 2005-12-15 Immunex Corp Neue zytokine die cd30 binden
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AU5098493A (en) 1992-08-21 1994-03-15 Schering Corporation Cd40 ligand, anti cd40 antibodies, and soluble cd40
US5540926A (en) 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation
US5573924A (en) 1992-09-08 1996-11-12 Immunex Corporation CD27 ligand
US5565321A (en) 1993-01-22 1996-10-15 Immunex Corporation Detection of mutations in a CD40 ligand gene
NZ262576A (en) 1993-01-22 1999-09-29 Immunex Corp Detection and treatment of mutations in a cd-40 ligand gene
US5830463A (en) 1993-07-07 1998-11-03 University Technology Corporation Yeast-based delivery vehicles
US5861310A (en) 1993-11-03 1999-01-19 Dana-Farber Cancer Institute Tumor cells modified to express B7-2 with increased immunogenicity and uses therefor
JPH08127594A (ja) 1993-11-10 1996-05-21 Mochida Pharmaceut Co Ltd Ｆａｓ抗原に結合する新規蛋白質およびそれをコードするＤＮＡ
AU1059095A (en) 1993-11-24 1995-06-13 Australian National University, The Treatment of viral disease with cd40l peptide
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EP0739350B1 (en) 1994-01-07 2008-02-27 Mochida Pharmaceutical Co., Ltd. Ligand that binds fas antigen
JP3881691B2 (ja) 1994-04-28 2007-02-14 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド Ｂ細胞の増殖方法及び分化方法並びにその使用
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US5759536A (en) 1994-05-27 1998-06-02 University Technology Corporation Use of fas ligand to supress T-lymphocyte-mediated immune responses
WO1996003141A1 (en) 1994-07-22 1996-02-08 F. Hoffmann-La Roche Ag Pharmaceutical compositions comprising a chimaeric tnf binding protein
GB9425060D0 (en) 1994-12-13 1995-02-08 Univ Birmingham Carcinoma treatment
US5888764A (en) 1995-01-20 1999-03-30 Uab Research Foundation Human fas gene promoter region
US6017527A (en) 1996-07-10 2000-01-25 Immunex Corporation Activated dendritic cells and methods for their activation
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
US7070771B1 (en) * 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
US6016832A (en) * 1997-04-16 2000-01-25 Woodward Governor Company Valve for controlling gas mass flow
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US6451759B1 (en) * 1998-01-14 2002-09-17 The Regents Of The University Of California Noncleavable Fas ligand
US7300774B1 (en) * 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
WO2001078769A2 (en) 2000-04-12 2001-10-25 University Of South Florida Regulation of systemic immune responses utilizing soluble cd40
US7786282B2 (en) * 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
US7495090B2 (en) * 2002-05-23 2009-02-24 The Regents Of The University Of California Nucleic acids encoding chimeric CD154 polypeptides
GB2392158B (en) 2002-08-21 2005-02-16 Proimmune Ltd Chimeric MHC protein and oligomer thereof

Also Published As

Publication number Publication date
US20050048476A1 (en) 2005-03-03
US20110008842A1 (en) 2011-01-13
SI1465912T1 (sl) 2009-04-30
US7964712B2 (en) 2011-06-21
US7786282B2 (en) 2010-08-31
EP1465912B1 (en) 2008-11-12
ES2316638T3 (es) 2009-04-16
JP4610194B2 (ja) 2011-01-12
ATE414103T1 (de) 2008-11-15
DK1465912T3 (da) 2009-03-16
CY1110473T1 (el) 2015-04-29
WO2003050254A2 (en) 2003-06-19
JP2005511086A (ja) 2005-04-28
CN1316022C (zh) 2007-05-16
DE60229881D1 (de) 2008-12-24
EP1465912A4 (en) 2005-04-13
PT1465912E (pt) 2009-02-19
AU2002362205A1 (en) 2003-06-23
EP1465912B9 (en) 2009-08-12
IL162357A (en) 2010-12-30
AU2002362205B2 (en) 2009-12-10
WO2003050254A3 (en) 2004-03-04
EP1465912A2 (en) 2004-10-13
TWI275644B (en) 2007-03-11
CA2469494A1 (en) 2003-06-19
US20120116052A1 (en) 2012-05-10
TW200301777A (en) 2003-07-16
AU2010200912A1 (en) 2010-04-01
CN1612890A (zh) 2005-05-04
IL162357A0 (en) 2005-11-20

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20161205