HK1051186A1 - -α信號調節劑 - Google Patents

-α信號調節劑

Info

Publication number
HK1051186A1
HK1051186A1 HK03103293.5A HK03103293A HK1051186A1 HK 1051186 A1 HK1051186 A1 HK 1051186A1 HK 03103293 A HK03103293 A HK 03103293A HK 1051186 A1 HK1051186 A1 HK 1051186A1
Authority
HK
Hong Kong
Prior art keywords
tnf
modulators
alpha signalling
signalling
alpha
Prior art date
Application number
HK03103293.5A
Other languages
English (en)
Inventor
Scott F Sneddon
John L Kane
Bradford H Hirth
Fred Vinick
Shuang Qiao
Sharon R Nahill
M Williams John
Biemann Hans-Peter
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of HK1051186A1 publication Critical patent/HK1051186A1/zh

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
HK03103293.5A 2000-05-12 2003-05-12 -α信號調節劑 HK1051186A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20378400P 2000-05-12 2000-05-12
US20521300P 2000-05-18 2000-05-18
PCT/US2001/015027 WO2001087849A2 (en) 2000-05-12 2001-05-10 Modulators of tnf- alpha signaling

Publications (1)

Publication Number Publication Date
HK1051186A1 true HK1051186A1 (zh) 2003-07-25

Family

ID=26898898

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03103293.5A HK1051186A1 (zh) 2000-05-12 2003-05-12 -α信號調節劑

Country Status (13)

Country Link
US (5) US6969728B2 (zh)
EP (1) EP1294699B1 (zh)
JP (3) JP4960565B2 (zh)
KR (1) KR100840816B1 (zh)
CN (1) CN100494182C (zh)
AU (2) AU5969101A (zh)
BR (1) BR0111158A (zh)
CA (3) CA2408408C (zh)
HK (1) HK1051186A1 (zh)
IL (2) IL152450A0 (zh)
MX (1) MXPA02010993A (zh)
NO (1) NO324693B1 (zh)
WO (1) WO2001087849A2 (zh)

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US20060173010A1 (en) 2006-08-03
US20150126512A1 (en) 2015-05-07
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CA2781858C (en) 2015-03-31
WO2001087849A3 (en) 2002-06-06
AU5969101A (en) 2001-11-26
CA2876779A1 (en) 2001-11-22
KR100840816B1 (ko) 2008-06-23
NO324693B1 (no) 2007-12-03
JP2003533515A (ja) 2003-11-11
CN1441787A (zh) 2003-09-10
IL152450A (en) 2009-09-01
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CA2781858A1 (en) 2001-11-22
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US7034031B2 (en) 2006-04-25
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US20040171617A1 (en) 2004-09-02
US8518999B2 (en) 2013-08-27
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US20020119988A1 (en) 2002-08-29
US6969728B2 (en) 2005-11-29
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JP2014129406A (ja) 2014-07-10
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JP4960565B2 (ja) 2012-06-27

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