HK1055947A1 - Novel branched substituted amino derivatives of 3-amino-1-phenyl-1H-Ä1,2,4Ütriazol, methods for producing them and pharmaceutical compositions containing them - Google Patents

Novel branched substituted amino derivatives of 3-amino-1-phenyl-1H-Ä1,2,4Ütriazol, methods for producing them and pharmaceutical compositions containing them

Info

Publication number
HK1055947A1
HK1055947A1 HK03108164A HK03108164A HK1055947A1 HK 1055947 A1 HK1055947 A1 HK 1055947A1 HK 03108164 A HK03108164 A HK 03108164A HK 03108164 A HK03108164 A HK 03108164A HK 1055947 A1 HK1055947 A1 HK 1055947A1
Authority
HK
Hong Kong
Prior art keywords
amino
4ütriazol
phenyl
producing
methods
Prior art date
Application number
HK03108164A
Other languages
English (en)
Inventor
Michel Geslin
Danielle Gully
Jean-Pierre Maffrand
Pierre Roger
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of HK1055947A1 publication Critical patent/HK1055947A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK03108164A 1999-12-17 2003-11-11 Novel branched substituted amino derivatives of 3-amino-1-phenyl-1H-Ä1,2,4Ütriazol, methods for producing them and pharmaceutical compositions containing them HK1055947A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9915935A FR2802530B1 (fr) 1999-12-17 1999-12-17 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
PCT/FR2000/003536 WO2001044207A2 (fr) 1999-12-17 2000-12-14 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2 4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
HK1055947A1 true HK1055947A1 (en) 2004-01-30

Family

ID=9553380

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03108164A HK1055947A1 (en) 1999-12-17 2003-11-11 Novel branched substituted amino derivatives of 3-amino-1-phenyl-1H-Ä1,2,4Ütriazol, methods for producing them and pharmaceutical compositions containing them

Country Status (34)

Country Link
US (1) US6806282B2 (ja)
EP (1) EP1242389B1 (ja)
JP (1) JP4146641B2 (ja)
KR (1) KR100705525B1 (ja)
CN (1) CN1293061C (ja)
AR (1) AR031837A1 (ja)
AT (1) ATE264847T1 (ja)
AU (1) AU780711B2 (ja)
BR (1) BR0017023A (ja)
CA (1) CA2398772C (ja)
CO (1) CO5251379A1 (ja)
CZ (1) CZ302460B6 (ja)
DE (1) DE60010126T2 (ja)
DK (1) DK1242389T3 (ja)
EA (1) EA004957B1 (ja)
EE (1) EE04778B1 (ja)
ES (1) ES2219436T3 (ja)
FR (1) FR2802530B1 (ja)
HK (1) HK1055947A1 (ja)
HU (1) HUP0204080A3 (ja)
IL (2) IL150037A0 (ja)
IS (1) IS2315B (ja)
ME (1) MEP12108A (ja)
MX (1) MXPA02006033A (ja)
NO (1) NO20022828L (ja)
PL (1) PL203819B1 (ja)
PT (1) PT1242389E (ja)
RS (1) RS50289B (ja)
SK (1) SK285994B6 (ja)
TR (2) TR200401775T4 (ja)
TW (1) TWI289554B (ja)
UA (1) UA73333C2 (ja)
WO (1) WO2001044207A2 (ja)
ZA (1) ZA200204422B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE455546T1 (de) * 2003-08-06 2010-02-15 Vertex Pharma Aminotriazol-verbindungen als proteinkinase- hemmer
JO3019B1 (ar) 2006-04-19 2016-09-05 Janssen Pharmaceutica Nv ثلاثي مستبدل 4،2،1-ثلاثي زولات
AU2008313776B2 (en) 2007-10-18 2013-12-05 Janssen Pharmaceutica Nv Trisubstituted 1,2,4-triazoles
JO2784B1 (en) 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
CA2714662C (en) 2008-03-19 2016-05-10 Janssen Pharmaceutica Nv Trisubstituted 1,2,4-triazoles as nicotinic acetylcholine receptor modulators
CL2009001125A1 (es) 2008-05-09 2011-02-11 Janssen Pharmaceutica Nv Compuestos derivados de pirazol trisustituido, moduladores alostericos positivos de los receptores ach nicotinicos; composicion farmaceutica que los comprende; proceso de preparacion de la composicion; y su uso en el tratamiento de enfermedades de snc o inflamatorias.
WO2012054366A2 (en) * 2010-10-21 2012-04-26 Merck Sharp & Dohme Corp. Substituted amino-triazolyl pde10 inhibitors
KR102258522B1 (ko) 2014-01-21 2021-05-31 뉴로크린 바이오사이언시즈 인코퍼레이티드 선천성 부신 과형성 치료를 위한 ｃｒｆ1 수용체 길항제
CN104059027B (zh) * 2014-07-01 2015-10-28 河北大学 一类含1,2,4-三唑的(e)-甲氧基亚氨基苯乙酸甲酯类化合物及其制备方法和用途
MX2022002881A (es) * 2019-09-25 2022-06-08 Oncoarendi Therapeutics Sa Proceso para la produccion de 5-(4-((2s,5s)-5-(4-clorobencil)-2-me tilmorfolino)piperidin-1-il)-1h-1,2,4-triazol-3-amina.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3869167D1 (de) * 1987-03-27 1992-04-23 Kumiai Chemical Industry Co Phenyltriazol-derivate und insectizid.
US5795905A (en) * 1995-06-06 1998-08-18 Neurocrine Biosciences, Inc. CRF receptor antagonists and methods relating thereto
FR2763337B1 (fr) * 1997-05-13 1999-08-20 Sanofi Sa Nouveaux derives du triazole, un procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
HUP0204080A3 (en) 2005-01-28
ZA200204422B (en) 2003-11-26
WO2001044207B1 (fr) 2002-06-06
CA2398772A1 (fr) 2001-06-21
JP2003516975A (ja) 2003-05-20
FR2802530B1 (fr) 2002-02-22
WO2001044207A8 (fr) 2001-07-12
IL150037A0 (en) 2002-12-01
BR0017023A (pt) 2002-12-03
AU780711B2 (en) 2005-04-14
IL150037A (en) 2007-02-11
EP1242389B1 (fr) 2004-04-21
PL203819B1 (pl) 2009-11-30
CA2398772C (fr) 2011-07-05
WO2001044207A2 (fr) 2001-06-21
YU43902A (sh) 2005-03-15
AU2525901A (en) 2001-06-25
MEP12108A (en) 2010-06-10
SK285994B6 (sk) 2008-01-07
RS50289B (sr) 2009-09-08
KR20020061002A (ko) 2002-07-19
CZ302460B6 (cs) 2011-06-01
FR2802530A1 (fr) 2001-06-22
ATE264847T1 (de) 2004-05-15
JP4146641B2 (ja) 2008-09-10
EA004957B1 (ru) 2004-10-28
TR200401775T4 (tr) 2004-09-21
EE04778B1 (et) 2007-02-15
UA73333C2 (en) 2005-07-15
HUP0204080A2 (hu) 2003-04-28
IS6402A (is) 2002-05-28
EA200200523A1 (ru) 2002-12-26
SK8502002A3 (en) 2003-02-04
CO5251379A1 (es) 2003-02-28
DE60010126D1 (de) 2004-05-27
PL355811A1 (en) 2004-05-17
NO20022828L (no) 2002-08-19
TR200201600T2 (tr) 2002-10-21
WO2001044207A3 (fr) 2001-12-20
DE60010126T2 (de) 2005-04-28
PT1242389E (pt) 2004-08-31
EE200200331A (et) 2003-06-16
CN1293061C (zh) 2007-01-03
CN1434808A (zh) 2003-08-06
TWI289554B (en) 2007-11-11
MXPA02006033A (es) 2003-01-28
US6806282B2 (en) 2004-10-19
IS2315B (is) 2007-11-15
AR031837A1 (es) 2003-10-08
NO20022828D0 (no) 2002-06-13
ES2219436T3 (es) 2004-12-01
DK1242389T3 (da) 2004-08-09
US20030162771A1 (en) 2003-08-28
CZ20022099A3 (cs) 2002-09-11
EP1242389A2 (fr) 2002-09-25
KR100705525B1 (ko) 2007-04-10

Similar Documents

Publication Publication Date Title
HUP0204245A3 (en) Novel n-azabicyclo-amide derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0203316A3 (en) Amino-triazolopyridine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0100731A3 (en) New oxazolidine-, thiazolidine-, pyrrolidine-and piperidin derivatives process for their preparation and pharmaceutical compositions containing them
HUP0103913A3 (en) Novel form of irbesartan, methods for obtaining said form and pharmaceutical compositions containing same
HUP0001555A3 (en) Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
HU9800291D0 (en) Use of amido-pirimidine derivatives for producing pharmaceutical compositions for inhibiting decrease of glucose-metabolismus
HUP0201516A2 (en) 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0303118A3 (en) Novel 1,3-dihydro-2h-indol-one derivatives, method for preparing same and pharmaceutical compositions containing them
HUP0201753A3 (en) Pyridopyranoazepine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0203184A3 (en) Isoxazolecarboxamide derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0202731A3 (en) O-anisamide derivatives, process for their preparation and pharmaceutical compositions containing them
HK1055947A1 (en) Novel branched substituted amino derivatives of 3-amino-1-phenyl-1H-Ä1,2,4Ütriazol, methods for producing them and pharmaceutical compositions containing them
HUP0202988A3 (en) Substituted 3-phenyl-5-alkoxi-1,3,4-oxdiazol-2-one derivatives and their use as lipase inhibitors, process for their preparation and pharmaceutical compositions containing them
HUP0101234A3 (en) Betha-carboline derivatives, process for their preparation and pharmaceutical compositions thereof
HUP0004663A3 (en) Substituted isoquinoline derivatives, process for producing them and use of them for producing pharmaceutical compositions as anticonvulsants and pharmaceutical compositions containing them
HUP0102895A3 (en) Cyclopentanone dihydropyridine derivatives, use of them for producing pharmaceutical compositions and pharmaceutical compositions containing them
HUP0003766A2 (en) Isoguinolin derivatives, process for producing them and pharmaceutical compositions containing them
HUP0200993A3 (en) Thio-oxindole derivatives, use of them for producing pharmaceutical compositions and pharmaceutical compositions containing them
HUP0001183A3 (en) Pyrrolothiazine and pyrrolothiazepine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0001441A3 (en) Process for the preparation of pharmaceutical compositions containing 4-aza-androst-1-ene derivatives
HUP0004177A3 (en) 4,5-diaryloxazole derivatives, pharmaceutical compositions containing them and process for producing them
HUP0200643A3 (en) Dibenzoazulene derivatives, pharmaceutical compositions containing them, process for producing them and use of them for producing pharmaceutical compositions
HUP0203034A3 (en) Nitroxy derivatives of (r) and (s)-carnitine, process for their preparation and pharmaceutical compositions containing them
HUP0001432A3 (en) Pyrroloazepine derivatives, process for their preparation and pharmaceutical compositions containing them
SI1242389T1 (en) Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h(1,2,4)triazol, methods for producing them and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
CHPA Change of a particular in the register (except of change of ownership)
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20111214