HK1069413A1 - Methods of treating psychosis and schizophrenia based on polymorphisms in the cntf gene - Google Patents

Methods of treating psychosis and schizophrenia based on polymorphisms in the cntf gene

Info

Publication number
HK1069413A1
HK1069413A1 HK05102010.7A HK05102010A HK1069413A1 HK 1069413 A1 HK1069413 A1 HK 1069413A1 HK 05102010 A HK05102010 A HK 05102010A HK 1069413 A1 HK1069413 A1 HK 1069413A1
Authority
HK
Hong Kong
Prior art keywords
polymorphisms
methods
cntf gene
treating psychosis
schizophrenia based
Prior art date
Application number
HK05102010.7A
Other languages
English (en)
Inventor
Sridhar Kudaravalli
Mihael Hristos Polymeropoulos
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1069413A1 publication Critical patent/HK1069413A1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/30—Psychoses; Psychiatry
    • G01N2800/302—Schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK05102010.7A 2001-12-10 2005-03-08 Methods of treating psychosis and schizophrenia based on polymorphisms in the cntf gene HK1069413A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33983501P 2001-12-10 2001-12-10
PCT/EP2002/013937 WO2003054226A2 (en) 2001-12-10 2002-12-09 Methods of treating psychosis and schizophrenia based on a polymorphism in the ctf gene

Publications (1)

Publication Number Publication Date
HK1069413A1 true HK1069413A1 (en) 2005-05-20

Family

ID=23330814

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05102010.7A HK1069413A1 (en) 2001-12-10 2005-03-08 Methods of treating psychosis and schizophrenia based on polymorphisms in the cntf gene

Country Status (16)

Country Link
US (3) US20050059006A1 (ja)
EP (1) EP1458888B1 (ja)
JP (2) JP2005512576A (ja)
CN (1) CN1612941B (ja)
AT (1) ATE503845T1 (ja)
AU (1) AU2002358110A1 (ja)
BR (1) BRPI0214821B8 (ja)
CA (1) CA2468972A1 (ja)
CY (1) CY1111594T1 (ja)
DE (1) DE60239634D1 (ja)
DK (1) DK1458888T3 (ja)
ES (1) ES2364037T3 (ja)
HK (1) HK1069413A1 (ja)
PT (1) PT1458888E (ja)
SI (1) SI1458888T1 (ja)
WO (1) WO2003054226A2 (ja)

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US9328387B2 (en) 2007-09-10 2016-05-03 Vanda Pharmaceuticals, Inc. Antipsychotic treatment based on SNP genotype
WO2009036100A2 (en) * 2007-09-10 2009-03-19 Vanda Pharmaceuticals, Inc. Prediction of qt prolongation based on snp genotype
PL2222300T3 (pl) 2007-12-13 2015-02-27 Vanda Pharmaceuticals Inc Sposób i skład preparatu do leczenia chorób z udziałem receptorów serotoniny
ES2527515T3 (es) 2007-12-13 2015-01-26 Vanda Pharmaceuticals Inc. Método y composición para tratar una afección mediada por un adrenoceptor alfa
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CA2742074A1 (en) * 2008-10-29 2010-08-26 Janssen Pharmaceutica Nv Methods of treating psychosis and schizophrenia based on polymorphisms in the erbb4 gene
EP2430183B1 (en) 2009-05-15 2014-12-17 Vanda Pharmaceuticals Inc. Antipsychotic treatment based on drd2 or ankk1 snp genotype
CN104203240A (zh) 2012-03-14 2014-12-10 万达制药公司 用于治疗精神疾病的伊潘立酮代谢物
US10877498B2 (en) * 2017-10-27 2020-12-29 Brasscraft Manufacturing Company Excess flow and thermal valve
US20210319849A1 (en) * 2018-08-28 2021-10-14 Koninklijke Philips N.V. Method for assessing genome alignment basis
US11214827B2 (en) * 2018-08-30 2022-01-04 Vanda Pharmaceuticals Inc. Genetic markers for enhancing efficacy of antipsychotic treatment with iloperidone
WO2020216832A1 (en) * 2019-04-24 2020-10-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the response of antipsychotic drugs
CN110184345B (zh) * 2019-07-11 2020-05-05 南京先声医学检验有限公司 用于检测精神及神经类疾病用药相关snp位点的引物组、应用、产品及方法
CN111187829A (zh) * 2020-02-24 2020-05-22 内蒙古医科大学 Lp基因启动子区甲基化检测引物与检测方法及其应用

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Also Published As

Publication number Publication date
DE60239634D1 (de) 2011-05-12
DK1458888T3 (da) 2011-06-20
EP1458888A2 (en) 2004-09-22
ATE503845T1 (de) 2011-04-15
WO2003054226A3 (en) 2004-04-01
BRPI0214821B8 (pt) 2021-07-27
US20050059006A1 (en) 2005-03-17
CA2468972A1 (en) 2003-07-03
BRPI0214821B1 (pt) 2015-07-07
CY1111594T1 (el) 2015-10-07
WO2003054226A2 (en) 2003-07-03
US20080027106A1 (en) 2008-01-31
JP5785697B2 (ja) 2015-09-30
BR0214821A (pt) 2004-11-03
US20090239908A1 (en) 2009-09-24
ES2364037T3 (es) 2011-08-23
CN1612941A (zh) 2005-05-04
AU2002358110A8 (en) 2003-07-09
CN1612941B (zh) 2011-11-16
EP1458888B1 (en) 2011-03-30
PT1458888E (pt) 2011-06-01
AU2002358110A1 (en) 2003-07-09
JP2011006422A (ja) 2011-01-13
JP2005512576A (ja) 2005-05-12
SI1458888T1 (sl) 2011-07-29
US8460867B2 (en) 2013-06-11

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